Contents

Current Alzheimer Research, Volume 4 - Number 5

Editorial [ Drug Discovery for Alzheimers Disease: Filling the Pipeline Guest Editors: Antony R. Horton and Howard M. Fillit ]

, 4(5): 501 - 502

Antony R. Horton and Howard M. Fillit


DOI: 10.2174/156720507783018172




Small Molecule Neurotrophin Receptor Ligands: Novel Strategies for Targeting Alzheimers Disease Mechanisms

, 4(5): 503 - 506

Frank M. Longo, Tao Yang, Juliet K. Knowles, Youmei Xie, Laura A. Moore and Stephen M. Massa


DOI: 10.2174/156720507783018316




NAP, A Neuroprotective Drug Candidate in Clinical Trials, Stimulates Microtubule Assembly in the Living Cell

, 4(5): 507 - 509

Illana Gozes and Inna Divinski


DOI: 10.2174/156720507783018208




Regeneration in a Degenerating Brain: Potential of Allopregnanolone as a Neuroregenerative Agent

, 4(5): 510 - 517

Jun Ming Wang, Ronald W. Irwin, Lifei Liu, Shuhua Chen and Roberta Diaz Brinton


DOI: 10.2174/156720507783018262




Oligomers of β-Amyloid Peptide Inhibit BDNF-Induced Arc Expression in Cultured Cortical Neurons

, 4(5): 518 - 521

Valentine Echeverria, Diego E. Berman and Ottavio Arancio


DOI: 10.2174/156720507783018190




Novel Multifunctional Anti-Alzheimer Drugs with Various CNS Neurotransmitter Targets and Neuroprotective Moieties

, 4(5): 522 - 536

Cornelis J. Van der Schyf, Silvia Mandel, Werner J. Geldenhuys, Tamar Amit, Yael Avramovich, Hailin Zheng, Mati Fridkin, Shunit Gal, Orly Weinreb, Orit Bar Am, Yotam Sagi and Moussa B.H. Youdim


DOI: 10.2174/156720507783018226




Detrimental Effects of Apolipoprotein E4: Potential Therapeutic Targets in Alzheimers Disease

, 4(5): 537 - 540

Robert W. Mahley, Yadong Huang and Karl H. Weisgraber


DOI: 10.2174/156720507783018334




APP-Based Neuroprotective Strategies

, 4(5): 541 - 543

Dale E. Bredesen and Shahrooz Rabizadeh


DOI: 10.2174/156720507783018253




Inhibition of Tau Aggregation in Cell Models of Tauopathy

, 4(5): 544 - 546

Inna Khlistunova, Marcus Pickhardt, Jacek Biernat, Yipeng Wang, Eva-Maria Mandelkow and Eckhard Mandelkow


DOI: 10.2174/156720507783018307




New Approaches to the Discovery of cdk5 Inhibitors

, 4(5): 547 - 549

Marcie A. Glicksman, Gregory D. Cuny, Min Liu, Brittany Dobson, Kenneth Auerbach, Ross L. Stein and Kenneth S. Kosik


DOI: 10.2174/156720507783018181




Perispinal Etanercept for Treatment of Alzheimers Disease

, 4(5): 550 - 552

Edward Tobinick


DOI: 10.2174/156720507783018217




Memory Improvement with Docosahexaenoic Acid Study (MIDAS)-Brief Review

, 4(5): 553 - 555

Karin Yurko-Mauro


DOI: 10.2174/156720507783018244




Is Alpha-Synuclein Pathology a Target for Treatment of Neurodegenerative Disorders?

, 4(5): 556 - 561

Manfred Windisch, Hans-Jorg Wolf, Birgit Hutter-Paier and Robert Wronski


DOI: 10.2174/156720507783018343




Discovery of ADDL-Targeting Small Molecule Drugs for Alzheimers Disease

, 4(5): 562 - 567

Gary C. Look, Jasna Jerecic, Diana B. Cherbavaz, Todd R. Pray, Jean-Claude R. Breach, Walter J. Crosier, Lev Igoudin, Catherine M. Hironaka, Raymond M. Lowe, Michele McEntee, Lily Ruslim-Litrus, Hsiu-Mei Wu, Sue Zhang, Susan M. Catalano, William F. Goure, David Summa and Grant A. Krafft


DOI: 10.2174/156720507783018271




Nogo Receptor Interacts with Brain APP and Aβ to Reduce Pathologic Changes in Alzheimers Transgenic Mice

, 4(5): 568 - 570

James H. Park and Stephen M. Strittmatter


DOI: 10.2174/156720507783018235




γ-Secretase Modulators

, 4(5): 571 - 573

Michael S. Wolfe


DOI: 10.2174/156720507783018299




A New Model for Academics Based Drug Discovery

, 4(5): 574 - 576

Ross L. Stein


DOI: 10.2174/156720507783018280




M1 Muscarinic Agonists Target Major Hallmarks of Alzheimers Disease – an Update

, 4(5): 577 - 580

Abraham Fisher


DOI: 10.2174/156720507783018163




Cytotoxicity of Aβ 1-42, RAGE23-54, and An Aβ -RAGE Complex in PC-12 Cells

, 4(5): 581 - 586

Shyamala Mruthinti, Nicholas Capito, Ajay Sood and Jerry J. Buccafusco


DOI: 10.2174/156720507783018325




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