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Endorsements

"This journal fills an important need in providing reviews, covering the moving area of new cancer drug targets."

Paul Workman
CRC Centre for Cancer Therapeutics, England

Forthcoming Special Issues

CANCER EPIGENETICS


Guest Editor(s): Aamir Ahmad
Tentative Publication Date: November, 2017
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Special Issues - In-Press
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Published Special Issues

CANCER BIOMARKERS FROM BENCH TO BEDSIDE


Guest Editor(s): BALÁZS GYŐRFFY
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Authors' Comments
"I would like to express my sincere thanks for the services by Bentham Science.
I'm really happy with my submission in your Journal and hope that I will able to continue submitting manuscripts to your journal"

Saeed Samarghandian
(Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran)


Current Cancer Drug Targets

,

Volume 18

-

Number 9



Biography   Open Access



Review Article



Review Article



Review Article

Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update

, 18(9): 857 - 868

Shirin Eyvazi, Safar Farajnia*, Siavoush Dastmalchi, Farzad Kanipour, Habib Zarredar and Mojghan Bandehpour


DOI: 10.2174/1568009618666180102102311




Review Article

AR Copy Number and AR Signaling-directed Therapies in Castrationresistant Prostate Cancer

, 18(9): 869 - 876

Samanta Salvi*, Vincenza Conteduca, Cristian Lolli, Sara Testoni, Valentina Casadio, Andrea Zaccheroni, Lorena Rossi, Salvatore Luca Burgio, Cecilia Menna, Giuseppe Schepisi and Ugo De Giorgi


DOI: 10.2174/1568009617666171122145852




Review Article



Research Article

SOCS6 Functions as a Tumor Suppressor by Inducing Apoptosis and Inhibiting Angiogenesis in Human Prostate Cancer

, 18(9): 894 - 904

Dongbo Yuan*, Wei Wang*, Jiaming Su*, Yongqiang Zhang, Boshi Luan, Haofu Rao, Tianfei Cheng, Wei Zhang, Shiwei Xiao, Mingsheng Zhang, Fu-Neng Jiang, Zhaolin Sun, Zhenyu Jia*, Wei-De Zhong* and Jianguo Zhu*


DOI: 10.2174/1568009618666180102101442




Research Article



Articles Ahead of Print


Gene Therapy and Photothermal Therapy of Layer-by-Layer Assembled AuNCs /PEI/miRNA/ HA Nanocomplexes


Li-Juan Yan, Xin-Hong Guo, Wei-Ping Wang, Yu-Rong Hu*, Shao-Feng Duan*, Ying Liu, Zhi Sun, Sheng-Nan Huang and Hui-li Li


View Abstract View on PubMed


Cordycepin Downregulates Cdk-2 to Interfere with Cell Cycle and Increases Apoptosis by Generating ROS in Cervical Cancer Cells: in vitro and in silico Study


Mousumi Tania, Jakaria Shawon, Kazi Saif, Rudolf Kiefer, Mahdi Safaei Khorram, Mohammad A Halim and Md. Asaduzzaman Khan*


View Abstract View on PubMed


In Vitro and In Vivo Antimetastatic Effects of ZSTK474 on Prostate Cancer DU145 Cells


Jie Liu, Xiao Tan, Wennan Zhao, Jing Liu, Xiaoxue Xing, Guanwei Fan, Ping Zhang, Zhe Zhang, Yuxu Zhong* and Dexin Kong*


View Abstract View on PubMed





c-Myc Inhibitor 10074-G5 Induces Murine and Human Hematopoietic Stem and Progenitor Cell Expansion and HDR Modulator Rad51 Expression


Merve Aksoz, Esra Albayrak, Galip Servet Aslan, Raife Dilek Turan, Lamia Yazgi Alyazici, Pinar Siyah, Emre Can Tusuz, Serli Canikyan, Dogacan Yucel, Neslihan Meric, Zafer Gulbas, Fikrettin Sahin and Fatih Kocabas*


View Abstract View on PubMed


Exploring Proteomic Drug Targets, Therapeutic Strategies and Protein- Protein Interactions in Cancer: Mechanistic View


Khalid Bashir Dar, Aashiq Hussain Bhat, Shajrul Amin, Syed Anjum, Bilal Ahmad Reshi, Mohammad Afzal Zargar, Akbar Masood and Showkat Ahmad Ganie*


View Abstract View on PubMed



Abstracts Ahead of Print

Targeting strategies for glucose metabolic pathways and T cells in colorectal cancer


Gang Wang, Jun-Jie Wang, Rui Guan, Yan Sun, Feng Shi, Jing Gao* and Xing-Li Fu*


View Abstract


Gender Differences in the Antioxidant Response to Oxidative Stress in Experimental Brain Tumors


María Jesús Ramírez-Expósito, María Dolores Mayas, María Pilar Carrera-González and José Manuel Martínez-Martos*


View Abstract


HSF1 as a Cancer Biomarker and Therapeutic Target


Richard L. Carpenter* and Yesim Gokmen-Polar


View Abstract



Targeting Upstream Kinases of STAT3 in Human Medulloblastoma cells


Jia Wei, Ling Ma, Chenglong Li, Christopher R. Pierson, Jonathan L. Finlay and Jiayuh Lin*


View Abstract



Oral Drug Delivery Systems for Ulcerative Colitis Therapy: A Comparative Study with Microparticles and Nanoparticles


Panpan Ma, Xiaoying Si, Qiubing Chen, Lijun Ma, Meili Hou, Zhigang Xu, Yuejun Kang, Jianglin Wang* and Bo Xiao*


View Abstract



Polyploid Giant Cancer Cells (PGCCs): The Evil Roots of Cancer


Junsong Chen, Na Niu, Jing Zhang, Lisha Qi , Weiwei Shen , Krishna Vanaja Donkena, Zhenqing Feng and Jinsong Liu *


View Abstract View on PubMed


Targeting Membrane Receptors of Ovarian Cancer Cells for Therapy


Zhiquan Liang, Ziwen Lu, Yafei Zhang, Dongsheng Shang, Ruyan Li, Lanlan Liu, Zhicong Zhao, Peishan Zhang, Qiong Lin, Chunlai Feng, Yibang Zhang, Peng Liu, Zhigang Tu* and Hanqing Liu*


View Abstract


Editor's Choice


p53-Mdm2 Interaction Inhibitors as Novel Nongenotoxic Anticancer Agents

, 2018; 18(8): 749 - 772

Surendra Kumar Nayak*, Gopal L. Khatik, Rakesh Narang, Vikramdeep Monga and Harish Kumar Chopra


DOI: 10.2174/1568009617666170623111953



Regulation of MicroRNAs by Phytochemicals: A Promising Strategy for Cancer Chemoprevention

, 2018; 18(7): 640 - 651

Sadegh Babashah*, Babak Bakhshinejad, Maryam Tahmasebi Birgani, Katayoon Pakravan and William C. Cho*


DOI: 10.2174/1568009617666170623124710



Oncolytic Tanapoxvirus Expressing Interleukin-2 is Capable of Inducing the Regression of Human Melanoma Tumors in the Absence of T Cells

, 2018; 18(6): 577 - 591

Tiantian Zhang, Dennis H. Kordish, Yogesh R. Suryawanshi, Rob R. Eversole, Steven Kohler, Charles D. Mackenzie and Karim Essani*


DOI: 10.2174/1568009617666170630143931



The Real Impact of Target Therapy in Breast Cancer Patients: Between Hope and Reality

, 2018; 18(5): 480 - 498

Sebastiano Bordonaro, Massimiliano Berretta, Antonino Carmelo Tralongo, Silvia Clementi, Brigida Stanzione and Paolo Tralongo*


DOI: 10.2174/1568009617666170209100322



Cell-derived Exosomes as Promising Carriers for Drug Delivery and Targeted Therapy

, 2018; 18(4): 347 - 354

Xinyi Wang, Haiyang Zhang, Haiou Yang, Ming Bai, Tao Ning, Shuang Li, Jialu Li, Ting Deng, Guoguang Ying* and Yi Ba*


DOI: 10.2174/1568009617666170710120311



Autophagy Inhibition in Childhood Nephroblastoma and the Therapeutic Significance

, 2018; 18(3): 295 - 303

Lin-Jie Li , Yi-Long Wang, Lin-Qing Yuan, Wei-Zhong Gu, Kun Zhu, Min Yang, Duo Zhou, Yao Lv, Min-Ju Li, Zheng-Yan Zhao, Jin-Hu Wang* and Xi Chen*


DOI: 10.2174/1568009617666170330105433



Oncolytic Viruses: The Best is Yet to Come

, 2018; 18(2): 109 - 123

Chantal G. Lemay, Brian A. Keller, Robert E. Edge, Masato Abei and John C. Bell*


DOI: 10.2174/1568009617666170206111609





Open Access Articles

Linc01638 Promotes Tumorigenesis in HER2+ Breast Cancer

, 2018; 18: 1 - 7 (E-Pub Ahead of Print)

Peng Liu, Hailin Tang, Jiali Wu, Xingsheng Qiu, Yanan Kong, Lijuan Zhang, Xinhua Xie* and Xiangsheng Xiao*





Identification of Novel Agents for the Treatment of Brain Metastases of Breast Cancer

, 2017; 17(5): 479 - 485

Vinay K. Venishetty, Werner J. Geldenhuys, Tori B. Terell-Hall, Jessica I.G. Griffith, Gregory R. Sondag, Fayez F. Safadi and Paul R. Lockman*




Recent Advances in Site Specific Conjugations of Antibody Drug Conjugates (ADCs)

, 2016; 16(6): 469 - 479

Wenlong Gao, Jingxin Zhang, Jun Xiang, Lei Zhang, Chengbin Wu, Pradeep K. Dhal and Bo Chen









Platycodin D Induces Tumor Growth Arrest by Activating FOXO3a Expression in Prostate Cancer in vitro and in vivo

, 2014; 14(9): 860 - 871

Rui Zhou, Zongliang Lu, Kai Liu, Jing Guo, Jie Liu, Yong Zhou, Jian Yang, Mantian Mi and Hongxia Xu




Pleiotropic Role of HSF1 in Neoplastic Transformation

, 2014; 14(2): 144 - 155

Natalia Vydra, Agnieszka Toma and Wieslawa Widlak






β-Catenin Knockdown in Liver Tumor Cells by a Cell Permeable Gamma Guanidine-based Peptide Nucleic Acid

, 2013; 13(8): 867 - 878

Evan Delgado, Raman Bahal, Jing Yang, Jung M. Lee, Danith H Ly and Satdarshan P. S. Monga




Signal Transduction in Human Cutaneous Melanoma and Target Drugs

, 2013; 13(8): 843 - 866

Anatoly B. Uzdensky, Svetlana V. Demyanenko and Mikhail Y. Bibov





Most Cited Articles

Epi-Drugs and Epi-miRs: Moving Beyond Current Cancer Therapies

, 2016; 16(9): 773-788.

Reza Salarinia, Amirhossein Sahebkar, Mostafa Peyvandi, Hamid Reza Mirzaei, Mahmoud Reza Jaafari, Maryam Matbou Riahi, Hamed Ebrahimnejad, Javid Sadri Nahand, Jamshid Hadjati, Mobina Ostadi Asrami, Sara Fadaei, Rasoul Salehi and Hamed Mirzaei


DOI: 10.2174/1568009616666151207110143




Indoleamine 2,3-dioxygenase (IDO): Biology and Target in Cancer Immunotherapies

, 2016; 16(9): 755-764.

Senthamil R. Selvan, John P. Dowling, William K. Kelly and Jianqing Lin


DOI: 10.2174/1568009615666151030102250


Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma

, 2016; 16(3): 261-274.

Marilù Fanelli, Claudia Maria Hattinger, Serena Vella, Elisa Tavanti, Francesca Michelacci, Beth Gudeman, Daryl Barnett, Piero Picci and Massimo Serra


DOI: 10.2174/1568009616666151106120434


Targeting Tumors with Small Molecule Peptides

, 2016; 16(6): 489-508.

Andrew G. Cheetham, Daniel Keith, Pengcheng Zhang, Ran Lin, Hao Su and Honggang Cui


DOI: 10.2174/1568009616666151130214646


Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy

, 2016; 16(2): 136-146.

Nobumichi Ohoka, Norihito Shibata, Takayuki Hattori and Mikihiko Naito


DOI: 10.2174/1568009616666151112122502


Regulation of Epithelial-Mesenchymal Transition by E3 Ubiquitin Ligases and Deubiquitinase in Cancer

, 2016; 16(2): 110-118.

Yasumichi Inoue, Yuka Itoh, Koichi Sato, Fumihiro Kawasaki, Chihiro Sumita, Takahito Tanaka, Daisuke Morishita and Hidetoshi Hayashi


DOI: 10.2174/1568009616666151112122126


S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway

, 2016; 16(5): 455-465.

Zongliang Lu, Rui Zhou, Ya Kong, Jiajia Wang, Wanyuan Xia, Jing Guo, Jie Liu, Hailan Sun, Kai Liu, Jian Yang, Mantian Mi and Hongxia Xu


DOI: 10.2174/1568009616666151207105720



CD20-based Immunotherapy of B-cell Derived Hematologic Malignancies

, 2017; 17(5): 423-444.

Dariush Shanehbandi, Jafar Majidi*, Tohid Kazemi*, Behzad Baradaran and Leili Aghebati-Maleki


DOI: 10.2174/1568009617666170109151128





Targeting Signaling Pathways in Chronic Lymphocytic Leukemia

, 2016; 16(8): 669-688.

Alice F. Muggen, Simar P. Singh, Rudi W. Hendriks and Anton W. Langerak


DOI: 10.2174/1568009616666160408145623



Most Accessed Articles



Paclitaxel Resistance: Molecular Mechanisms and Pharmacologic Manipulation

, 2003; 3(1): 1-19.

R. Z. Yusuf, Z. Duan, D. E. Lamendola, R. T. Penson and M. V. Seiden


DOI: 10.2174/1568009033333754


Tunneling Nanotubes: A Versatile Target for Cancer Therapy

, 2018; 18(6): 514-521.

Pragyaparamita Sahu, Soumya Ranjan Jena and Luna Samanta*


DOI: 10.2174/1568009618666171129222637




Immunomodulatory Drugs (IMiDs) in Multiple Myeloma

, 2017; 17(9): 846-857.

Shahzad Raza, Rachael A. Safyan and Suzanne Lentzsch*


DOI: 10.2174/1568009617666170214104426




The Urokinase Plasminogen Activator System: A Target for Anti-Cancer Therapy

, 2009; 9(1): 32-71.

Salvatore Ulisse, Enke Baldini, Salvatore Sorrenti and Massimino D'Armiento


DOI: 10.2174/156800909787314002



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