Contents

Current Drug Discovery Technologies, Volume 3 - Number 2

The Nuclear Overhauser Effect in the Lead Identification Process Pharmacophore Models

, 3(2): 91 - 100

Marilisa Leone, Hudson H. Freeze, Chui Sien Chan and Maurizio Pellecchia


DOI: 10.2174/157016306778108884




Mechanism Study of N-Dephenylation Mediated through a N-para-Hydroxy Metabolite

, 3(2): 101 - 114

Jianyao Wang, William DeMaio, Appavu Chandrasekaran, Li Shen, Alvin C. Bach II, JoAnn Scatina and Rasmy Talaat


DOI: 10.2174/157016306778108901




NMR-Based Quality Control Approach for the Identification of False Positives and False Negatives in High Throughput Screening

, 3(2): 115 - 124

Claudio Dalvit, Dannica Caronni, Nicola Mongelli, Marina Veronesi and Anna Vulpetti


DOI: 10.2174/157016306778108875




Novel Anti-bacterials Against MRSA: Synthesis of Focussed Combinatorial Libraries of Tri-Substituted 2(5H)-Furanones

, 3(2): 125 - 134

Eric Lattmann, Nison Sattayasai, Carl S. Schwalbe, Suwanna Niamsanit, David C. Billington, Pornthip Lattmann, Christopher A. Langley, Harjit Singh and Simon Dunn


DOI: 10.2174/157016306778108857




Selective Targeting of Liposomes to Macrophages Using a Ligand with High Affinity for the Macrophage Scavenger Receptor Class A

, 3(2): 135 - 144

Patrick C.N. Rensen, J.C. Emile Gras, Eva K. Lindfors, Ko Willems van Dijk, J. Wouter Jukema, Theo J.C. van Berkel and Erik A.L. Biessen


DOI: 10.2174/157016306778108893




Protein Conformational Diseases: From Mechanisms to Drug Designs

, 3(2): 145 - 153

Jin-Chung Lin and Hsuan-Liang Liu


DOI: 10.2174/157016306778108866




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