Contents

Current Drug Metabolism, Volume 9 - Number 5

Editorial

, 9(5): 361 - 362

Chandra Prakash


DOI: 10.2174/138920008784746418




Molecular Characterization of CYP2B6 Substrates

, 9(5): 363 - 373

Sean Ekins, Manisha Iyer, Matthew D. Krasowski and Evan D. Kharasch


DOI: 10.2174/138920008784746346




The Challenges of Dealing with Promiscuous Drug-Metabolizing Enzymes, Receptors and Transporters

, 9(5): 374 - 383

Qiang Ma and Anthony Y.H. Lu


DOI: 10.2174/138920008784746337




Cytochrome P450 Turnover: Regulation of Synthesis and Degradation, Methods for Determining Rates, and Implications for the Prediction of Drug Interactions

, 9(5): 384 - 393

Jiansong Yang, Mingxiang Liao, Magang Shou, Masoud Jamei, Karen Rowland Yeo, Geoffrey T. Tucker and Amin Rostami-Hodjegan


DOI: 10.2174/138920008784746382




An Update on Clinical Drug Interactions with the Herbal Antidepressant St. Johns wort

, 9(5): 394 - 409

Shu-Feng Zhou and Xinsheng Lai


DOI: 10.2174/138920008784746391




Metabolism of Atypical Antipsychotics: Involvement of Cytochrome P450 Enzymes and Relevance for Drug-Drug Interactions

, 9(5): 410 - 418

Liana Urichuk, Trevor I. Prior, Serdar Dursun and Glen Baker


DOI: 10.2174/138920008784746373




Applications and Limitations of Genetically Modified Mouse Models in Drug Discovery and Development

, 9(5): 419 - 438

Jiunn H. Lin


DOI: 10.2174/138920008784746355




Liver-Enriched Transcription Factors and Their Role in Regulating UDP Glucuronosyltransferase Gene Expression

, 9(5): 439 - 452

D. A. Gardner-Stephen and P. I. Mackenzie


DOI: 10.2174/138920008784746409




Heterotropic Cooperativity in Oxidation Mediated by Cytochrome P450

, 9(5): 453 - 462

Toshiro Niwa, Norie Murayama and Hiroshi Yamazaki


DOI: 10.2174/138920008784746364




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