Contents

Current Drug Metabolism, Volume 12 - Number 7

Editorial [Hot topic: The Challenge of Prescribing Drugs in Older People (Guest Editors: Fabrizia Lattanzio and Andrea Corsonello)]

, 12(7): 599 - 600

Andrea Corsonello


DOI: 10.2174/138920011796504491




Age-Related Changes in Pharmacokinetics

, 12(7): 601 - 610

Shaojun Shi and Ulrich Klotz


DOI: 10.2174/138920011796504527




Age-related Changes in Pharmacodynamics: Focus on Drugs Acting on Central Nervous and Cardiovascular Systems

, 12(7): 611 - 620

Gianluca Trifiro and Edoardo Spina


DOI: 10.2174/138920011796504473




Pharmacogenetics in Geriatric Medicine: Challenges and Opportunities for Clinical Practice

, 12(7): 621 - 634

Alberto Pilotto, Francesco Panza and Davide Seripa


DOI: 10.2174/138920011796504545




Paying Attention to Pharmacokinetic and Pharmacodynamic Mechanisms to Progress in the Area of Anticholinergic Use in Geriatric Patients

, 12(7): 635 - 646

J. de Leon


DOI: 10.2174/138920011796504518




The Risk of Adverse Drug Reactions in Older Patients: Beyond Drug Metabolism

, 12(7): 647 - 651

Graziano Onder, Fabrizia Lattanzio, Miriam Battaglia, Francesco Cerullo, Roberta Sportiello, Roberto Bernabei and Francesco Landi


DOI: 10.2174/138920011796504563




The Prevention of Adverse Drug Reactions in Older Subjects

, 12(7): 652 - 657

Antonio Cherubini, Carmelinda Ruggiero, Beatrice Gasperini, Giuseppina Dell'Aquila, Maria Grazia Cupido, Elena Zampi, Elisa Zengarini, Hao Nguyen Nguyen, Rocco Serra, Andrea Corsonello and Fabrizia Lattanzio


DOI: 10.2174/138920011796504482




Kidney in Diabetes: from Organ Damage Target to Therapeutic Target

, 12(7): 658 - 666

Teresa Salvatore, Ornella Carbonara, Domenico Cozzolino, Roberto Torella, Rodolfo Nasti, Nadia Lascar and Ferdinando Carlo Sasso


DOI: 10.2174/138920011796504509




L-Carnitine - Metabolic Functions and Meaning in Humans Life

, 12(7): 667 - 678

Jolanta Pekala, Bozena Patkowska-Sokola, Robert Bodkowski, Dorota Jamroz, Piotr Nowakowski, Stanislaw Lochynski and Tadeusz Librowski


DOI: 10.2174/138920011796504536




RNA Interference and Amyotrophic Lateral Sclerosis

, 12(7): 679 - 683

Albert A. Rizvanov, Sukru Gulluoglu, Mehmet E. Yalvac, Andras Palotas and Rustem R. Islamov


DOI: 10.2174/138920011796504464




An Expanded, Unified Substrate Recognition Site Map for Mammalian Cytochrome P450s: Analysis of Molecular Interactions Between 15 Mammalian CYP450 Isoforms and 868 Substrates

, 12(7): 684 - 700

Alexander Zawaira, Lim Yen Ching, Lauren Coulson, Jonathan Blackburn and Yap Chun Wei


DOI: 10.2174/138920011796504554




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