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Current Chemical Biology

Volume 14, 4 Issues, 2020
ISSN: 1872-3136 (Online)
ISSN: 2212-7968 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Chemical Biology aims to publish full-length and mini reviews as well as research papers on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Chemical Mechanisms of Biological Systems (Mechanisms of drug design; Molecular recognition; Enzyme inhibition mechanisms; Chemical mechanisms of biological functions; Molecular machines; Chemical ecology; Metal ions in biological systems; Metalloenzymes; Chemical mechanisms, proteomics and metabonomics; Chemical imaging; Small molecule-biological target interactions; Biologically active natural products; Elucidation of biosynthetic pathways; and Simulation and modeling of biomolecules).

Current Chemical Biology

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Volume 14

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Number 2



Biography   Open Access



Review Article



Research Article



Research Article



Research Article



Research Article



Research Article



Articles Ahead of Print

Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease


Iván R Vega-Valdez, Melvin N Rosalez, José M Santiago-Quintana, Eunice D Farfán-García and Marvin A Soriano-Ursúa*


DOI: 10.2174/2212796814999201102195651
View Abstract


Cyclin Dependent Kinase as a Novel Therapeutic Target: An Endless Story


Ahmed Mohamed Etman, Sherif Sabry Abdel Mageed, Mohamed Ahmed Ali and Mahmoud Abd El Monem El Hassab*


DOI: 10.2174/2212796814999201123194016
View Abstract


Anticarcinogenic Effects of Capsaicin-Loaded Nanoparticles on In Vitro Hepatocellular Carcinoma


Noha M Hazem*, Wagdi F ElKashef, Ibrahim M El-Sherbiny, Ahmed A Emam, Dalia Shaalan and Mohamed Sobh


DOI: 10.2174/2212796814999201116211648
View Abstract


Differential Metabolites Markers from Trunking and Stressed Non-Trunking Sago Palm (Metroxylon sagu Rottb.)


Hasnain Hussain*, Wei-Jie Yan, Zainab Ngaini, Norzainizul Julaihi, Rina Tommy and Showkat Ahmad Bhawani


DOI: 10.2174/2212796814999200930120925
View Abstract


Serum Biomarkers for Noninvasive Diagnosis of Liver Diseases: How laudable are these tools?


Ankita Singh, Vipul Ranjan, Rina Das*, Karun Bhatti, Dinesh Kumar Mehta and Ram Mohan Chidurala


DOI: 10.2174/2212796814999201111204639
View Abstract


Molecular Processes Involved in Pancreatic Cancer and Therapeutics


Subhajit Makar, Abhrajyoti Ghosh, Divya, Shalini Shivhare, Ashok Kumar and Sushil K. Singh*


DOI: 10.2174/2212796814999201008130819
View Abstract


Dose Formulation, Biodistribution and PET Imaging Studies of a First-In-Class Fluorine-18 Organophosphorus Cholinesterase Inhibitor Tracer in Rat


Kiel D. Neumann, Joseph E. Blecha, Chih-Kai Chao, Tony Huynh, Kurt R. Zinn, Henry F. VanBrocklin, Charles M. Thompson and John M. Gerdes*


DOI: 10.2174/2212796814999201005195509
View Abstract


Peaceful Existence of Tumor Cells with their Non-malignant Neighbors: The Trade of Tumor Cells with Tumor Microenvironment


Amirhosein Maali, Mohammad Sarfi, Mohammad Mirzakhani, Golnaz Goodarzi, Mahmoud Maniati, Sadra Samavarchi Tehrani and Durdi Qujeq*


DOI: 10.2174/2212796814999200925162943
View Abstract


DFT Study and Synthesis of Novel Bioactive Bispyrazole using Mg/Al-LDH as a Solid Base Catalyst


Soufiane Akhramez, Youness Achour, Mustapha Dib, Lahoucine Bahsis*, Hajiba Ouchetto, Abderrafia Hafid, Mostafa Khouili* and Mohammadine El Haddad


DOI: 10.2174/2212796814999200918175018
View Abstract


Evaluation of Snake Venom’s PhospholipaseA2 Enzyme Inhibition Activity of Cyphostemma adenocoule


Atul Kaushik*, Teamrat Solomon Tesfai, Daniel Kidane Barkh, Furtuna Kahsu Ghebremeskel, Habtom Ghebru Zerihun and Saron Woldegabir Woldeab


DOI: 10.2174/2212796814999200917114914
View Abstract


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Open Access Articles

POCl3 Mediated Syntheses, Pharmacological Evaluation and Molecular Docking Studies of Some Novel Benzofused Thiazole Derivatives as a Potential Antioxidant and Anti-inflammatory Agents

, 2020; 14(1): 58 - 68

Dattatraya G. Raut*, Sandeep B. Patil, Prafulla B. Choudhari, Vikas D. Kadu, Anjana S. Lawand, Mahesh G. Hublikar and Raghunath B. Bhosale





Cytotoxicity Evaluation of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines Against Cancerous Liver Cells

, 2020; 14(1): 38 - 47

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *





Hsp90 as Drug Target Against Bacterial and Fungal Infections

, 2020; 14: 1 - 16 (E-Pub Ahead of Print)

Zehra Edis*, Samir Haj Bloukh, Mohammad Waseemul Islam and Sabreena Ait Gacem




Docking Simulations Exhibit Bortezomib and other Boron-containing Peptidomimetics as Potential Inhibitors of SARS-CoV-2 Main Protease

, 2020; 14: 1 - 9 (E-Pub Ahead of Print)

Iván R Vega-Valdez, Melvin N Rosalez, José M Santiago-Quintana, Eunice D Farfán-García and Marvin A Soriano-Ursúa*









Functional Characterization of Chitin and Chitosan

, 2009; 3(2): 203 - 230

Inmaculada Aranaz, Marian Mengibar, Ruth Harris, Ines Panos, Beatriz Miralles, Niuris Acosta, Gemma Galed and Angeles Heras




Cause of Chirality Consensus

, 2008; 2(2): 153 - 158

Salla Jaakkola, Vivek Sharma and Arto Annila






Most Cited Articles

Review Article

Endogenous repair system of oxidative damage of DNA

, 2019; 13(2): 110-119.

Anmol Sharma, Pawan Gupta and Pranav Kumar Prabhakar*


DOI: 10.2174/2212796813666190221152908



Research Article

RNAi-mediated resistance against plant parasitic nematodes of wheat plants obtained in vitro using bioregulators of microbiological origin

, 2019; 13(1): 73-89.

Victoria A. Tsygankova *, Yaroslav V. Andrusevich, Elena N. Shysha, Lyudmila O. Biliavska, Tatyana O. Galagan, Anatoly P. Galkin, Alla I. Yemets , Galina A. Iutynska and Yaroslav B. Blume


DOI: 10.2174/2212796812666180507130017





Research Article

Antimicrobial activity of highly fluorinated thiocarbamates and dithiocarbamates

, 2019; 13(2): 120-128.

Amal Thebti, Ines Chniti, Med Abderrahmane Sanhoury*, Ikram Chehidi, Hadda Imene Ouzari and Abdellatif Boudabous


DOI: 10.2174/2212796812666180907153901



Research Article

Thermostabilization of BSA in TMAO water mixtures by infrared spectroscopy

, 2019; 13(1): 49-59.

Arianna Adamo, Emanuele Calabrò and Salvatore Magazù


DOI: 10.2174/2212796812666180613082040



Research Article

POCL<inf>3</inf> mediated syntheses, pharmacological evaluation and molecular docking studies of some novel benzofused thiazole derivatives as a potential antioxidant and anti-inflammatory agents

, 2020; 14(1): 58-68.

Dattatraya G. Raut*, Sandeep B. Patil, Prafulla B. Choudhari, Vikas D. Kadu, Anjana S. Lawand, Mahesh G. Hublikar and Raghunath B. Bhosale


DOI: 10.2174/2212796813666191118100520


Research Article

Cytotoxicity evaluation of dimethoxy and trimethoxy indanonic spiroisoxazolines against cancerous liver cells

, 2020; 14(1): 38-47.

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *


DOI: 10.2174/2212796813666190926112807


Review Article

The role of heat shock protein-90 (HSP-90) in inflammatory disorders

, 2020; 14(1): 30-37.

Chiranjib Bhattacharjee and Lokesh Deb*


DOI: 10.2174/2212796814666200122114833


Preface

Preface

, 2020; 14(1): 3-3.

Ricardo Riguera


DOI: 10.2174/221279681401200422102421




Most Accessed Articles






Synthesis, Characterisation, Anti-Microbial Activity and Docking Studies of Novel Dispiro- Oxindolopyrrolidines

, 2009; 3(1): 112-123.

Adukamparai R. Suresh Babu, Raghavachary Raghunathan, Kuppamuthu Kumaresan and Nanjian Raaman


DOI: 10.2174/2212796810903010112


MicroRNA Regulation of Programmed Cell Death Pathways in Cancer

, 2012; 6(1): 53-59.

Miao Ming, Xu Zhao, Zi-yi Zhao, Bo Liu and Jin-ku Bao


DOI: 10.2174/2212796811206010053



Cytotoxicity Evaluation of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines Against Cancerous Liver Cells

, 2020; 14(1): 38-47.

Ahmad Abolhasani , Fatemeh Heidari , Somayeh Noori, Shokoufeh Mousavi and Hoda Abolhasani *


DOI: 10.2174/2212796813666190926112807




Editor-in-Chief

Claudio Santi
Department of Pharmaceutical Sciences
University of Perugia
Perugia
(Italy)
Biography
View Full Editorial Board

Journal History

Current Chemical Biology was launched in 2007. Dr. Claudio Santi serves as the Editor-in-Chief of the journal.

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