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Current Bioactive Compounds

Volume 15, 6 Issues, 2019
ISSN: 1875-6646 (Online)
ISSN: 1573-4072 (Print)
This journal supports open access

Aims & Scope

The journal aims to provide comprehensive review articles as well as research papers on new bioactive compounds with proven activities in various biological screenings and pharmacological models with a special emphasis on stereoeselective synthesis. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia.

The journal should prove to be essential reading for pharmacologists, natural product chemists and medicinal chemists who wish to be kept informed and up-to-date with the most important developments on new bioactive compounds of natural or synthetic origin, including their stereoeselective synthesis.

Current Bioactive Compounds

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Volume 15

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Number 1



Biography   Open Access



Preface   Open Access



Review Article



Review Article



Review Article



Review Article



Research Article



Research Article

Anticancer Activity of Aminoacid Linked Novel 4-Methylumbelliferone Derivatives

, 15(1): 51 - 62

Manish Sinha*, Baljeet Kaur, Amandeep Kaur, Shruti Kuletha, Karanveer Singh and Rohit Bhatia


DOI: 10.2174/1573407213666170210143503




Articles Ahead of Print

Synthesis and In silico Studies of N-acylhydrazone Derivatives as hnRNP K Ligands with Potential Anti-cancer Activity


Wanderson Costa Souza, Lucas Danilo Dias, Jaqueline Evangelista de Queiroz, Hérika Danielle Almeida Vidal, Vinícius Barreto da Silva, Andréia Machado Leopoldino, Carlos Henrique Tomich de Paula da Silva, Giuliana Muniz Vila Verde and Gilberto Lucio Benedito Aquino*


View Abstract



Synthesis and Antibacterial / Anticancer Activities of Compounds Containing Pyrazole Ring Linked to Piperazines


Kishore Kumar Valluri, Tejeswara Rao Allaka, IV Kasi Viswanath* and Nagaraju PVVS


View Abstract






3,6-dichloro-1,2,4,5-Tetrazine Assayed at High Doses in the Metastatic Breast Cancer Cell Line MDA-MB-231 Reduces Cell Numbers and Induces Apoptosis


Mohamed Abdelkarim*, Khaoula Ben Younes, Ines Limam, Refka Guermazi, Amel Ben Ammaar El Gaaied and Fatma Ben Aissa-Fennira


View Abstract



Quinazolin-4-One: A Varsatile Molecule


Rakesh Amrutkar*, Sunil Amrutkar and Mahendrasing Ranawat


View Abstract


Abstracts Ahead of Print


Hypoglycemic effect of Calendula arvensis flowers is mediated by digestive enzyme inhibition


Abdul-Malik Abudunia, Ilias Marmouzi*, Mourad Kharbach, Meryem El Jemli, Karima Sayah, Abdelhakim Bouyahya, Ali Al-kaf, Ali Alyahawi, M`Hammed Ansar, Abdelaziz Bouklouze, My El Abbes Faouzi and Azeddine Ibrahimi


View Abstract



Chemical compounds and antioxidant activity of Centaurea solstitialis ssp. schouwii (DC.) Q. et S. (Asteraceae)


Lamia Aliouche, Paul Mosset, Francisco León, Ignacio Brouard, Samir Benayache, Djamel Sarri and Fadila Benayache*


View Abstract



Ex-vivo and in-vivo evidences of anti-inflammatory activity of p-aminophenol and salicylates derivatives


André Felipe Vilvert, Marcus Vinícius P.S. Nascimento, Rosivaldo dos Santos Borges and Eduardo M. Dalmarco*


View Abstract




A Review of Phytochemical and Pharmacological Studies of Inula Species


Aparoop Das, Anshul Shakya, Surajit Kumar Ghosh, Udaya Pratap Singh and Hans Raj Bhat*


View Abstract



Editor's Choice



Synthesis, Characterization and Evaluation of 1,3-Bisindolyl-2-Propen-1- One Derivatives as Potent Anti-Breast Cancer Agents

, 2018; 14(3): 299 - 308

Pravin S. Bhale, Hemant V. Chavan*, Sakharam B. Dongare, Sadanand N. Shringare, Yoginath B. Mule, Praffula B. Choudhari and Babasaheb P. Bandgar*


DOI: 10.2174/1573407213666170428112855



Design and Synthesis of Benzimidazole-4-carboxamides as Potent Poly(ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors

, 2018; 14(2): 100 - 111

Kalam B. Reddy, Gangula M. Rao*, Baru V. Kumar*, Chinmayee Choudhury and Kombu S. Rajan


DOI: 10.2174/1573407213666170109154209



Natural Occurring β-Peptides: A Fascinating World of Bioactive Molecules

, 2018; 14(1): 3 - 8

Azzurra Stefanucci, Sengul Uysal, Ramazan Ceylan and Gokhan Zengin*


DOI: 10.2174/1573407213666170405124107



Neoflavonoids as Prospective Compounds Against Parasitic Neglected Tropical Infections and Human Immunodeficiency Virus

, 2017; 13(4): 276 - 291

Gláucio B. Saldanha, George L.S. Oliveira, José C.C.L. da Silva, Maria C.P. Oliveira, Ana P.S.C.L. da Silva* and Juceni P. de Lima David


DOI: 10.2174/1573407213666170104152315







Open Access Articles

Antiplasmodial Compounds from Leaves of Dodonaea angustifolia

, 2017; 13(3): 268 - 273

Yadessa Melaku, Tefera Worku, Yemane Tadesse, Yalemtsehay Mekonnen, Juergen Schmidt, Norbert Arnold and Ermias Dagne*




Protodioscin, Isolated from the Rhizome of Dioscorea tokoro Collected in Northern Japan is the Major Antiproliferative Compound to HL-60 Leukemic Cells

, 2017; 13(2): 170 - 174

Manami Oyama, Tetsuo Tokiwano, Satoru Kawaii, Yasunori Yoshida, Kouichi Mizuno, Keimei Oh and Yuko Yoshizawa*









Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts

, 2013; 9(4): 324 - 332

Ahmed Nageeb, Azza Al-Tawashi, Abdul-Hamid Mohammad Emwas, Zeyad Abdel-Halim Al-Talla and Nahla Al-Rifai





Most Cited Articles


Piperine: A Comprehensive Review of Pre-Clinical and Clinical Investigations

, 2015; 11(3): 156-169.

Gopichand Chinta, Safiulla B. Syed, Mohane S. Coumar and Latha Periyasamy


DOI: 10.2174/1573407211666150915214425





Biological Activities of Salvia santolinifolia Boiss. A Multifunctional Medicinal Plant

, 2016; 12(4): 297-305.

Mir Babak Bahadori, Hassan Valizadeh, Behvar Asghari, Leila Dinparast, Shahram Bahadori and Mahdi Moridi Farimani


DOI: 10.2174/1573407212666160426161112


The Chemical Composition of Essential Oil of Warionea saharae Benth & Coss.(Fam.Asteraceae) from Southern Algeria

, 2015; 11(2): 116-121.

Minouna Yakoubi, Nasser Belboukhari, Khaled Sekkoum, Abdelkrim Cheriti, Mohammed Bouchekara and Hassan Y. Aboul-Enein


DOI: 10.2174/1573407211666150605224634


Essential Oil Chemical Composition of Vitex agnus-castus L. from Southern-West Algeria and Its Antimicrobial Activity

, 2016; 12(1): 51-60.

Abdallah Habbab, Khaled Sekkoum, Nasser Belboukhari, Abdelkrim Cheriti and Hassan Y. Aboul-Enein


DOI: 10.2174/1573407212666160330152633


Optimization of the Microwave-Assisted Extraction of Azadirachta indica (Neem) Leaves Using NMR-based Metabolic Fingerprinting

, 2015; 11(3): 142-145.

Simone Carradori, Luisa Mannina, Federica De Cosmi, Tamara Beccarini, Daniela Secci and Anatoly P. Sobolev


DOI: 10.2174/1573407211666151002001919




Most Accessed Articles


Synthesis, Characterization and Antifungal Activity of N-Methyl Chitosan and Its Application on the Gauze

, 2018; 14(4): 347-356.

Mardiyah Kurniasih*, Ratna S. Dewi, Purwati Purwati, Dadan Hermawan and Hassan Y. Aboul-Enein*


DOI: 10.2174/1573407213666170420171005



Synthesis and Biological Evaluation of Pyrazole amides fused Combretastatin Derivatives as Anticancer Agents

, 2018; 14(4): 357-363.

Kulkarni Kalpana, Kakarla R. Kumar, Ala V. Babu, Sreelatha Vanjivaka, Jyothi Vantikommu and Sadanandam Palle*


DOI: 10.2174/1573407213666170405122545


Investigation on Alocasia fornicata (Kunth) Schott as a Novel Source of Bioactive Vegetable Oil

, 2018; 14(4): 381-386.

Kawl Thanzami, Bibhuti Kakoti, Lalduhsanga Pachuau*, Manuranjan Gohain and Hauzel Lalhlenmawia


DOI: 10.2174/1573407213666170703145007


Anti Cancer, Molecular Docking and Structure Activity Relationship Studies of Some Novel Synthetic Spiroindolo[3,2-b]Carbazoles as Predicted HER2 and BrK Kinase Inhibitors

, 2018; 14(2): 119-133.

Mardia T. El Sayed*, Andrey Voronkov, Ifedayo V. Ogungbe, Salwa M. El-Hallouty, Khadiga M. Ahmed, Berishvili Vladimir and Konstantin Balaki


DOI: 10.2174/1573407213666170213154357


2-((1H-1,2,3-triazol-1-yl)methyl)-3-phenylquinazolin-4(3H)-ones: Design, Synthesis and Evaluation as Anti-cancer Agents

, 2018; 14(3): 254-263.

Kamala K. Vasu*, Hemantkumar D. Ingawale, Sneha R. Sagar, Jayesh A. Sharma, Dhaivat H. Pandya and Milee Agarwal


DOI: 10.2174/1573407213666170329131557


Natural Occurring β-Peptides: A Fascinating World of Bioactive Molecules

, 2018; 14(1): 3-8.

Azzurra Stefanucci, Sengul Uysal, Ramazan Ceylan and Gokhan Zengin*


DOI: 10.2174/1573407213666170405124107





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