Open Access Articles

Transcriptional Remodeling in Primary Hippocampal Astrocytes from an Alzheimer’s Disease Mouse Model

, 2018; 15(11): 986 - 1004

F. Ruffinatti, L. Tapella, I. Gregnanin, A. Stevano, G. Chiorino, P.L. Canonico, C. Distasi, A.A. Genazzani* and D. Lim*




Impact of the Presence of Select Cardiovascular Risk Factors on Cognitive Changes among Dementia Subtypes

, 2018; 15(11): 1032 - 1044

Katherine E. Irimata*, Brittany N. Dugger and Jeffrey R. Wilson




Technological Solutions for Older People with Alzheimer’s Disease: Review

, 2018; 15(10): 975 - 983

Petra Maresova*, Signe Tomsone, Petre Lameski, Joana Madureira, Ana Mendes, Eftim Zdravevski, Ivan Chorbev, Vladimir Trajkovik, Moriah Ellen and Kasper Rodile




Strategies for Continued Successful Treatment in Patients with Alzheimer’s Disease: An Overview of Switching Between Pharmacological Agents

, 2018; 15(10): 964 - 974

Rafael Blesa, Kazuhiro Toriyama*, Kengo Ueda, Sean Knox and George Grossberg




Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer’s Disease

, 2018; 15(10): 938 - 950

Martina Zverova, Eva Kitzlerova, Zdenek Fisar*, Roman Jirak, Jana Hroudova, Hana Benakova, Petra Lelkova, Pavel Martasek and Jiri Raboch




Short-Term Response to Cholinesterase Inhibitors in Alzheimer’s Disease Delays Time to Nursing Home Placement

, 2018; 15(10): 905 - 916

Carina Wattmo*, Elisabet Londos and Lennart Minthon





An Inflammation-related Nutrient Pattern is Associated with Both Brain and Cognitive Measures in a Multiethnic Elderly Population

, 2018; 15(5): 493 - 501

Yian Gu*, Jennifer J. Manly, Richard P. Mayeux and Adam M. Brickman




Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

, 2018; 15(5): 482 - 492

Kiyomi Nishimaki, Takashi Asada*, Ikuroh Ohsawa, Etsuko Nakajima, Chiaki Ikejima, Takashi Yokota, Naomi Kamimura and Shigeo Ohta*




Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers

, 2018; 15(2): 164 - 181

Roni Manyevitch, Matthew Protas, Sean Scarpiello, Marisa Deliso, Brittany Bass, Anthony Nanajian, Matthew Chang, Stefani M. Thompson, Neil Khoury, Rachel Gonnella, Margit Trotz, D. Blaine Moore, Emily Harms, George Perry, Lucy Clunes, Angelica Ortiz, Jan O. Friedrich and Ian V.J. Murray*




A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech

, 2018; 15(2): 130 - 138

Laszlo Toth*, Ildiko Hoffmann, Gabor Gosztolya, Veronika Vincze, Greta Szatloczki, Zoltan Banreti, Magdolna Pakaski and Janos Kalman




Biomarkers for Alzheimer's Disease Diagnosis

, 2017; 14(11): 1149 - 1154

Vasileios Mantzavinos and Athanasios Alexiou*





Association between Periodontal Health Status and Cognitive Abilitie s. The Role of Cytokine Profile and Systemic Inflammation

, 2017; 14(9): 978 - 990

Marta Sochocka*, Maciej Sobczyński , Aleksandra Sender-Janeczek , Katarzyna Zwolińska , Olga Błachowicz , Tomasz Tomczyk, Marek Ziętek and Jerzy Leszek





Impact of Cytokines and Chemokines on Alzheimer’s Disease Neuropathological Hallmarks

, 2017; 14(8): 870 - 882

Catarina Domingues, Odete A.B. da Cruz e Silva and Ana Gabriela Henriques*





Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer’s Disease

, 2017; 14(7): 696 - 708

Michael Hull*, Carl Sadowsky, Heii Arai, Ghislaine Le Prince Leterme, Ann Holstein, Kevin Booth, Yahong Peng, Tamotsu Yoshiyama, Hideo Suzuki, Nzeera Ketter, Enchi Liu and J. Michael Ryan





Comparison of Extracellular and Intracellular Blood Compartments Highlights Redox Alterations in Alzheimer's and Mild Cognitive Impairment Patients

, 2017; 14(1): 112 - 122

Noemí Arce-Varas, Giulia Abate, Chiara Prandelli, Carmen Martínez, Fernando Cuetos, Manuel Menéndez, Mariagrazia Marziano, David Cabrera-García, María Teresa Fernández-Sánchez, Antonello Novelli, Maurizio Memo and Daniela Uberti




Genetically-mediated Grey and White Matter Alteration in Normal Elderly Individuals with the CLU-C Allele Gene

, 2016; 13(11): 1302 - 1310

Lihua Qiu, Yong He, Hehan Tang, Yi Zhou, Jinhong Wang, Weiwei Zhang, Guangxiang Chen, Fei Zhao, Tingxue Ouyang, Bin Ju, Zhengyan Li, Lanlan Wang, Ling Zou and Qiyong Gong




Neuropsychiatric Disturbances in Alzheimer’s Disease: What Have We Learned from Neuropathological Studies?

, 2016; 13(10): 1145 - 1164

Debby Van Dam, Yannick Vermeiren, Alain D. Dekker, Petrus J.W. Naudé and Peter P. De Deyn




The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer’s Disease

, 2016; 13(9): 985 - 995

Marco Magistri, Dmitry Velmeshev, Madina Makhmutova, Prutha Patel, Gregory C. Sartor, Claude-Henry Volmar, Claes Wahlestedt and Mohammad Ali Faghihi




Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer’s Disease

, 2016; 13(9): 1040 - 1047

Wei Lu, Shu Yang, Lei Zhang, Lin Chen, Feng-Lei Chao, Yan-min Luo, Qian Xiao, Heng-Wei Gu, Rong Jiang and Yong Tang





Probabilistic Cost-Effectiveness Analysis of Vaccination for Mild or Moderate Alzheimer’s Disease

, 2016; 13(7): 809 - 816

Kuen-Cheh Yang and Hsiu-Hsi Chen





Perspectives on the Tertiary Prevention Strategy for Alzheimer’s Disease

, 2016; 13(3): 307 - 316

Xian-Le Bu, Shu-Sheng Jiao, Yan Lian and Yan-Jiang Wang




Defining the earliest pathological changes of Alzheimer’s disease

, 2016; 13(3): 281 - 287

James C. Vickers, Stan Mitew, Adele Woodhouse, Carmen M. Fernandez-Martos, Mathew T. Kirkcaldie, Alison J. Canty, Graeme H. McCormack and Anna E. King




Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

, 2015; 12(9): 814 - 828

Marcus Pickhardt, Thomas Neumann, Daniel Schwizer, Kari Callaway, Michele Vendruscolo, Dale Schenk, Peter St. George-Hyslop, Eva M. Mandelkow, Christopher M. Dobson, Lisa McConlogue, Eckhard Mandelkow and Gergely Toth





Neurobiology of Alzheimer’s Disease: Integrated Molecular, Physiological, Anatomical, Biomarker, and Cognitive Dimensions

, 2015; 12(8): 712 - 722

Joel Raskin, Jeffrey Cummings, John Hardy, Kory Schuh and Robert A. Dean




Social Markers of Mild Cognitive Impairment: Proportion of Word Counts in Free Conversational Speech

, 2015; 12(6): 513 - 519

Hiroko H. Dodge, Nora Mattek, Mattie Gregor, Molly Bowman, Adriana Seelye, Oscar Ybarra, Meysam Asgari and Jeffrey A. Kaye




1950 MHz Electromagnetic Fields Ameliorate Aβ Pathology in Alzheimer’s Disease Mice

, 2015; 12(5): 481 - 492

Ye Ji Jeong, Ga-Young Kang, Jong Hwa Kwon, Hyung-Do Choi, Jeong-Ki Pack, Nam Kim, Yun-Sil Lee and Hae-June Lee





Genetic Markers in Biological Fluids for Aging-Related Major Neurocognitive Disorder

, 2015; 12(3): 200 - 209

S.A. Castro-Chavira, T. Fernández, H. Nicolini, S. Diaz-Cintra and R.A. Prado-Alcalá





Age-Dependent Biochemical Dysfunction in Skeletal Muscle of Triple- Transgenic Mouse Model of Alzheimer`s Disease

, 2015; 12(2): 100 - 115

Vera F. Monteiro-Cardoso, Marisa Castro, M.M. Oliveira, Paula I. Moreira, Francisco Peixoto and Romeu A. Videira





Association of Smoking and Alcohol Drinking with Dementia Risk Among Elderly Men in China

, 2014; 11(9): 899 - 907

Shiming Zhou, Rui Zhou, Tingting Zhong, Rui Li, Jun Tan and Huadong Zhou





An Evaluation of MSDC-0160, A Prototype mTOT Modulating Insulin Sensitizer, in Patients with Mild Alzheimer's Disease

, 2014; 11(6): 564 - 573

Raj C. Shah, Dawn C. Matthews, Randolph D. Andrews, Ana W. Capuano, Debra A. Fleischman, James T. VanderLugt and Jerry R. Colca




Does an Interdisciplinary Network Improve Dementia Care? Results from the IDemUck-Study

, 2014; 11(6): 538 - 548

Leonore Kohler, Claudia Meinke-Franze, Jurgen Hein, Konstanze Fendrich, Romy Heymann, Jochen Rene Thyrian and Wolfgang Hoffmann




Biomarkers of Alzheimer's Disease Risk in Peripheral Tissues; Focus on Buccal Cells

, 2014; 11(6): 519 - 531

Maxime Francois, Wayne Leifert, Ralph Martins, Philip Thomas and Michael Fenech




Early Detection of Cerebral Glucose Uptake Changes in the 5XFAD Mouse

, 2014; 11(5): 450 - 460

I.R. Macdonald, D.R. DeBay, G.A. Reid, T.P. O’Leary, C.T. Jollymore, G. Mawko, S. Burrell, E. Martin, C.V. Bowen, R.E. Brown and S. Darvesh




Advances in High-Field Magnetic Resonance Spectroscopy in Alzheimer’s Disease

, 2014; 11(4): 367 - 388

Ningnannan Zhang, Xiaowei Song, Robert Bartha, Steven Beyea, Ryan D’Arcy, Yunting Zhang and Kenneth Rockwood





The prediction of response to Galantamine treatment in Patients with mild to moderate Alzheimer’s Disease

, 2014; 11(2): 110 - 118

Takashi Ohnishi, Yojiro Sakiyama, Yuichi Okuri, Yuji Kimura, Nami Sugiyama, Takayuki Saito, Masayoshi Takahashi and Takumi Kobayashi




Optimized Turmeric Extract Reduces β-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer’s Transgenic Mice

, 2012; 9(4): 500 - 506

R. Douglas Shytle, Jun Tan, Paula C. Bickford, Kavon Rezai-zadeh, L Hou, Jin Zeng, Paul R. Sanberg, Cyndy D. Sanberg, Randall S. Alberte, Ryan C. Fink and Bill Roschek Jr




Effects of Galantamine in Alzheimers Disease: Double-blind Withdrawal Studies Evaluating Sustained Versus Interrupted Treatment

, 2011; 8(7): 771 - 780

M. Gaudig, U. Richarz, J. Han, B. Van Baelen and B. Schauble




Frontotemporal Dementia Caused by CHMP2B Mutations

, 2011; 8(3): 246 - 251

A. M. Isaacs, P. Johannsen, I. Holm, J. E. Nielsen and FReJA Consortium




Long-Term Response to Galantamine in Relation to Short-Term Efficacy Data: Pooled Analysis in Patients with Mild to Moderate Alzheimers Disease

, 2011; 8(2): 175 - 186

S. Kavanagh, I. Howe, H. R. Brashear, D. Wang, B. Van Baelen, M. Todd and S. Schwalen




Baseline MRI Predictors of Conversion from MCI to Probable AD in the ADNI Cohort

, 2009; 6(4): 347 - 361

Shannon L. Risacher, Andrew J. Saykin, John D. Wes, Li Shen, Hiram A. Firpi and Brenna C. McDonald




Towards Retinoid Therapy for Alzheimers Disease

, 2009; 6(3): 302 - 311

K. Shudo, H. Fukasawa, M. Nakagomi and N. Yamagata





Long-Term Follow-Up of Patients Immunized with AN1792: Reduced Functional Decline in Antibody Responders

, 2009; 6(2): 144 - 151

Bruno Vellas, R. Black, Leon J. Thal, Nick C. Fox, M. Daniels, G. McLennan, C. Tompkins, C. Leibman, M. Pomfret and Michael Grundman





A New Glucocorticoid Hypothesis of Brain Aging: Implications for Alzheimers Disease

, 2007; 4(2): 205 - 212

Philip W. Landfield, Eric M. Blalock, Kuey-Chu Chen and Nada M. Porter





Induction of RhoGAP and Pathological Changes Characteristic of Alzheimers Disease by UAHFEMF Discharge in Rat Brain

, 2005; 2(5): 559 - 569

Ing-Feng Chang and Huo-Yen Hsiao





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