Contents

Current Drug Metabolism, Volume 8 - Number 4

Expression and Function of Cytochrome P450 in Brain Drug Metabolism

, 8(4): 297 - 306

R. P. Meyer, M. Gehlhaus, R. Knoth and B. Volk


DOI: 10.2174/138920007780655478




CYP-Mediated Clozapine Interactions: How Predictable Are They?

, 8(4): 307 - 313

Manoranjenni Chetty and Michael Murray


DOI: 10.2174/138920007780655469




The Non-ABC Drug Transporter RLIP76 (RALBP-1) Plays a Major Role in the Mechanisms of Drug Resistance

, 8(4): 315 - 323

Yogesh C. Awasthi, Rajendra Sharma, Sushma Yadav, Seema Dwivedi, Abha Sharma and Sanjay Awasthi


DOI: 10.2174/138920007780655414




Role of P-Glycoprotein in the Intestinal Absorption of Tanshinone IIA, a Major Active Ingredient in the Root of Salvia miltiorrhiza Bunge

, 8(4): 325 - 340

Xi-Yong Yu, Shu-Guang Lin, Zhi-Wei Zhou, Xiao Chen, Jun Liang, Pei-Qing Liu, Wei Duan, Balram Chowbay, Jing-Yuan Wen, Chun-Guang Li and Shu-Feng Zhou


DOI: 10.2174/138920007780655450




Evaluation of Drug-Transporter Interactions Using In Vitro and In Vivo Models

, 8(4): 341 - 363

Cindy Q. Xia, Mark N. Milton and Liang-Shang Gan


DOI: 10.2174/138920007780655423




Transport of Cryptotanshinone, a Major Active Triterpenoid in Salvia Miltiorrhiza Bunge Widely Used in the Treatment of Stroke and Alzheimers Disease, Across the Blood-Brain Barrier

, 8(4): 365 - 377

Xi-Yong Yu, Shu-Guang Lin, Xiao Chen, Zhi-Wei Zhou, Jun Liang, Wei Duan, Balram Chowbay, Jing-Yuan Wen, Eli Chan, Jie Cao, Chun-Guang Li and Shu-Feng Zhou


DOI: 10.2174/138920007780655441




A Pharmacokinetic Interaction Between Clarithromycin and Sirolimus in Kidney Transplant Recipient

, 8(4): 379 - 381

Domenico Capone, Giuseppe Palmiero, Antonio Gentile, Vincenzo Basile, Stefano Federico, Massimo Sabbatini, Maria Potenza, Anna Perfetti, Maria Pieri and Giovanni Tarantino


DOI: 10.2174/138920007780655405




Histone Deacetylase Inhibitors: Molecular and Biological Activity as a Premise to Clinical Application

, 8(4): 383 - 394

V. Santini, A. Gozzini and G. Ferrari


DOI: 10.2174/138920007780655397




Synergistic Cytotoxic Activity of Recombinant TRAIL Plus the Non-Genotoxic Activator of the p53 Pathway Nutlin-3 in Acute Myeloid Leukemia Cells

, 8(4): 395 - 403

Paola Secchiero, Carlotta Zerbinati, Maria Grazia di Iasio, Elisabetta Melloni, Mario Tiribelli, Vittorio Grill and Giorgio Zauli


DOI: 10.2174/138920007780655432




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