Contents

Current Drug Metabolism, Volume 5 - Number 5

Cigarette Smoking, Metabolic Activation and Carcinogenesis

, 5(5): 363 - 373

Akiyoshi Nishikawa, Yukio Mori, In-Seon Lee, Takuji Tanaka and Masao Hirose


DOI: 10.2174/1389200043335441




Biopharmaceutic Classification System: A Scientific Framework for Pharmacokinetic Optimization in Drug Research

, 5(5): 375 - 388

Manthena V.S. Varma, Sateesh Khandavilli, Yasvanth Ashokraj, Amit Jain, Anandbabu Dhanikula, Anurag Sood, Narisetty S. Thomas, Omathanu Pillai, Pradeep Sharma, Rajesh Gandhi, Shrutidevi Agrawal, Vinod Nair and Ramesh Panchagnula


DOI: 10.2174/1389200043335423




Metabonomics: Its Potential as a Tool in Toxicology for Safety Assessment and Data Integration

, 5(5): 389 - 398

J. L. Griffin and M. E. Bollard


DOI: 10.2174/1389200043335432




Effect of Growth Factors as Therapeutic Drugs on Hepatic Metabolism During the Systemic Inflammatory Response Syndrome

, 5(5): 399 - 413

Marc G. Jeschke and David N. Herndon


DOI: 10.2174/1389200043335405




Therapeutic Drugs that Behave as Mechanism-Based Inhibitors of Cytochrome P450 3A4

, 5(5): 415 - 442

Shufeng Zhou, Eli Chan, Lee Yong Lim, Urs A. Boelsterli, Shu Chuen Li, Jiancheng Wang, Qiang Zhang, Min Huang and Anlong Xu


DOI: 10.2174/1389200043335450




Human Hepatocytes in Primary Culture: The Choice to Investigate Drug Metabolism in Man

, 5(5): 443 - 462

M. J. Gomez-Lechon, M. T. Donato, J. V. Castell and R. Jover


DOI: 10.2174/1389200043335414




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