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Contents

Current Drug Metabolism, Volume 13 - Number 7



Catabolic Fate and Pharmacokinetic Characterization of Trastuzumab Emtansine (T-DM1): an Emphasis on Preclinical and Clinical Catabolism

, 13(7): 901 - 910

Ben-Quan Shen, Daniela Bumbaca, Ola Saad, Qin Yue, Cinthia V. Pastuskovas, S. Cyrus Khojasteh, Jay Tibbitts, Surinder Kaur, Bei Wang, Yu-Waye Chu, Patricia M. LoRusso and Sandhya Girish


DOI: 10.2174/138920012802138598


Drug Interaction Potential of Trastuzumab Emtansine (T-DM1) Combined with Pertuzumab in Patients With HER2-Positive Metastatic Breast Cancer

, 13(7): 911 - 922

Dan Lu, Howard A. Burris III, Bei Wang, E. Claire Dees, Javier Cortes, Amita Joshi, Manish Gupta, Joo-Hee Yi, Yu-Waye Chu, Ted Shih, Liang Fang and Sandhya Girish


DOI: 10.2174/138920012802138688


De-Risking Bio-therapeutics for Possible Drug Interactions Using Cryopreserved Human Hepatocytes

, 13(7): 923 - 929

Shannon Dallas, Carlo Sensenhauser, Ameesha Batheja, Monica Singer, Maria Markowska, Cindy Zakszewski, Rao N.V.S. Mamidi, Michael McMillia, Chao Han, Honghui Zhou and Jose Silva


DOI: 10.2174/138920012802138589











Detection of EGFR Somatic Mutations in Non-Small Cell Lung Cancer (NSCLC) Using a Novel Mutant-Enriched Liquidchip (MEL) Technology

, 13(7): 1007 - 1011

Li Zhang, Huiyi Yang, Yanwei Zhao, Wenchao Liu, Shiyang Wu, Jiaying He, Xiaodi Luo, Zeyao Zhu, Jiasen Xu, Qinghua Zhou and Lifen Ren-Heidenreich


DOI: 10.2174/138920012802138660





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