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Contents

Current Drug Metabolism, Volume 8 - Number 1






Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver

, 8(1): 33 - 45

Zoe E. Barter, Martin K. Bayliss, Philip H. Beaune, Alan R. Boobis, David J. Carlile, Robert J. Edwards, J. Brian Houston, Brian G. Lake, John C. Lipscomb, Olavi R. Pelkonen, Geoffrey T. Tucke and Amin Rostami-Hodjegan


DOI: 10.2174/138920007779315053



Molecular Modeling-Guided Site-Directed Mutagenesis of Cytochrome P450 2D6

, 8(1): 59 - 77

Chris de Graaf, Chris Oostenbrink, Peter H. J. Keizers, Barbara M. A. van Vugt-Lussenburg, Robert A. B. van Waterschoot, Richard A. Tschirret-Guth, Jan N. M. Commandeur and Nico P. E. Vermeulen


DOI: 10.2174/138920007779315062




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