Contents

Current Drug Metabolism, Volume 12 - Number 8

Editorial [Hot Topic: Modulation, Absorption and Delivery of Xenobiotics: The Synergic Role of CYP450 and P-gp Activities (Guest Editor: Nicola Antonio Colabufo)]

, 12(8): 701

Nicola Antonio Colabufo


DOI: 10.2174/138920011798357033




Modulation and Absorption of Xenobiotics: The Synergistic Role of CYP450 and P-gp Activities in Cancer and Neurodegenerative Disorders

, 12(8): 702 - 712

Carmela Inglese, Maria Grazia Perrone, Francesco Berardi, Roberto Perrone and Nicola Antonio Colabufo


DOI: 10.2174/138920011798357015




The Coordinated Role of CYP450 Enzymes and P-gp in Determining Cancer Resistance to Chemotherapy

, 12(8): 713 - 721

Amalia Azzariti, Letizia Porcelli, Anna Elisa Quatrale, Nicola Silvestris and Angelo Paradiso


DOI: 10.2174/138920011798357042




P-glycoprotein Inhibition: The Past, the Present and the Future

, 12(8): 722 - 731

Richard A.J. Darby, Richard Callaghan and Roisin M. McMahon


DOI: 10.2174/138920011798357006




Interplay of Drug Metabolizing CYP450 Enzymes and ABC Transporters in the Blood-Brain Barrier

, 12(8): 732 - 741

Xavier Decleves, Aude Jacob, Salah Yousif, Ramzi Shawahna, Sophie Potin and Jean-Michel Scherrmann


DOI: 10.2174/138920011798357024




Blood-Brain Barrier P450 Enzymes and Multidrug Transporters in Drug Resistance: A Synergistic Role in Neurological Diseases

, 12(8): 742 - 749

Chaitali Ghosh, Vikram Puvenna, Jorge Gonzalez-Martinez, Damir Janigro and Nicola Marchi


DOI: 10.2174/138920011798357051




In Silico, In Vitro and In Situ Models to Assess Interplay Between CYP3A and P-gp

, 12(8): 750 - 773

Daniel R. Mudra, Kelly E. Desino and Prashant V. Desai


DOI: 10.2174/138920011798356999




PET and SPECT Radiotracers to Assess Function and Expression of ABC Transporters In Vivo

, 12(8): 774 - 792

Severin Mairinger, Thomas Erker, Markus Muller and Oliver Langer


DOI: 10.2174/138920011798356980




Overview of SLC22A and SLCO Families of Drug Uptake Transporters in the Context of Cancer Treatments

, 12(8): 793 - 807

Murray J. Cutler and Edna F. Choo


DOI: 10.2174/138920011798357060




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