Contents

Current Alzheimer Research, Volume 3 - Number 5

Marking the Centennial of Alzheimers First Report of the Disease with a Perspective of Ongoing Research and Future Challenge

, 3(5): 409 - 410

Debomoy K. Lahiri and Frank M. LaFerla


DOI: 10.2174/156720506779025260




Alzheimers and Dementia in the Oldest-Old: A Century of Challenges

, 3(5): 411 - 419

Claudia H. Kawas and Maria M. Corrada


DOI: 10.2174/156720506779025233




Filling the Gaps in the Aβ Cascade Hypothesis of Alzheimers Disease

, 3(5): 421 - 430

Todd E. Golde, Dennis Dickson and Michael Hutton


DOI: 10.2174/156720506779025189




Proteolytic Degradation of the Amyloid β-Protein: The Forgotten Side of Alzheimers Disease

, 3(5): 431 - 435

Malcolm A. Leissring


DOI: 10.2174/156720506779025206




Pathways by Which Aβ Facilitates Tau Pathology

, 3(5): 437 - 448

Mathew Blurton-Jones and Frank M. LaFerla


DOI: 10.2174/156720506779025242




The Role of Tau Phosphorylation in the Pathogenesis of Alzheimers Disease

, 3(5): 449 - 463

Kaihong Mi and Gail V.W. Johnson


DOI: 10.2174/156720506779025279




Genetic and Environmental Modifiers of Alzheimers Disease Phenotypes in the Mouse

, 3(5): 465 - 473

Davis Ryman and Bruce T. Lamb


DOI: 10.2174/156720506779025198




Taking Down the Unindicted Co-Conspirators of Amyloid β-Peptidemediated Neuronal Death: Shared Gene Regulation of BACE1 and APP Genes Interacting with CREB, Fe65 and YY1 Transcription Factors

, 3(5): 475 - 483

Debomoy K. Lahiri, Yuan-Wen Ge, Jack T. Rogers, Kumar Sambamurti, Nigel H. Greig and Bryan Maloney


DOI: 10.2174/156720506779025224




Progranulin Mutations in Ubiquitin-Positive Frontotemporal Dementia Linked to Chromosome 17q21

, 3(5): 485 - 491

Marc Cruts, Samir Kumar-Singh and Christine Van Broeckhoven


DOI: 10.2174/156720506779025251




Computer Simulations of Alzheimers Amyloid β-Protein Folding and Assembly

, 3(5): 493 - 504

Brigita Urbanc, Luis Cruz, David B. Teplow and H. Eugene Stanley


DOI: 10.2174/156720506779025170




A Role for TGF-β Signaling in Neurodegeneration: Evidence from Genetically Engineered Models

, 3(5): 505 - 513

Ina Tesseur and Tony Wyss-Coray


DOI: 10.2174/156720506779025297




Mitochondrial Dysfunction and Alzheimers Disease

, 3(5): 515 - 520

Xi Chen, David Stern and Shi Du Yan


DOI: 10.2174/156720506779025215




Beta-Amyloid, Oxidative Stress and Down Syndrome

, 3(5): 521 - 528

Ira T. Lott, Elizabeth Head, Eric Doran and Jorge Busciglio


DOI: 10.2174/156720506779025305




Imaging the Earliest Stages of Alzheimers Disease

, 3(5): 529 - 539

William Wu and Scott A. Small


DOI: 10.2174/156720506779025161




The Path from Anti Parkinson Drug Selegiline and Rasagiline to Multifunctional Neuroprotective Anti Alzheimer Drugs Ladostigil and M30

, 3(5): 541 - 550

Moussa B.H. Youdim


DOI: 10.2174/156720506779025288




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