Contents

Current Cancer Drug Targets, Volume 10 - Number 8

EDITORIAL [Hot topic: RAS - A Central Feature in Cancer Targeted Therapy (Guest Editor: Balazs Gyorffy)

, 10(8): 797 - 798

Balazs Gyorffy


DOI: 10.2174/156800910793358023




Predictive Molecular Markers of Response to Epidermal Growth Factor Receptor(EGFR) Family-Targeted Therapies

, 10(8): 799 - 812

Sarah Barton, Naureen Starling and Charles Swanton


DOI: 10.2174/156800910793357925




KRAS Mutation Testing of Colorectal Cancer for Anti-EGFR Therapy: Dogmas Versus Evidence

, 10(8): 813 - 823

J. Timar, B. Hegedus and E. Raso


DOI: 10.2174/156800910793357989




Strategies for Overcoming Inherent and Acquired Resistance to EGFR Inhibitors by Targeting Downstream Effectors in the RAS/PI3K Pathway

, 10(8): 824 - 833

A. J. Weickhardt, N. C. Tebbutt and J. M. Mariadason


DOI: 10.2174/156800910793357961




RAS Pathways in Prostate Cancer - Mediators of Hormone Resistance?

, 10(8): 834 - 839

H. C. Whitaker and D. E. Neal


DOI: 10.2174/156800910793358005




Targeting Ras-RAF-ERK and its Interactive Pathways as a Novel Therapy for Malignant Gliomas

, 10(8): 840 - 848

H.-W. Lo


DOI: 10.2174/156800910793357970




The Crosstalk of RAS with the TGF-β Family During Carcinoma Progression and its Implications for Targeted Cancer Therapy

, 10(8): 849 - 857

M. Grusch, M. Petz, T. Metzner, D. Ozturk, D. Schneller and W. Mikulits


DOI: 10.2174/156800910793357943




Biomarkers Downstream of RAS: A Search for Robust Transcriptional Targets

, 10(8): 858 - 868

B. Gyorffy and R. Schafer


DOI: 10.2174/156800910793357916




Ras-Induced Senescence and its Physiological Relevance in Cancer

, 10(8): 869 - 876

T. DiMauro and G. David


DOI: 10.2174/156800910793357998




EDITORIAL [Hot topic: New Therapeutic Advances and Perspectives in Tumour Angiogenesis (Guest Editor: Eddy Pasquier)]

, 10(8): 877 - 878

Eddy Pasquier and Nicolas Andre


DOI: 10.2174/156800910793358032




Anti-Angiogenic Therapies for Children with Cancer

, 10(8): 879 - 889

N. Andre, A. Verschuur, J. Rossler and J. Sterba


DOI: 10.2174/156800910793357899




Implication of Heat Shock Protein 90 (HSP90) in Tumor Angiogenesis: A Molecular Target for Anti-Angiogenic Therapy?

, 10(8): 890 - 897

K. Staufer and O. Stoeltzing


DOI: 10.2174/156800910793357934




Histone Deacetylases: Anti-Angiogenic Targets in Cancer Therapy

, 10(8): 898 - 913

D. Mottet and V. Castronovo


DOI: 10.2174/156800910793358014




Endothelial Progenitor Cells: Hope Beyond Controversy

, 10(8): 914 - 921

E. Pasquier and S. Dias


DOI: 10.2174/156800910793358041




Inhibition of Membrane Complement Inhibitor Expression (CD46, CD55, CD59) by siRNA Sensitizes Tumor Cells to Complement Attack In Vitro

, 10(8): 922 - 931

N. Geis, S. Zell, R. Rutz, W. Li, T. Giese, S. Mamidi, S. Schultz and M. Kirschfink


DOI: 10.2174/156800910793357952




Tumor-Targeted Inhibition by a Novel Strategy - Mimoretrovirus Expressing siRNA Targeting the Pokemon Gene

, 10(8): 932 - 941

Z. Tian, H. Wang, Z. Jia, J. Shi, J. Tang, L. Mao, H. Liu, Y. Deng, Y. He, Z. Ruan, J. Li, Y. Wu and B. Ni


DOI: 10.2174/156800910793357907




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