Contents

Current Drug Metabolism, Volume 3 - Number 4

Preface

, 3(4): i

J. P. Uetrecht


DOI: 10.2174/1389200023337441




Are Chemically Reactive Metabolites Responsible for Adverse Reactions to Drugs?

, 3(4): 351 - 366

D. P. Williams, N. R. Kitteringham, D. J. Naisbitt, M. Pirmohamed, D. A. Smith and B. K. Park


DOI: 10.2174/1389200023337423




Mechanism of Idiosyncratic Drug Reactions: Reactive Metabolites Formation, Protein Binding and the Regulation of the Immune System

, 3(4): 367 - 377

C. Ju and J. P. Uetrecht


DOI: 10.2174/1389200023337333




On the Diversity of Oxidative Bioactivation Reactions on Nitrogen- Containing Xenobiotics

, 3(4): 379 - 424

Amit S. Kalgutkar, Deepak K. Dalvie, John P. O'Donnell, Timothy J. Taylor and Diana C. Sahakian


DOI: 10.2174/1389200023337360




The Metabolism and Toxicity of Quinones, Quinonimines, Quinone Methides, and Quinone-Thioethers

, 3(4): 425 - 438

Terrence J. Monks and Douglas C. Jones


DOI: 10.2174/1389200023337388




Xenobiotic Acyl Glucuronides and Acyl CoA Thioesters as Protein- Reactive Metabolites With the Potential to Cause Idiosyncratic Drug Reactions

, 3(4): 439 - 450

Urs A. Boelsterli


DOI: 10.2174/1389200023337315




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