Open Access Articles ::: Current Alzheimer Research

ISSN: 1875-5828 (Online)
ISSN: 1567-2050 (Print)


Volume 14, 12 Issues, 2017


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Current Alzheimer Research

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Editor-in-Chief:
Prof. Debomoy K. Lahiri
Department of Psychiatry, Indiana University School of Medicine
Neuroscience Research Center
Indianapolis, IN 46202
USA


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Open Access Articles

Biomarkers for Alzheimer's Disease Diagnosis

, 2017; 14(11): 1149 - 1154

Vasileios Mantzavinos and Athanasios Alexiou*


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iTRAQ-based Proteomic Analysis of APPSw,Ind Mice Provides Insights into the Early Changes in Alzheimer’s Disease

, 2017; 14(10): 1109 - 1122

Nan Li, Pinghong Hu, Tiantian Xu, Huan Chen, Xiaoying Chen, Jianwen Hu, Xifei Yang, Lei Shi, Jian-hong Luo and Junyu Xu*


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Association between Periodontal Health Status and Cognitive Abilitie s. The Role of Cytokine Profile and Systemic Inflammation

, 2017; 14(9): 978 - 990

Marta Sochocka*, Maciej Sobczyński , Aleksandra Sender-Janeczek , Katarzyna Zwolińska , Olga Błachowicz , Tomasz Tomczyk, Marek Ziętek and Jerzy Leszek


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Impact of Cytokines and Chemokines on Alzheimer’s Disease Neuropathological Hallmarks

, 2017; 14(8): 870 - 882

Catarina Domingues, Odete A.B. da Cruz e Silva and Ana Gabriela Henriques*


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Abnormal Clock Gene Expression and Locomotor Activity Rhythms in Two Month-Old Female APPSwe/PS1dE9 Mice

, 2017; 14(8): 850 - 860

Olaide Oyegbami, Hilary M. Collins, Marie-Christine Pardon, Francis J.P. Ebling, David M. Heery and Paula M. Moran*


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Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer’s Disease

, 2017; 14(7): 696 - 708

Michael Hull*, Carl Sadowsky, Heii Arai, Ghislaine Le Prince Leterme, Ann Holstein, Kevin Booth, Yahong Peng, Tamotsu Yoshiyama, Hideo Suzuki, Nzeera Ketter, Enchi Liu and J. Michael Ryan


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Marginal Vitamin A Deficiency Exacerbates Memory Deficits Following Aβ1-42 Injection in Rats

, 2017; 14(5): 562 - 570

Jiaying Zeng, Tingyu Li, Ming Gong, Wei Jiang, Ting Yang, Jie Chen, Youxue Liu and Li Chen


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Comparison of Extracellular and Intracellular Blood Compartments Highlights Redox Alterations in Alzheimer's and Mild Cognitive Impairment Patients

, 2017; 14(1): 112 - 122

Noemí Arce-Varas, Giulia Abate, Chiara Prandelli, Carmen Martínez, Fernando Cuetos, Manuel Menéndez, Mariagrazia Marziano, David Cabrera-García, María Teresa Fernández-Sánchez, Antonello Novelli, Maurizio Memo and Daniela Uberti


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Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer’s Disease (AD): A Meta-Analysis of CSF Markers

, 2017; 14: 1 - 18 (E-Pub Ahead of Print)

Roni Manyevitch, Matthew Protas, Sean Scarpiello, Marisa Deliso, Brittany Bass, Anthony Nanajian, Matthew Chang, Stefani M. Thompson, Neil Khoury, Rachel Gonnella, Margit Trotz, D. Blaine Moore, Emily Harms, George Perry, Lucy Clunes, Angélica Ortiz, Jan O. Friedrich and Ian V.J. Murray*


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Genetically-mediated Grey and White Matter Alteration in Normal Elderly Individuals with the CLU-C Allele Gene

, 2016; 13(11): 1302 - 1310

Lihua Qiu, Yong He, Hehan Tang, Yi Zhou, Jinhong Wang, Weiwei Zhang, Guangxiang Chen, Fei Zhao, Tingxue Ouyang, Bin Ju, Zhengyan Li, Lanlan Wang, Ling Zou and Qiyong Gong


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Neuropsychiatric Disturbances in Alzheimer’s Disease: What Have We Learned from Neuropathological Studies?

, 2016; 13(10): 1145 - 1164

Debby Van Dam, Yannick Vermeiren, Alain D. Dekker, Petrus J.W. Naudé and Peter P. De Deyn


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The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer’s Disease

, 2016; 13(9): 985 - 995

Marco Magistri, Dmitry Velmeshev, Madina Makhmutova, Prutha Patel, Gregory C. Sartor, Claude-Henry Volmar, Claes Wahlestedt and Mohammad Ali Faghihi


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Decreased Myelinated Fibers in the Hippocampal Dentate Gyrus of the Tg2576 Mouse Model of Alzheimer’s Disease

, 2016; 13(9): 1040 - 1047

Wei Lu, Shu Yang, Lei Zhang, Lin Chen, Feng-Lei Chao, Yan-min Luo, Qian Xiao, Heng-Wei Gu, Rong Jiang and Yong Tang


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Misoprostol Reverse Hippocampal Neuron Cyclooxygenase-2 Downstream Signaling Imbalance in Aluminum-Overload Rats

, 2016; 13(9): 1006 - 1016

Yuanxin Guo, Wenjuan Lei, Jianfeng Wang, Xinyue Hu, Yuling Wei, Chaonan Ji and Junqing Yang


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Probabilistic Cost-Effectiveness Analysis of Vaccination for Mild or Moderate Alzheimer’s Disease

, 2016; 13(7): 809 - 816

Kuen-Cheh Yang and Hsiu-Hsi Chen


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Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model

, 2016; 13(6): 663 - 677

Jacob A. Irwin, Alev Erisir and Inchan Kwon


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Perspectives on the Tertiary Prevention Strategy for Alzheimer’s Disease

, 2016; 13(3): 307 - 316

Xian-Le Bu, Shu-Sheng Jiao, Yan Lian and Yan-Jiang Wang


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Defining the earliest pathological changes of Alzheimer’s disease

, 2016; 13(3): 281 - 287

James C. Vickers, Stan Mitew, Adele Woodhouse, Carmen M. Fernandez-Martos, Mathew T. Kirkcaldie, Alison J. Canty, Graeme H. McCormack and Anna E. King


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Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

, 2015; 12(9): 814 - 828

Marcus Pickhardt, Thomas Neumann, Daniel Schwizer, Kari Callaway, Michele Vendruscolo, Dale Schenk, Peter St. George-Hyslop, Eva M. Mandelkow, Christopher M. Dobson, Lisa McConlogue, Eckhard Mandelkow and Gergely Toth


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Increased Acetylation of Histone H4 at Lysine 12 (H4K12) in Monocytes of Transgenic Alzheimer’s Mice and in Human Patients

, 2015; 12(8): 752 - 760

Barbara Plagg, Daniela Ehrlich, Kathrin M. Kniewallner, Josef Marksteiner and Christian Humpel


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Neurobiology of Alzheimer’s Disease: Integrated Molecular, Physiological, Anatomical, Biomarker, and Cognitive Dimensions

, 2015; 12(8): 712 - 722

Joel Raskin, Jeffrey Cummings, John Hardy, Kory Schuh and Robert A. Dean


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Social Markers of Mild Cognitive Impairment: Proportion of Word Counts in Free Conversational Speech

, 2015; 12(6): 513 - 519

Hiroko H. Dodge, Nora Mattek, Mattie Gregor, Molly Bowman, Adriana Seelye, Oscar Ybarra, Meysam Asgari and Jeffrey A. Kaye


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1950 MHz Electromagnetic Fields Ameliorate Aβ Pathology in Alzheimer’s Disease Mice

, 2015; 12(5): 481 - 492

Ye Ji Jeong, Ga-Young Kang, Jong Hwa Kwon, Hyung-Do Choi, Jeong-Ki Pack, Nam Kim, Yun-Sil Lee and Hae-June Lee


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Oxidant/Antioxidant Imbalance and the Risk of Alzheimer's Disease

, 2015; 12(4): 335 - 349

Ahmed E. Abdel Moneim


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Genetic Markers in Biological Fluids for Aging-Related Major Neurocognitive Disorder

, 2015; 12(3): 200 - 209

S.A. Castro-Chavira, T. Fernández, H. Nicolini, S. Diaz-Cintra and R.A. Prado-Alcalá


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Role of Environmental Contaminants in the Etiology of Alzheimer’s Disease: A Review

, 2015; 12(2): 116 - 146

Manivannan Yegambaram, Bhagyashree Manivannan, Thomas G. Beach and Rolf U. Halden


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Age-Dependent Biochemical Dysfunction in Skeletal Muscle of Triple- Transgenic Mouse Model of Alzheimer`s Disease

, 2015; 12(2): 100 - 115

Vera F. Monteiro-Cardoso, Marisa Castro, M.M. Oliveira, Paula I. Moreira, Francisco Peixoto and Romeu A. Videira


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Caspase-3 Short Hairpin RNAs: A Potential Therapeutic Agent in Neurodegeneration of Aluminum-Exposed Animal Model

, 2014; 11(10): 961 - 970

Qinli Zhang, Na Li, Xia Jiao, Xiujun Qin, Ramanjit Kaur, Xiaoting Lu, Jing Song, Linping Wang, Junming Wang and Qiao Niu


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Association of Smoking and Alcohol Drinking with Dementia Risk Among Elderly Men in China

, 2014; 11(9): 899 - 907

Shiming Zhou, Rui Zhou, Tingting Zhong, Rui Li, Jun Tan and Huadong Zhou


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Severe Psychiatric Disorders in Mid-Life and Risk of Dementia in Late- Life (Age 65-84 Years): A Population Based Case-Control Study

, 2014; 11(7): 681 - 693

Renate R. Zilkens, David G. Bruce, Janine Duke, Katrina Spilsbury and James B. Semmens


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An Evaluation of MSDC-0160, A Prototype mTOT Modulating Insulin Sensitizer, in Patients with Mild Alzheimer's Disease

, 2014; 11(6): 564 - 573

Raj C. Shah, Dawn C. Matthews, Randolph D. Andrews, Ana W. Capuano, Debra A. Fleischman, James T. VanderLugt and Jerry R. Colca


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Does an Interdisciplinary Network Improve Dementia Care? Results from the IDemUck-Study

, 2014; 11(6): 538 - 548

Leonore Kohler, Claudia Meinke-Franze, Jurgen Hein, Konstanze Fendrich, Romy Heymann, Jochen Rene Thyrian and Wolfgang Hoffmann


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Biomarkers of Alzheimer's Disease Risk in Peripheral Tissues; Focus on Buccal Cells

, 2014; 11(6): 519 - 531

Maxime Francois, Wayne Leifert, Ralph Martins, Philip Thomas and Michael Fenech


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Early Detection of Cerebral Glucose Uptake Changes in the 5XFAD Mouse

, 2014; 11(5): 450 - 460

I.R. Macdonald, D.R. DeBay, G.A. Reid, T.P. O’Leary, C.T. Jollymore, G. Mawko, S. Burrell, E. Martin, C.V. Bowen, R.E. Brown and S. Darvesh


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Advances in High-Field Magnetic Resonance Spectroscopy in Alzheimer’s Disease

, 2014; 11(4): 367 - 388

Ningnannan Zhang, Xiaowei Song, Robert Bartha, Steven Beyea, Ryan D’Arcy, Yunting Zhang and Kenneth Rockwood


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Understanding the Complexities of Functional Ability in Alzheimer’s Disease: More Than Just Basic and Instrumental Factors

, 2014; 11(4): 357 - 366

Kristin Kahle-Wrobleski, Nicola Coley, Benoit Lepage, Christelle Cantet, Bruno Vellas, Sandrine Andrieu and PLASA/DSA Group


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The prediction of response to Galantamine treatment in Patients with mild to moderate Alzheimer’s Disease

, 2014; 11(2): 110 - 118

Takashi Ohnishi, Yojiro Sakiyama, Yuichi Okuri, Yuji Kimura, Nami Sugiyama, Takayuki Saito, Masayoshi Takahashi and Takumi Kobayashi


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Optimized Turmeric Extract Reduces β-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer’s Transgenic Mice

, 2012; 9(4): 500 - 506

R. Douglas Shytle, Jun Tan, Paula C. Bickford, Kavon Rezai-zadeh, L Hou, Jin Zeng, Paul R. Sanberg, Cyndy D. Sanberg, Randall S. Alberte, Ryan C. Fink and Bill Roschek Jr


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Effects of Galantamine in Alzheimers Disease: Double-blind Withdrawal Studies Evaluating Sustained Versus Interrupted Treatment

, 2011; 8(7): 771 - 780

M. Gaudig, U. Richarz, J. Han, B. Van Baelen and B. Schauble


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Frontotemporal Dementia Caused by CHMP2B Mutations

, 2011; 8(3): 246 - 251

A. M. Isaacs, P. Johannsen, I. Holm, J. E. Nielsen and FReJA Consortium


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Long-Term Response to Galantamine in Relation to Short-Term Efficacy Data: Pooled Analysis in Patients with Mild to Moderate Alzheimers Disease

, 2011; 8(2): 175 - 186

S. Kavanagh, I. Howe, H. R. Brashear, D. Wang, B. Van Baelen, M. Todd and S. Schwalen


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Baseline MRI Predictors of Conversion from MCI to Probable AD in the ADNI Cohort

, 2009; 6(4): 347 - 361

Shannon L. Risacher, Andrew J. Saykin, John D. Wes, Li Shen, Hiram A. Firpi and Brenna C. McDonald


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Towards Retinoid Therapy for Alzheimers Disease

, 2009; 6(3): 302 - 311

K. Shudo, H. Fukasawa, M. Nakagomi and N. Yamagata


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Natural Non-Trasgenic Animal Models for Research in Alzheimers Disease

, 2009; 6(2): 171 - 178

Manuel Sarasa and Pedro Pesini


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Long-Term Follow-Up of Patients Immunized with AN1792: Reduced Functional Decline in Antibody Responders

, 2009; 6(2): 144 - 151

Bruno Vellas, R. Black, Leon J. Thal, Nick C. Fox, M. Daniels, G. McLennan, C. Tompkins, C. Leibman, M. Pomfret and Michael Grundman


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Assembly of the Asparagine- and Glutamine-Rich Yeast Prions into Protein Fibrils

, 2008; 5(3): 251 - 259

Luc Bousset, Jimmy Savistchenko and Ronald Melki


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A New Glucocorticoid Hypothesis of Brain Aging: Implications for Alzheimers Disease

, 2007; 4(2): 205 - 212

Philip W. Landfield, Eric M. Blalock, Kuey-Chu Chen and Nada M. Porter


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De Novo and Molecular Target-Independent Discovery of Orally Bioavailable Lead Compounds for Neurological Disorders

, 2006; 3(3): 205 - 214

Laura K. Wing, Heather A. Behanna, Linda J. Van Eldik, D. Martin Watterson and Hantamalala Ralay Ranaivo


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Induction of RhoGAP and Pathological Changes Characteristic of Alzheimers Disease by UAHFEMF Discharge in Rat Brain

, 2005; 2(5): 559 - 569

Ing-Feng Chang and Huo-Yen Hsiao


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