Contents

Current Cancer Drug Targets, Volume 13 - Number 3

Editorial (Hot Topic: PI3K/AKT and mTOR/p70S6K1 Signaling Pathways in Human Cancer)

, 13(3): 233

Bing-Hua Jiang


DOI: 10.2174/1568009611313030001




Diverse Mechanisms of AKT Pathway Activation in Human Malignancy

, 13(3): 234 - 244

Mitchell Cheung and Joseph R. Testa


DOI: 10.2174/1568009611313030002




Oxygen-independent Regulation of HIF-1: Novel Involvement of PI3K/ AKT/mTOR Pathway in Cancer

, 13(3): 245 - 251

Faton Agani and Bing-Hua Jiang


DOI: 10.2174/1568009611313030003




Roles of EGFR, PI3K, AKT, and mTOR in Heavy Metal-Induced Cancer

, 13(3): 252 - 266

Richard L. Carpenter and Bing-Hua Jiang


DOI: 10.2174/1568009611313030004




Targeting the mTOR Pathway in Tumor Malignancy

, 13(3): 267 - 277

Hengmiao Cheng, Marlena Walls, Sangita M. Baxi and Min-Jean Yin


DOI: 10.2174/1568009611313030005




IDO+ DCs and Signalling Pathways

, 13(3): 278 - 288

Yue Wang, Bao-Hong Yang, Hui Li, Shui Cao, Xiu-Bao Ren and Jin-Pu Yu


DOI: 10.2174/15680096113139990073




Novel HSP90 Inhibitor NVP-AUY922 Enhances the Anti-tumor Effect of Temsirolimus Against Oral Squamous Cell Carcinoma

, 13(3): 289 - 299

Tatsuo Okui, Tsuyoshi Shimo, Takuya Fukazawa, Nur Mohammad Monsur Hassan, Tatsuki Honami, Soichiro Ibaragi, Munenori Takaoka, Yoshio Naomoto and Akira Sasaki


DOI: 10.2174/1568009611313030007




Targeting Tyrosine Kinase Receptors in Hepatocellular Carcinoma

, 13(3): 300 - 312

Jordi Muntane, Angel J. De la Rosa, Fernando Docobo, Rocio Garcia-Carbonero and Francisco J. Padillo


DOI: 10.2174/15680096113139990075




Novel Agents, Combinations and Sequences for the Treatment of Advanced Renal Cell Carcinoma: When is the Revolution Coming?

, 13(3): 313 - 325

Matteo Santoni, Mimma Rizzo, Luciano Burattini, Rossana Berardi, Giacomo Carteni and Stefano Cascinu


DOI: 10.2174/1568009611313030009




P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future Perspectives

, 13(3): 326 - 346

Ziyad Binkhathlan and Afsaneh Lavasanifar


DOI: 10.2174/15680096113139990076




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