Contents

Current Drug Metabolism, Volume 7 - Number 4

Cytochrome P450 Expression in the Liver of Food-Producing Animals

, 7(4): 335 - 348

Costas Ioannides


DOI: 10.2174/138920006776873544




Evolution and Function of the NR1I Nuclear Hormone Receptor Subfamily (VDR, PXR, and CAR) with Respect to Metabolism of Xenobiotics and Endogenous Compounds

, 7(4): 349 - 365

E. J. Reschly and Matthew D. Krasowski


DOI: 10.2174/138920006776873526




Investigation of Exenatide Elimination and Its In Vivo and In Vitro Degradation

, 7(4): 367 - 374

Kathrin Copley, Kevin McCowen, Richard Hiles, Loretta L. Nielsen, Andrew Young and David G. Parkes


DOI: 10.2174/138920006776873490




Evaluation of 170 Xenobiotics as Transactivators of Human Pregnane X Receptor (hPXR) and Correlation to Known CYP3A4 Drug Interactions

, 7(4): 375 - 388

Michael Sinz, Sean Kim, Zhengrong Zhu, Taosheng Chen, Monique Anthony, Kenneth Dickinson and A. D. Rodrigues


DOI: 10.2174/138920006776873535




In Vitro Monitoring Picogram Roxithromycin in Human Urine Using Flow Injection Chemiluminescence Procedure

, 7(4): 389 - 395

Zhenghua Song, Yanhong Liu and Xiaofeng Xie


DOI: 10.2174/138920006776873481




Induction of the Hepatic Cytochrome P450 2B Subfamily by Xenobiotics: Research History, Evolutionary Aspect, Relation to Tumorigenesis, and Mechanism

, 7(4): 397 - 409

Hideyuki Yamada, Yuji Ishii, Midori Yamamoto and Kazuta Oguri


DOI: 10.2174/138920006776873508




Functional Expression of Human Cytochrome P450 Enzymes in Escherichia coli

, 7(4): 411 - 429

Chul-Ho Yun, Sung-Kun Yim, Dong-Hyun Kim and Taeho Ahn


DOI: 10.2174/138920006776873472




Pharmacokinetic Mechanisms for Reduced Toxicity of Irinotecan by Coadministered Thalidomide

, 7(4): 431 - 454

Xiao-Xia Yang, Ze-Ping Hu, Sui Y. Chan, Wei Duan, Paul C.-L. Ho, Urs A. Boelsterli, Ka-Yun Ng, Eli Chan, Jin-Song Bian, Yu-Zong Chen, Min Huang and > Zhou


DOI: 10.2174/138920006776873517




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