Open Access Articles ::: Current Drug Targets

ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)


Volume 18, 16 Issues, 2017


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Current Drug Targets

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Editor-in-Chief:
Francis J. Castellino
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA


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Current: 3.236
5 - Year: 3.344

Open Access Articles

TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*


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Aspirin Intolerance: Experimental Models for Bed-to-Bench

, 2016; 17(16): 1963 - 1970

Masamichi Yamashita


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Pharmacological Chaperones that Protect Tetrahydrobiopterin Dependent Aromatic Amino Acid Hydroxylases Through Different Mechanisms

, 2016; 17(13): 1515 - 1526

Magnus Hole, Ana Jorge-Finnigan, Jarl Underhaug, Knut Teigen and Aurora Martinez


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Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga


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Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy

, 2016; 17(8): 954 - 970

Mark Walsh, Stephanie Fritz, Daniel Hake, Michael Son, Sarah Greve, Manar Jbara, Swetha Chitta, Braxton Fritz, Adam Miller, Mary K Bader, Jonathon McCollester, Sophia Binz, Alyson Liew-Spilger, Scott Thomas, Anton Crepinsek, Faisal Shariff, Victoria Ploplis and Francis J. Castellino


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Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance

, 2016; 17(2): 164 - 177

Gabriela Nestal de Moraes, Laura Bella, Stefania Zona, Matthew J. Burton and Eric W.-F. Lam


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Biologics for Extraintestinal Manifestations of IBD

, 2014; 15(11): 1064 - 1073

Stephan R. Vavricka, Michael Scharl, Martin Gubler and Gerhard Rogler


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Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis

, 2013; 14(11): 1347 - 1356

Nian-Hua Ding, Jian Jian Li and Lun-Quan Sun


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Acute and Chronic Stress-Induced Disturbances of Microglial Plasticity, Phenotype and Function

, 2013; 14(11): 1262 - 1276

Frederick Rohan Walker, Michael Nilsson and Kimberley Jones


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Serum S100B Represents a New Biomarker for Mood Disorders

, 2013; 14(11): 1237 - 1248

Matthias L. Schroeter, Julia Sacher, Johann Steiner, Peter Schoenknecht and Karsten Mueller


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Perioperative Handling of Antiplatelet Drugs. A Critical Appraisal

, 2013; 14(8): 880 - 888

Matteo Nicola Dario Di Minno, Marco Milone, Pasquale Mastronardi, Pasquale Ambrosino, Alessandro Di Minno, Alessandro Parolari, Elena Tremoli and Domenico Prisco


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Oxidation Inhibits Iron-Induced Blood Coagulation

, 2013; 14(1): 13 - 19

Etheresia Pretorius, Janette Bester, Natasha Vermeulen and Boguslaw Lipinski


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Tissue-Based Approaches to Study Pharmacodynamic Endpoints in Early Phase Oncology Clinical Trials

, 2012; 13(12): 1525 - 1534

Joo Ern Ang, Stan Kaye and Udai Banerji


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Overcoming Drug Resistance and Treating Advanced Prostate Cancer

, 2012; 13(10): 1308 - 1323

Julius Semenas, Cinzia Allegrucci, Stephen A. Boorjian, Nigel P. Mongan and Jenny Liao Persson


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Molecular Pathology of Pancreatic Cancer: From Bench-to-Bedside Translation

, 2012; 13(6): 744 - 752

Vincenzo Corbo, Giampaolo Tortora and Aldo Scarpa


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Novel and Viable Acetylcholinesterase Target Site for Developing Effective and Environmentally Safe Insecticides

, 2012; 13(4): 471 - 482

Yuan-Ping Pang, Stephen Brimijoin, David W. Ragsdale, Kun Yan Zhu and Robert Suranyi


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Architecture and Conservation of the Bacterial DNA Replication Machinery, an Underexploited Drug Target

, 2012; 13(3): 352 - 372

Andrew Robinson, Rebecca J. Causer and Nicholas E. Dixon


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Vaccines and Other Immunological Approaches for Cancer Immunoprevention

, 2011; 12(13): 1957 - 1973

Pier-Luigi Lollini, Giordano Nicoletti, Lorena Landuzzi, Federica Cavallo, Guido Forni, Carla De Giovanni and Patrizia Nanni


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The Professional Phagocyte Dictyostelium discoideum as a Model Host for Bacterial Pathogens

, 2011; 12(7): 942 - 954

Salvatore Bozzaro and Ludwig Eichinger


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Host-Pathogen Interactions Made Transparent with the Zebrafish Model

, 2011; 12(7): 1000 - 1017

Annemarie H. Meijer and Herman P. Spaink


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Properties and Therapeutic Potential of Transient Receptor Potential Channels with Putative Roles in Adversity: Focus on TRPC5, TRPM2 and TRPA1

, 2011; 12(5): 724 - 736

L. H. Jiang, N. Gamper and D. J. Beech


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The Molecular Mechanisms of Glucocorticoids-Mediated Neutrophil Survival

, 2011; 12(4): 556 - 562

Arash S. Saffar, Heather Ashdown and Abdelilah S. Gounni


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Heme Oxygenase-1 in Tumor Biology and Therapy

, 2010; 11(12): 1551 - 1570

Halina Was, Jozef Dulak and Alicja Jozkowicz


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Involvement of the Toxic AGEs (TAGE)-RAGE System in the Pathogenesis of Diabetic Vascular Complications: A Novel Therapeutic Strategy

, 2010; 11(11): 1468 - 1482

Masayoshi Takeuchi, Jun-ichi Takino and Sho-ichi Yamagishi


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The Macrophage Stimulating Protein/Ron Pathway as a Potential Therapeutic Target to Impede Multiple Mechanisms Involved in Breast Cancer Progression

, 2010; 11(9): 1157 - 1168

Kelsi L. Kretschmann, Henok Eyob, Saundra S. Buys and Alana L. Welm


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MicroRNA-21: From Cancer to Cardiovascular Disease

, 2010; 11(8): 926 - 935

Virginija Jazbutyte and Thomas Thum


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Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1

, 2009; 10(12): 1212 - 1226

Akanksha Gupta, Mark D. Williams, William L. Macias, Bruce A. Molitoris and Brian W. Grinnell


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Inflammatory Systemic Biomarkers in Setting Acute Coronary Syndromes - Effects of the Diurnal Variation

, 2009; 10(10): 1001 - 1008

A. Dominguez-Rodriguez, P. Abreu-Gonzalez and J. C. Kaski


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Atherosclerosis and Arterial Blood Pressure in Mice

, 2007; 8(11): 1181 - 1189

Hong Lu, Lisa A. Cassis and Alan Daugherty


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GSK3 at the Edge: Regulation of Developmental Specification and Cell Polarization

, 2006; 7(11): 1411 - 1419

Leung Kim and Alan R. Kimmel


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