Contents

Current Drug Metabolism, Volume 12 - Number 10

Editorial [Hot Topic: Biomarkers of Chemotherapeutics Efficacy and Toxicity in Colorectal Cancer (Guest Editor: Amalia Azzariti)]

, 12(10): 917

Amalia Azzariti


DOI: 10.2174/138920011798062319




Pharmacokinetic and Metabolism Determinants of Fluoropyrimidines and Oxaliplatin Activity in Treatment of Colorectal Patients

, 12(10): 918 - 931

Antonio Gnoni, Antonio Russo, Nicola Silvestris, Evaristo Maiello, Angelo Vacca, Ilaria Marech, Gianmauro Numico, Angelo Paradiso, Vito Lorusso and Amalia Azzariti


DOI: 10.2174/138920011798062300




Pharmacokinetic and Pharmacogenetic Predictive Markers of Irinotecan Activity and Toxicity

, 12(10): 932 - 943

Antonello Di Paolo, Guido Bocci, Marialuisa Polillo, Marzia Del Re, Teresa Di Desidero, Marianna Lastella and Romano Danesi


DOI: 10.2174/138920011798062283




Predicting Efficacy and Toxicity in the Era of Targeted Therapy: Focus on Anti-EGFR and Anti-VEGF Molecules

, 12(10): 944 - 955

Michele Caraglia, Daniele Santini, Giuseppe Bronte, Sergio Rizzo, Giovanni Sortino, Giovam Battista Rini, Gaetana Di Fede and Antonio Russo


DOI: 10.2174/138920011798062346




DNA Copy Number Profiles Correlate with Outcome in Colorectal Cancer Patients Treated with Fluoropyrimidine/Antifolate-based Regimens

, 12(10): 956 - 965

Leticia G. Leon, Elisa Giovannetti, Kees Smid, Bart P.P. van Houte, Axel R. Hanauske, Giuseppe Giaccone and Godefridus J. Peters


DOI: 10.2174/138920011798062337




Alternative Spliced Variants as Biomarkers of Colorectal Cancer

, 12(10): 966 - 974

Qian Yi and Liling Tang


DOI: 10.2174/138920011798062355




The Impact of Folate Status on the Efficacy of Colorectal Cancer Treatment

, 12(10): 975 - 984

Letizia Porcelli, Yehuda G. Assaraf, Amalia Azzariti, Angelo Paradiso, Gerrit Jansen and Godefridus J. Peters


DOI: 10.2174/138920011798062274




Clinical Pharmacokinetic and Metabolism of PET Radiotracers for Imaging P-glycoprotein in Chemoresistant Tumor of Colorectal Cancer

, 12(10): 985 - 988

Mariangela Cantore, Elena Capparelli, Francesco Berardi, Roberto Perrone and Nicola Antonio Colabufo


DOI: 10.2174/138920011798062292




Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine

, 12(10): 989 - 996

Thomas Efferth and Bernd Kaina


DOI: 10.2174/138920011798062328




Humanized Transgenic Mouse Models for Drug Metabolism and Pharmacokinetic Research

, 12(10): 997 - 1006

Hong-Wu Shen, Xi-Ling Jiang, Frank J. Gonzalez and Ai-Ming Yu


DOI: 10.2174/138920011798062265




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