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Current Drug Targets

Volume 20, 16 Issues, 2019
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

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Volume 20

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Number 5



Editorial   Open Access



Review Article



Review Article



Review Article



Review Article



Review Article



Review Article

Understanding Membrane Protein Drug Targets in Computational Perspective

, 20(5): 551 - 564

Jianting Gong, Yongbing Chen, Feng Pu, Pingping Sun, Fei He, Li Zhang, Yanwen Li*, Zhiqiang Ma* and Han Wang*


DOI: 10.2174/1389450120666181204164721


Review Article



Current Drug Targets, Volume 20 (2019) - Number 6


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Opportunities of Bacterial Cellulose to Treat Epithelial Tissues


Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch


View Abstract View on PubMed


Potential Applications of Induced Pluripotent Stem Cells for Cardiovascular Diseases


Xiaotong Wang, Zhenbo Han, Ying Yu, Zihang Xu, Benzhi Cai and Ye Yuan*


View Abstract View on PubMed


Significance and Mechanisms of P-glycoprotein in Central Nervous System Diseases


Liangliang Huang, Binbin Li, Xiang Li, Ge Liu, Rui Liu, Jia Guo, Baohui Xu, Yunman Li* and Weirong Fang*


View Abstract



MicroRNAs as Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma


Seyed Mostafa Parizadeh*, Reza Jafarzadeh-Esfehani*, Maryam Ghandehari, Fatemeh Goldani, Seyed Mohammad Reza Parizadeh, Seyed Mahdi Hassanian, Majid Ghayour-Mobarhan, Gordon A. Ferns and Amir Avan


View Abstract View on PubMed


NOB1: A Potential Biomarker or Target in Cancer


Weiwei Ke, Zaiming Lu and Xiangxuan Zhao*


View Abstract


Loss of the Tumor Suppressor HACE1 Contributes to Cancer Progression


Jun-Chen Li, Xing Chang, Yang Chen, Xin-Zhe Li, Xiang-Lian Zhang, Shi-Ming Yang, Chang-Jiang Hu* and Hao Zhang*


View Abstract View on PubMed




Abstracts Ahead of Print


Prevention of postoperative recurrence in CD: tailoring treatment to patient profile


Marjorie Argollo, Paulo Gustavo Kotze, Laura Lamonaca, Daniela Gilardi, Federica Furfaro, Takayuki Yamamoto and Silvio Danese*


View Abstract


Molecular Aspects of Melatonin Treatment in Tinnitus; a Review


Azam Hosseinzadeh, Seyed Kamran Kamrava, Brian C. J. Moore, Russel J. Reiter, Habib Ghaznavi, Mahboobeh Kamali and Saeed Mehrzadi*


View Abstract


Nano Drug Delivery in Treatment of Oral Cancer, A Review of the Literature


Vandita Kakkar*, Manoj Kumar Verma, Komal Saini and Indu Pal Kaur


View Abstract


The use of naltrexone in dermatology. Current evidence and future directions.


Mariusz Sikora*, Adriana Rakowska, Małgorzata Olszewska and Lidia Rudnicka


View Abstract


Editor's Choice

Understanding Membrane Protein Drug Targets in Computational Perspective

, 2019; 20(5): 551 - 564

Jianting Gong, Yongbing Chen, Feng Pu, Pingping Sun, Fei He, Li Zhang, Yanwen Li*, Zhiqiang Ma* and Han Wang*


DOI: 10.2174/1389450120666181204164721



Influence of Ultrafine Particles Exposure on Asthma Exacerbation in Children: A Meta-Analysis

, 2019; 20(4): 412 - 420

Qinyuan Li, Qian Yi, Lin Tang, Siying Luo, Yuan Tang, Guangli Zhang and Zhengxiu Luo*


DOI: 10.2174/1389450119666180829114252



A Review on Quantum Dots: Synthesis to In- silico Analysis as Next Generation Antibacterial Agents

, 2019; 20(3): 255 - 262

Sounik Manna, Munmun Ghosh, Ranadhir Chakraborty, Sudipto Ghosh and Santi M. Mandal*


DOI: 10.2174/1389450119666180731142423






Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer

, 2018; 19(15): 1731 - 1737

Marcin Włodarczyk*, Jakub Włodarczyk, Paweł Siwiński, Aleksandra Sobolewska-Włodarczyk and Jakub Fichna


DOI: 10.2174/1389450119666180803122744



Epigenetic Mechanisms: Role in Hematopoietic Stem Cell Lineage Commitment and Differentiation

, 2018; 19(14): 1683 - 1695

Sanjeev Raghuwanshi, Swati Dahariya, Ravinder Kandi, Usha Gutti, Ram Babu Undi, Durga Shankar Sharma, Itishri Sahu, Narasaiah Kovuru, Nagendra Sastry Yarla, Raja Gopal Venakata Saladi and Ravi Kumar Gutti*


DOI: 10.2174/1389450118666171122141821




The Role of Dietary Compounds in the Therapy of Nicotine-Induced Osteoporosis

, 2018; 19(12): 1424 - 1430

Norazlina Mohamed*, Norliza Muhammad, Ahmad Nazrun Shuid and Ima-Nirwana Soelaiman


DOI: 10.2174/1389450118666170925154428



Open Access Articles



Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga




Targeted Thromboelastographic (TEG) Blood Component and Pharmacologic Hemostatic Therapy in Traumatic and Acquired Coagulopathy

, 2016; 17(8): 954 - 970

Mark Walsh, Stephanie Fritz, Daniel Hake, Michael Son, Sarah Greve, Manar Jbara, Swetha Chitta, Braxton Fritz, Adam Miller, Mary K Bader, Jonathon McCollester, Sophia Binz, Alyson Liew-Spilger, Scott Thomas, Anton Crepinsek, Faisal Shariff, Victoria Ploplis and Francis J. Castellino




Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance

, 2016; 17(2): 164 - 177

Gabriela Nestal de Moraes, Laura Bella, Stefania Zona, Matthew J. Burton and Eric W.-F. Lam




Biologics for Extraintestinal Manifestations of IBD

, 2014; 15(11): 1064 - 1073

Stephan R. Vavricka, Michael Scharl, Martin Gubler and Gerhard Rogler






Serum S100B Represents a New Biomarker for Mood Disorders

, 2013; 14(11): 1237 - 1248

Matthias L. Schroeter, Julia Sacher, Johann Steiner, Peter Schoenknecht and Karsten Mueller





Most Cited Articles

AMPK as a New Attractive Therapeutic Target for Disease Prevention: The Role of Dietary Compounds AMPK and Disease Prevention

, 2016; 17(8): 865-889.

Massimiliano Gasparrini, Francesca Giampieri, Josè M. Alvarez Suarez, Luca Mazzoni, Tamara Y. Forbes Hernandez, Josè L. Quiles, Pedro Bullon and Maurizio Battino


DOI: 10.2174/1573399811666150615150235


B1-Metallo- β-Lactamases: Where Do We Stand?

, 2016; 17(9): 1029-1050.

Maria F. Mojica, Robert A. Bonomo and Walter Fast


DOI: 10.2174/1389450116666151001105622




Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

, 2017; 18(6): 705-718.

Andreia Neves Carvalho*, Omidreza Firuzi, Maria Joao Gama, Jack van Horssen and Luciano Saso


DOI: 10.2174/1389450117666160401120514


Virological and Clinical Response to Interferon-Free Regimens in Patients with HCV-Related Mixed Cryoglobulinemia: Preliminary Results of a Prospective Pilot Study

, 2017; 18(7): 772-785.

Laura Gragnani, Alessia Piluso, Teresa Urraro, Alessio Fabbrizzi, Elisa Fognani, Luisa Petraccia, Alessandro Genovesi, Lidia Giubilei, Jessica Ranieri, Cristina Stasi, Monica Monti and Anna Linda Zignego*


DOI: 10.2174/1389450117666160208145432




Sirtuins: Possible Clinical Implications in Cardio and Cerebrovascular Diseases

, 2017; 18(4): 473-484.

Valeria Conti, Maurizio Forte, Graziamaria Corbi, Giusy Russomanno, Luigi Formisano, Alessandro Landolfi, Viviana Izzo, Amelia Filippelli, Carmine Vecchione and Albino Carrizzo


DOI: 10.2174/1389450116666151019095903


Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib

, 2016; 17(7): 783-799.

Gianluigi Mazzoccoli, Luca Miele, Jude Oben, Antonio Grieco and Manlio Vinciguerra


DOI: 10.2174/1389450117666151209120831



Most Accessed Articles




CD93: Recent Advances and Implications in Disease

, 2012; 13(3): 411-420.

Mallary C. Greenlee-Wacker, Manuel D. Galvan and Suzanne S. Bohlson


DOI: 10.2174/138945012799424651



Melatonin as Potential Targets for Delaying Ovarian Aging

, 2019; 20(1): 16-28.

Yanzhou Yang*, Hoi-Hung Cheung, Cheng Zhang, Ji Wu and Wai-Yee Chan


DOI: 10.2174/1389450119666180828144843




Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer

, 2018; 19(15): 1731-1737.

Marcin Włodarczyk*, Jakub Włodarczyk, Paweł Siwiński, Aleksandra Sobolewska-Włodarczyk and Jakub Fichna


DOI: 10.2174/1389450119666180803122744




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