Articles Ahead of Print

The Biological Activity of the Novel Vinca Alkaloids 4-chlorochablastine und 4-chlorochacristine


Gracia Montag, Helga Stopper, Quoc Anh Ngo and Henning Hintzsche*


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Blocking IL-6/GP130 Signaling Inhibits Cell Viability/Proliferation, Glycolysis, and Colony Forming Activity in Human Pancreatic Cancer Cells


Xiang Chen, Jilai Tian, Gloria H. Su and Jiayuh Lin*


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Efficacy and Safety of Antigen-specific Immunotherapy in the Treatment of Patients with Non-small-cell Lung Cancer: A Systematic Review and Meta-analysis


Bing-Di Yan, Xiao-Feng Cong, Sha-Sha Zhao, Meng Ren, Zi-Ling Liu, Zhi Li, Chen Chen and Lei Yang*


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Cutaneous Application of Celecoxib for Inflammatory and Cancer Diseases


Oliesia Gonzales Quinones and Maria Bernadete Riemma Pierre*


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The Anti-malarial Drug Artesunate Blocks Wnt/β-catenin Pathway and Inhibits Growth, Migration and Invasion of Uveal Melanoma Cells


Lei Zheng and Jingxuan Pan


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Role of MicroRNAs in Treatment Response in Prostate Cancer


Anshuli Razdan, Paul de Souza* and Tara Laurie Roberts


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Role of miR-193a in Cancer: Complexity and Factors Control the Pattern of its Expression


Afraa Mamoori, Vinod Gopalan and Alfred K-Y Lam*


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Noxa: Role in Cancer Pathogenesis and Treatment


Rami Z. Morsi, Rouba Hage-Sleiman, Hadile Kobeissy and Ghassan Dbaibo*


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Interrupting the FGF19-FGFR4 Axis to Therapeutically Disrupt Cancer Progression


Liwei Lang, Austin Y Shull and Yong Teng*


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Parp Inhibitors for the Treatment of Ovarian Cancer


Laura Cortesi, Angela Toss* and Iole Cucinotto


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Metastatic Site Location Influences the Diagnostic Accuracy of ctDNA EGFR- Mutation Testing in NSCLC Patients: a Pooled Analysis


Francesco Passiglia, Sergio Rizzo, Christian Rolfo, Antonio Galvano, Enrico Bronte, Lorena Incorvaia, Angela Listi, Nadia Barraco, Marta Castiglia, Valentina Calo, Viviana Bazan and Antonio Russo*


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Novel Homeodomain Transcription Factor Nkx2.2 in the Brain Tumor Development


Mubeena PM Mariyath, Mehdi Hayat Shahi*, Shirin Farheen, Mohd Tayyab, Nabeela Khanam and Asif Ali


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SOCS6 Functions as a Tumor Suppressor by Inducing Apoptosis and Inhibiting Angiogenesis in Human Prostate Cancer


Dongbo Yuan*, Wei Wang*, Jiaming Su*, Yongqiang Zhang, Boshi Luan, Haofu Rao, Tianfei Cheng, Wei Zhang, Shiwei Xiao, Mingsheng Zhang, Fu-Neng Jiang, Zhaolin Sun, Zhenyu Jia, Wei-De Zhong and Jianguo Zhu


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Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update


Shirin Eyvazi, Safar Farajnia*, Siavoush Dastmalchi, Farzad Kanipour, Habib Zarredar and Mojgan Bandehpour


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Molecular Mechanisms of Resistance in Testicular Germ Cell Tumors - Clinical Implications


Katarina Kalavska, Vincenza Conteduca, Ugo De Giorgi and Michal Mego*


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Anticancer Properties of Essential Oils: An Overview


Milene Aparecida Andrade, Mariana Aparecida Braga, Pedro Henrique Souza Cesar, Marcus Vinicius Cardoso Trento, Mariana Araujo Esposito and Lucilene Fernandes Silva*


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Targeting FGFR with BGJ398 in Breast Cancer: Effect on Tumor Growth and Metastasis


Ana Sahores, Maria May, Gonzalo Sequeira, Cynthia Fuentes, Britta Jacobsen, Claudia Lanari and Caroline Ana Lamb*


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AR Copy Number and AR Signaling-directed Therapies in Castrationresistant Prostate Cancer


Samanta Salvi*, Vincenza Conteduca, Cristian Lolli, Sara Testoni, Valentina Casadio, Andrea Zaccheroni, Lorena Rossi, Salvatore Luca Burgio, Cecilia Menna, Giuseppe Schepisi and Ugo De Giorgi


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A High-throughput Quantitative Expression Analysis of Cancer-related Genes in Human HepG2 Cells in Response to Limonene, a Potential Anticancer Agent


Rand R. Hafidh*, Saba Z. Hussein, Mohammed Q. MalAllah, Ahmed S. Abdulamir and Fatimah Abu Bakar


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Autophagy as a Potential Therapeutic Target in Breast Cancer Treatment


Natalia Lisiak*, Ewa Toton and Maria Rybczynska


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Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity


Jie An and M. Saeed Sheikh*


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Degradation of Androgen Receptor through Small Molecules for Prostate Cancer


Raoling Ge, Xi Xu, Pengfei Xu, Lei Li, Zhiyu Li* and Jinlei Bian


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Development of Drug Targeting and Delivery in Cervical Cancer


Urvashi Aggarwal, Amit Kumar Goyal and Goutam Rath*


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Ponatinib: A Review of Efficacy and Safety


Fulvio Massaro, Matteo Molica and Massimo Breccia*


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Clinical Evidence on the Magnitude of Change in Growth Pathway Activity in Relation to Tamoxifen Resistance is Required


Sepideh Mansouri, Leila Farahmand, Azin Teymourzadeh and Keivan Majidzadeh-A*


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Aldose Reductase Inhibitor, Fidarestat Prevents High-fat Diet-induced Intestinal Polyps in ApcMin/+ Mice


Ashish Saxena, Ravinder Tammali, Kota V Ramana and Satish K. Srivastava*


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Evaluation of Anti-cancer Activity of Stilbene and Methoxydibenzo[b,f] oxepin Derivatives


Damian Garbicz , Damian Mielecki , Michał Wrzesiński , Tomasz Pilżys, Michał Marcinkowski , Jan Piwowarski , Janusz Dębski, Ewelina Palak, Przemysław Szczeciński, Hanna Krawczyk and Elżbieta Grzesiuk*


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An Update on Circumventing Multidrug Resistance in Cancer by Targeting P-Glycoprotein


Xiaoqian Yang, Xiaoduan Li, Zhenfeng Duan and Xipeng Wang*


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The Structural Bioinformatics Analysis of Biophenolic Lignan-Estrogen Receptor Interaction


Farzaneh Mohamadyar-Toupkanlou*, Mina Esfandiari, Mahshid Sadat Kashef-Saberi, Mahboubeh Kabiri Renani and Masoud Soleimani


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The Safety, Efficacy and Therapeutic Potential of Histone Deacetylase Inhibitors with Special Reference to Panobinostat in Gastrointestinal Tumors: A Review of Preclinical and Clinical Studies


Avineesh Singh, Preeti Patel, Jageshwar, Vijay Kumar Patel, Deepak Kumar Jain, M Kamal and Harish Rajak*


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p53-Mdm2 Interaction Inhibitors as Novel Nongenotoxic Anticancer Agents


Surendra Kumar Nayak*, Gopal L. Khatik, Rakesh Narang, Vikramdeep Monga and Harish Kumar Chopra


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Therapeutic Approaches for the Treatment of Epidermal Growth Factor Receptor Mutated Lung Cancer


Dhaval Sanchala, Lokesh K Bhatt* and Kedar S Prabhavalkar


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Regulation of MicroRNAs by Phytochemicals: A Promising Strategy for Cancer Chemoprevention


Sadegh Babashah*, Babak Bakhshinejad, Maryam Tahmasebi Birgani , Katayoon Pakravan and William C Cho*


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JQ1, a BET Inhibitor, Synergizes with Cisplatin and Induces Apoptosis in Highly Chemoresistant Malignant Pleural Mesothelioma Cells


Ilaria Zanellato*, Donato Colangelo and Domenico Osella


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Significant Role of MUC1 in Development of Resistance to Currently Existing Anti-cancer Therapeutic Agents


Leila Farahmand, Parnaz Merikhian, Neda Jalili, Behrad Darvishi and Keivan Majidza*


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Pharmacoinformatic Approaches to Design Novel Inhibitors of Protein Kinase B Pathways in Cancer


Noreen Akhtar and Ishrat Jabeen*


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Crizotinib Versus Chemotherapy on ALK-positive NSCLC: A Systematic Review of Efficacy and Safety


Mingxia Wang, Guanqi Wang, Haiyan Ma and Baoen Shan*


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Specific Targeting of HER2-Positive Head and Neck Squamous Cell Carcinoma Line HN5 by Idarubicin-ZHER2 Affibody Conjugate


Marzieh Ghanemi, Aminollah Pourshohod, Mohammad Ali Ghaffari , Alireza kheirollah, Mansour Amin, Majid Zeinali* and Mostafa Jamalan*


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