Contents

Current Alzheimer Research, Volume 5 - Number 2

Editorial [ Production and Fate of Amyloid Peptides: Recent Advances and Perspectives ]

, 5(2): 90 - 91

Frederic Checler


DOI: 10.2174/156720508783954794




Processing of Amyloid Precursor Protein and Amyloid Peptide Neurotoxicity

, 5(2): 92 - 99

Pierrot Nathalie and Octave Jean-Noel


DOI: 10.2174/156720508783954721




BACE1 Structure and Function in Health and Alzheimers Disease

, 5(2): 100 - 120

Sarah L. Cole and Roger Vassar


DOI: 10.2174/156720508783954758




Memapsin 2 (Beta-Secretase) Inhibitors: Drug Development

, 5(2): 121 - 131

Arun K. Ghosh, Nagaswamy Kumaragurubaran, Ling Hong, Gerald Koelsh and Jordan Tang


DOI: 10.2174/156720508783954730




Assembly, Maturation, and Trafficking of the γ-Secretase Complex in Alzheimers Disease

, 5(2): 132 - 146

Daniel R. Dries and Gang Yu


DOI: 10.2174/156720508783954695




The Catalytic Core of γ-Secretase: Presenilin Revisited

, 5(2): 147 - 157

Harald Steiner


DOI: 10.2174/156720508783954677




γ-Secretase Inhibition and Modulation for Alzheimers Disease

, 5(2): 158 - 164

Michael S. Wolfe


DOI: 10.2174/156720508783954767




η-Secretase: Reduction of Amyloid Precursor Protein η-Site Cleavage in Alzheimers Disease

, 5(2): 165 - 171

Fuyuki Kametani


DOI: 10.2174/156720508783954776




From Presenilinase to γ-Secretase, Cleave to Capacitate

, 5(2): 172 - 178

Weiming Xia


DOI: 10.2174/156720508783954712




A Closer Look at α-Secretase

, 5(2): 179 - 186

Rolf Postina


DOI: 10.2174/156720508783954668




Part-Time α-Secretases: The Functional Biology of ADAM 9, 10 and 17

, 5(2): 187 - 201

Miriam Deuss, Karina Reiss and Dieter Hartmann


DOI: 10.2174/156720508783954686




Regulation of βAPP and PrPc Cleavage by α-Secretase: Mechanistic and Therapeutic Perspectives

, 5(2): 202 - 211

Bruno Vincent, Moustapha Alfa Cisse, Claire Sunyach, Marie-Victoire Guillot-Sestier and Frederic Checler


DOI: 10.2174/156720508783954749




Amyloid-Degrading Enzymes as Therapeutic Targets in Alzheimers Disease

, 5(2): 212 - 224

Natalia N. Nalivaeva, Lilia R. Fisk, Nikolai D. Belyaev and Anthony J. Turner


DOI: 10.2174/156720508783954785




Neprilysin and Amyloid Beta Peptide Degradation

, 5(2): 225 - 231

Louis B. Hersh and David W. Rodgers


DOI: 10.2174/156720508783954703




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