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Age-related Macular Degeneration: Current Knowledge of Zinc Metalloproteinases Involvement


Francesca Liva, Doretta Cuffaro, Elisa Nuti, Susanna Nencetti, Elisabetta Orlandini, Giovanni Vozzi and Armando Rossello*


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The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets


Benjamin J Buckley*, Umar Ali, Michael J Kelso and Marie Ranson


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A Review of Preclinical Experiments Toward Targeting M2 Macrophages in Prostate Cancer


Farhad Seif, Laleh Sharifi, Majid Khoshmirsafa, Yasaman Mojibi and Monireh Mohsenzadegan *


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Nanonetworks in Biomedical Applications


Marzo J. L.*, Jornet J. M and Pierobon M.


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Photopolymerizable Resins for 3D-Printing Tissue Engineered Implants


Antonio J. Guerra, Hernan Lara-Padilla, Luiz H. Catalani, Matthew L. Becker, Ciro A. Rodriguez and David Dean*


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The Need to Consider Context in the Evaluation of Anti-infectious and Immunomodulatory Effects of Vitamin A and its Derivatives


Pedro Xavier-Elsas*, Bruno Marques Vieira, Daniela Masid-de-Brito, Monica Gomes Barradas and Maria Ignez C. Gaspar-Elsas


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Drug Development Strategy for Type 2 Diabetes: Targeting Positive Energy Balances


Zhenqi Liu and Baichun Yang*


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Cellular Senescence and Anti-Cancer Therapy


Jieqiong You, Rong Dong, Meidan Ying, Qiaojun He, Ji Cao and Bo Yang*


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The Impact of Statin Therapy on the Survival of Patients with Gastrointestinal Cancer


Meysam Gachpazan, Hoda Kashani, Majid Khazaei, Seyed Mahdi Hassanian, Majid Rezayi, Fereshteh Asgharzadeh Yazdi, Majid Ghayour-Mobarhan, Gordon A. Ferns and Amir Avan*


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Potential Applications of Induced Pluripotent Stem Cells for Cardiovascular Diseases


Xiaotong Wang, Ye Yuan, Zhenbo Han, Ying Yu, Zihang Xu and Benzhi Cai*


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The Plasminogen Activation System Promotes Neurorepair in the Ischemic Brain


Manuel Yepes*


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Heat Shock Proteins (HSPs): A Novel Target for Cancer Metastasis Prevention


Vinayak Narayanankutty , Arunaksharan Narayanankutty* and Anusree Nair


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Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review


Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *


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Opportunities of Bacterial Cellulose to Treat Epithelial Tissues


Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch


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Potential Therapeutic Agents Against Par-4 Target for Cancer Treatment: Where Are We Going?


Renata Virgínia Cavalcanti Santos, Wanessa Layssa Batista de Sena, Flaviana Alves dos Santos, Antônio Felix da Silva Filho, Marina Galdino da Rocha Pitta, Maira Galdino da Rocha Pitta, Moacyr Barreto de Melo Rego and Michelly Cristiny Pereira*


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Investigational Hypoxia-Activated Prodrugs: Making Sense of Future Development


Min-Xia Su, Le-Le Zhang, Zhang-Jian Huang, Jia-Jie Shi and Jin-Jian Lu*


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Three-Dimensional Manufactured Supports for Breast Cancer Stem Cell Population Characterization


Emma Polonio-Alcalá, Marc Rabionet, Santiago Ruiz-Martínez, Joaquim Ciurana* and Teresa Puig*


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Aryl Hydrocarbon Receptor: Its Regulation and Roles in Transformation and Tumorigenesis


Xun Che and Wei Dai*


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Developing Practical Therapeutic Strategies that Target Protein SUMOylation


Olivia F. Cox and Paul W. Huber*


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Estrogen Receptor Alpha and its Ubiquitination in Breast Cancer Cells


Angeles C. Tecalco-Cruz*, Josue O. Ramirez-Jarquin and Eduardo Cruz-Ramos


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Preparation and Applications of Glyconanoparticles


Gangliang Huang*


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