Contents

Current Drug Discovery Technologies, Volume 9 - Number 3

Editorial

Editorial: [Hot Topic: Novel Technologies for Developing Clinically Useful Hemoglobin-Based Oxygen Carriers (Guest Editor: Chi-Ming Hai)]

, 9(3): 157

Chi-Ming Hai


DOI: 10.2174/157016312802650788




Crosslinked, Polymerized, and PEG-Conjugated Hemoglobin-Based Oxygen Carriers: Clinical Safety and Efficacy of Recent and Current Products

, 9(3): 158 - 165

Jonathan S. Jahr, Arezou Sadighi Akha and Randall J. Holtby


DOI: 10.2174/157016312802650742




Microcirculation and NO-CO Studies of a Natural Extracellular Hemoglobin Developed for an Oxygen Therapeutic Carrier

, 9(3): 166 - 172

Amy G. Tsai, Marcos Intaglietta, Hiromi Sakai, Eric Delpy, Christophe Drieu La Rochelle, Morgane Rousselot and Franck Zal


DOI: 10.2174/157016312802650814




ATP-Adenosine-Glutathione Cross-Linked Hemoglobin as Clinically Useful Oxygen Carrier

, 9(3): 173 - 187

Jan Simoni, Grace Simoni, Donald E. Wesson and Mario Feola


DOI: 10.2174/157016312802650797




Present Situation of the Development of Cellular-Type Hemoglobin-Based Oxygen Carrier (Hemoglobin-Vesicles)

, 9(3): 188 - 193

Hiromi Sakai


DOI: 10.2174/157016312802650805




Adverse HBOC-Endothelial Dysfunction Synergism: A Possible Contributor to Adverse Clinical Outcomes?

, 9(3): 194 - 203

George P. Biro


DOI: 10.2174/157016312802650733




Systems Biology of HBOC-Induced Vasoconstriction

, 9(3): 204 - 211

Chi-Ming Hai


DOI: 10.2174/157016312802650751




Practical Considerations in the Development of Hemoglobin-Based Oxygen Therapeutics

, 9(3): 212 - 223

Hae Won Kim and Timothy N. Estep


DOI: 10.2174/157016312802650779




Hemoglobin Encapsulated Poly(Ethylene Glycol) Surface Conjugated Vesicles Attenuate Vasoactivity of Cell-Free Hemoglobin

, 9(3): 224 - 234

Pedro Cabrales, Shahid Rameez and Andre F.Palmer


DOI: 10.2174/157016312802650760




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