Contents

Current Drug Metabolism, Volume 6 - Number 5

Effect of Omeprazole on the Hydroxylation of Warfarin Enantiomers in Human: In-Vitro Studies with Liver Microsomes and cDNA-Expressed Cytochrome P450 Isozymes

, 6(5): 399 - 411

Q. Zhou, S. Zhou and E. Chan


DOI: 10.2174/138920005774330620




Cytochrome P450 Enzymes Mechanism Based Inhibitors: Common Sub-Structures and Reactivity

, 6(5): 413 - 451

E. Fontana, P. M. Dansette and S. M. Poli


DOI: 10.2174/138920005774330639




Coupling of Conjugating Enzymes and Efflux Transporters: Impact on Bioavailability and Drug Interactions

, 6(5): 455 - 468

E. J. Jeong, X. Liu, X. Jia, J. Chen and M. Hu


DOI: 10.2174/138920005774330657




CYP1A1 Is a Major Enzyme Responsible for the Metabolism of Granisetron in Human Liver Microsomes

, 6(5): 469 - 480

H. Nakamura, N. Ariyoshi, K. Okada, H. Nakasa, K. Nakazawa and M. Kitada


DOI: 10.2174/138920005774330666




Effect of Some Biologically Interesting Substituted Tetrahydro-1,4- Oxazines on Drug Metabolising Enzymes and on Inflammation

, 6(5): 481 - 485

E. A. Rekka, A. P. Kourounakis, N. Avramidis and P. N. Kourounakis


DOI: 10.2174/138920005774330648




Metabolism and Disposition of the Antiviral Nucleoside Analogue AM365 in the Isolated Perfused Rat Liver

, 6(5): 487 - 493

J. Wang, R. L. Nation, A. M. Evans, S. Cox and D. Shackleford


DOI: 10.2174/138920005774330611




Mechanisms of Male Infertility: Role of Antioxidants

, 6(5): 495 - 501

S. A. Sheweita, A. M. Tilmisany and H. Al-Sawaf


DOI: 10.2174/138920005774330594




Utility of Recombinant Cytochrome P450 Enzymes: A Drug Metabolism Perspective

, 6(5): 503 - 517

W. Tang, R. W. Wang and Anthony Y.H. Lu


DOI: 10.2174/138920005774330602




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