Contents

Current Drug Metabolism, Volume 11 - Number 9

Editorial [Hot topic: Role of Intestinal Transporters and Metabolism in the Oral Absorption of Drugs and Prodrugs (Guest Editor: Manthena V. Varma)]

, 11(9): 715

Manthena Varma


DOI: 10.2174/138920010794328878




Interplay of Metabolism and Transport in Determining Oral Drug Absorption and Gut Wall Metabolism: A Simulation Assessment Using the “Advanced Dissolution, Absorption, Metabolism (ADAM)” Model

, 11(9): 716 - 729

A. S. Darwich, S. Neuhoff, M. Jamei and A. Rostami-Hodjegan


DOI: 10.2174/138920010794328913




Targeting Intestinal Transporters for Optimizing Oral Drug Absorption

, 11(9): 730 - 742

Manthena V. Varma, Catherine M. Ambler, Mohammad Ullah, Charles J. Rotter, Hao Sun, John Litchfield, Katherine S. Fenner and Ayman F. El-Kattan


DOI: 10.2174/138920010794328850




PBPK Modeling of Intestinal and Liver Enzymes and Transporters in Drug Absorption and Sequential Metabolism

, 11(9): 743 - 761

Jianghong Fan, Shu Chen, Edwin C.Y. Chow and K. Sandy Pang


DOI: 10.2174/138920010794328931




Predicting Drug – Drug Interactions Involving the Inhibition of Intestinal CYP3A4 and P-Glycoprotein

, 11(9): 762 - 777

Tatsuhiko Tachibana, Motohiro Kato, Junichi Takano and Yuichi Sugiyama


DOI: 10.2174/138920010794328922




Influence of Dietary Substances on Intestinal Drug Metabolism and Transport

, 11(9): 778 - 792

Christina S. Won, Nicholas H. Oberlies and Mary F. Paine


DOI: 10.2174/138920010794328869




The Role of Intestinal Carboxylesterase in the Oral Absorption of Prodrugs

, 11(9): 793 - 805

Teruko Imai and Kayoko Ohura


DOI: 10.2174/138920010794328904




Current In Vitro High Throughput Screening Approaches to Assess Nuclear Receptor Activation

, 11(9): 806 - 814

Judy L. Raucy and Jerome M. Lasker


DOI: 10.2174/138920010794328896




Metabolism of Benzodiazepine and Non-Benzodiazepine Anxiolytic-Hypnotic Drugs: an Analytical Point of View

, 11(9): 815 - 829

Roberto Mandrioli, Laura Mercolini and Maria Augusta Raggi


DOI: 10.2174/138920010794328887




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