Contents

Current Drug Metabolism, Volume 14 - Number 1

Preface

, 14(1): 1

Chandra Prakash


DOI: 10.2174/1389200211309010001




Editorial [Hot Topic Non-Animal Models Used in Drug Discovery: Drug Absorption and Metabolism Guest Editor: Hélder A. Santos]

, 14(1): 2 - 3

Helder A. Santos


DOI: 10.2174/1389200211309010002




Models to Predict Intestinal Absorption of Therapeutic Peptides and Proteins

, 14(1): 4 - 20

Filipa Antunes, Fernanda Andrade, Domingos Ferreira, Hanne Mørck Nielsen and Bruno Sarmento


DOI: 10.2174/1389200211309010004




Do the Recommended Standards for In Vitro Biopharmaceutic Classification of Drug Permeability Meet the "Passive Transport" Criterion for Biowaivers?

, 14(1): 21 - 27

Simon Zakelj, Katja Berginc, Robert Roskar, Bor Kraljic and Albin Kristl


DOI: 10.2174/1389200211309010021




Improving Oral Absorption Via Drug-Loaded Nanocarriers: Absorption Mechanisms, Intestinal Models and Rational Fabrication

, 14(1): 28 - 56

Mohammad-Ali Shahbazi and Helder A. Santos


DOI: 10.2174/1389200211309010028




Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption

, 14(1): 57 - 79

Edwin C.Y. Chow and K. Sandy Pang


DOI: 10.2174/1389200211309010057




Evaluation of the Physicochemical and Biopharmaceutical Properties of Fluoro-Indomethacin

, 14(1): 80 - 89

Michela M. Mori, Anu J. Airaksinen, Jouni T. Hirvonen, Helder A. Santos and Carla M. Caramella


DOI: 10.2174/1389200211309010080




The Mechanisms Responsible for Garlic - Drug Interactions and their In Vivo Relevance

, 14(1): 90 - 101

Katja Berginc and Albin Kristl


DOI: 10.2174/1389200211309010090




In Vitro Methods to Study the Interplay of Drug Metabolism and Efflux in the Intestine

, 14(1): 102 - 111

Sanna Siissalo and Aki T. Heikkinen


DOI: 10.2174/1389200211309010102




Precision-cut Intestinal Slices as In Vitro Tool for Studies on Drug Metabolism

, 14(1): 112 - 119

Geny M.M. Groothuis and Inge A.M. de Graaf


DOI: 10.2174/1389200211309010112




Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes

, 14(1): 120 - 136

Ramzi Shawahna, Xavier Decleves and Jean-Michel Scherrmann


DOI: 10.2174/1389200211309010120




Function and Regulation of the Cyp2a5/CYP2A6 Genes in Response to Toxic Insults in the Liver

, 14(1): 137 - 150

A’edah Abu-Bakar, Jukka Hakkola, Risto Juvonen, Minna Rahnasto-Rilla, Hannu Raunio and Matti A. Lang


DOI: 10.2174/1389200211309010137




Metabolism of the Antituberculosis Drug Ethionamide

, 14(1): 151 - 158

Nuno Vale, Paula Gomes and Helder A. Santos


DOI: 10.2174/1389200211309010151




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