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"In view of the growing volume of literature, the role of high quality review journals has become increasingly important. Current Drug Targets is an important journal in the field of medicinal chemistry and drug design, which is strongly recommended to the scientific community."

Jean-Marie Lehn
Nobel Laureate

Forthcoming Special Issues

Nanotechnology in biomedical applications


Guest Editor(s): Teresa Puig, Joaquim Ciurana
Tentative Publication Date: April, 2019
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Published Special Issues

Apixaban from Bench to Bedside


Current Drug Targets, Volume 19, Number 06
Guest Editor(s): Marco Matteo Ciccone

Authors' Comments
It was a nice experience to publish our article in current drug target. I felt that the journal is quick and has maintained very high standard by independently reviewing article from more than five reviewers. The communication between the author and the Journals editorial is also speedy. I hope the journal will continue to maintain and sustain its reputation

Pushpender K. Sharma
(Department of Biotechnology, Sri Guru Granth Sahib World University, Fatehgarh Sahib, Pb, India)


Current Drug Targets

,

Volume 19

-

Number 16



Review Article

A New Investigational Perspective for Purines Against Glioblastoma Invasiveness

, 19(16): 1871 - 1881

Patricia Giuliani, Mariachiara Zuccarini, Marzia Carluccio, Sihana Ziberi, Patrizia Di Iorio, Francesco Caciagli and Renata Ciccarelli*


DOI: 10.2174/1389450119666180226123819




Review Article   Open Access



Review Article



Review Article



Review Article



Review Article



Review Article

New Light on An Old Friend: Targeting PUMA in Radioprotection and Therapy of Cardiovascular and Neurodegenerative Diseases

, 19(16): 1943 - 1957

Ales Tichy, Jan Marek, Radim Havelek*, Jaroslav Pejchal, Martina Seifrtova, Lenka Zarybnicka, Alzbeta Filipova, Martina Rezacova and Zuzana Sinkorova


DOI: 10.2174/1389450119666180406110743




Review Article



Current Drug Targets, Volume 20 (2019) - Number 1


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print






Snake Venom Disintegrins: An Overview of their Interaction with Integrins


Pedro Henrique Souza Cesar, Mariana Aparecida Braga, Marcus Vinicius Cardoso Trento, Danilo Luccas Menaldo and Silvana Marcussi*


View Abstract View on PubMed


CDK9 as an Appealing Target for Therapeutic Interventions


Shirin Eyvazi, Mohammad Saeid Hejazi, Homan Kahroba, Mozghan Abasi, Reza Eghdam Zamiri and Vahideh Tarhriz*


View Abstract View on PubMed



Estrogen Receptor Alpha and its Ubiquitination in Breast Cancer Cells


Angeles C. Tecalco-Cruz*, Josue O. Ramirez-Jarquin and Eduardo Cruz-Ramos


View Abstract View on PubMed



Editor's Choice


Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer

, 2018; 19(15): 1731 - 1737

Marcin Włodarczyk*, Jakub Włodarczyk, Paweł Siwiński, Aleksandra Sobolewska-Włodarczyk and Jakub Fichna


DOI: 10.2174/1389450119666180803122744



Epigenetic Mechanisms: Role in Hematopoietic Stem Cell Lineage Commitment and Differentiation

, 2018; 19(14): 1683 - 1695

Sanjeev Raghuwanshi, Swati Dahariya, Ravinder Kandi, Usha Gutti, Ram Babu Undi, Durga Shankar Sharma, Itishri Sahu, Narasaiah Kovuru, Nagendra Sastry Yarla, Raja Gopal Venakata Saladi and Ravi Kumar Gutti*


DOI: 10.2174/1389450118666171122141821




The Role of Dietary Compounds in the Therapy of Nicotine-Induced Osteoporosis

, 2018; 19(12): 1424 - 1430

Norazlina Mohamed*, Norliza Muhammad, Ahmad Nazrun Shuid and Ima-Nirwana Soelaiman


DOI: 10.2174/1389450118666170925154428



Role of the LDL Receptor-Related Protein 1 in Regulating Protease Activity and Signaling Pathways in the Vasculature

, 2018; 19(11): 1276 - 1288

Dianaly T. Au, Allison L. Arai, William E. Fondrie, Selen C. Muratoglu* and Dudley K. Strickland*


DOI: 10.2174/1389450119666180511162048



The Role of DNA Repair Pathways in AML Chemosensitivity

, 2018; 19(10): 1205 - 1219

Elizabeth A. Pearsall, Lisa F. Lincz and Kathryn A. Skelding*


DOI: 10.2174/1389450119666180110093713






Open Access Articles

Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano








TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Tapping into Mitochondria to Find Novel Targets for Diabetes Complications

, 2016; 17(12): 1341 - 1349

Nicole B. Flemming, Linda A. Gallo, Micheal S. Ward and Josephine M. Forbes




Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga




Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy

, 2016; 17(8): 954 - 970

Mark Walsh, Stephanie Fritz, Daniel Hake, Michael Son, Sarah Greve, Manar Jbara, Swetha Chitta, Braxton Fritz, Adam Miller, Mary K Bader, Jonathon McCollester, Sophia Binz, Alyson Liew-Spilger, Scott Thomas, Anton Crepinsek, Faisal Shariff, Victoria Ploplis and Francis J. Castellino




Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance

, 2016; 17(2): 164 - 177

Gabriela Nestal de Moraes, Laura Bella, Stefania Zona, Matthew J. Burton and Eric W.-F. Lam




Biologics for Extraintestinal Manifestations of IBD

, 2014; 15(11): 1064 - 1073

Stephan R. Vavricka, Michael Scharl, Martin Gubler and Gerhard Rogler






Most Cited Articles

AMPK as a New Attractive Therapeutic Target for Disease Prevention: The Role of Dietary Compounds AMPK and Disease Prevention

, 2016; 17(8): 865-889.

Massimiliano Gasparrini, Francesca Giampieri, Josè M. Alvarez Suarez, Luca Mazzoni, Tamara Y. Forbes Hernandez, Josè L. Quiles, Pedro Bullon and Maurizio Battino


DOI: 10.2174/1573399811666150615150235


B1-Metallo- β-Lactamases: Where Do We Stand?

, 2016; 17(9): 1029-1050.

Maria F. Mojica, Robert A. Bonomo and Walter Fast


DOI: 10.2174/1389450116666151001105622




Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

, 2017; 18(6): 705-718.

Andreia Neves Carvalho*, Omidreza Firuzi, Maria Joao Gama, Jack van Horssen and Luciano Saso


DOI: 10.2174/1389450117666160401120514


Virological and Clinical Response to Interferon-Free Regimens in Patients with HCV-Related Mixed Cryoglobulinemia: Preliminary Results of a Prospective Pilot Study

, 2017; 18(7): 772-785.

Laura Gragnani, Alessia Piluso, Teresa Urraro, Alessio Fabbrizzi, Elisa Fognani, Luisa Petraccia, Alessandro Genovesi, Lidia Giubilei, Jessica Ranieri, Cristina Stasi, Monica Monti and Anna Linda Zignego*


DOI: 10.2174/1389450117666160208145432




Sirtuins: Possible Clinical Implications in Cardio and Cerebrovascular Diseases

, 2017; 18(4): 473-484.

Valeria Conti, Maurizio Forte, Graziamaria Corbi, Giusy Russomanno, Luigi Formisano, Alessandro Landolfi, Viviana Izzo, Amelia Filippelli, Carmine Vecchione and Albino Carrizzo


DOI: 10.2174/1389450116666151019095903


Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib

, 2016; 17(7): 783-799.

Gianluigi Mazzoccoli, Luca Miele, Jude Oben, Antonio Grieco and Manlio Vinciguerra


DOI: 10.2174/1389450117666151209120831



Most Accessed Articles



Pathological Roles of Iron in Cardiovascular Disease

, 2018; 19(9): 1068-1076.

Motoi Kobayashi, Tomohiro Suhara, Yuichi Baba, Nicholas K. Kawasaki, Jason K. Higa and Takashi Matsui*


DOI: 10.2174/1389450119666180605112235






Novel Pharmacotherapeutic Approaches in Treatment of Alcohol Addiction

, 2018; 19(12): 1378-1390.

Rashidi Mohamed Pakri Mohamed, Jaya Kumar*, Shihad Udin Ahmad and Isa Naina Mohamed


DOI: 10.2174/1389450119666180523092534





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