Contents

Current Drug Metabolism, Volume 8 - Number 2

Ocular Disposition, Pharmacokinetics, Efficacy and Safety of Nanoparticle-Formulated Ophthalmic Drugs

, 8(2): 91 - 107

Hai-Zhi Bu, Hovhannes J. Gukasyan, Lance Goulet, Xiao-Jing Lou, Cathie Xiang and Tatiana Koudriakova


DOI: 10.2174/138920007779815977




Pharmacokinetic and Pharmacodynamic Variability: A Daunting Challenge in Drug Therapy

, 8(2): 109 - 136

Jiunn H. Lin


DOI: 10.2174/138920007779816002




Identification of a Novel Intestinal First Pass Metabolic Pathway: NQO1 Mediated Quinone Reduction and Subsequent Glucuronidation

, 8(2): 137 - 149

Haiping Hao, Guangji Wang, Nan Cui, Jing Li, Lin Xie and Zuoqi Ding


DOI: 10.2174/138920007779816011




Diffusion of Macromolecule Through Retina After Experimental Branch Retinal Vein Occlusion and Estimate of Intraretinal Barrier

, 8(2): 151 - 156

Yong Tao, Xiao-xin Li, Yan-rong Jiang, Xia-bing Bai, Bi-dong Wu and Jian-qiang Dong


DOI: 10.2174/138920007779815968




A Mechanistic Study on Altered Pharmacokinetics of Irinotecan by St. Johns Wort

, 8(2): 157 - 171

Ze-Ping Hu, Xiao-Xia Yang, Xiao Chen, Jie Cao, Eli Chan, Wei Duan, Min Huang, Xue-Qing Yu, Jing-Yuan Wen and Shu-Feng Zhou


DOI: 10.2174/138920007779815995




Metabolism of Sanguinarine: The Facts and The Myths

, 8(2): 173 - 176

Z. Dvorak and V. Simanek


DOI: 10.2174/138920007779815959




Modulation of Neurotransmitter Release by Carbon Monoxide at the Frog Neuro-Muscular Junction

, 8(2): 177 - 184

Guzel F. Sitdikova, Rustem R. Islamov, Marat A. Mukhamedyarov, Vladlena V. Permyakova, Andrey L. Zefirov and Andras Palotas


DOI: 10.2174/138920007779815940




Transcriptional Regulation and Expression of CYP3A4 in Hepatocytes

, 8(2): 185 - 194

Celia P. Martinez-Jimenez, Ramiro Jover, M. Teresa Donato, Jose V. Castell and M. Jose Gomez-Lechon


DOI: 10.2174/138920007779815986




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