Bentham Science Logo

Current Pharmaceutical Design

Volume 25, 46 Issues, 2019
ISSN: 1873-4286 (Online)
ISSN: 1381-6128 (Print)
This journal supports open access

Aims & Scope

Current Pharmaceutical Design publishes timely in-depth/mini reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.

Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.

Current Pharmaceutical Design

,

Volume 25

-

Number 8



Review Article

Modulation of CD44, EGFR and RAC Pathway Genes (WAVE Complex) in Epithelial Cancers

, 25(8): 833 - 848

Pranathi Tata, Piyush Gondaliya, Aditya Sunkaria, Akshay Srivastava and Kiran Kalia*


DOI: 10.2174/1381612825666190222143044


Review Article

Inhibition of Heat Shock Protein 90 as a Novel Platform for the Treatment of Cancer

, 25(8): 849 - 855

Chang Gao, Ya-Nan Peng, Hai-Zhou Wang, Shi-Lin Fang, Meng Zhang, Qiu Zhao and Jing Liu*


DOI: 10.2174/1381612825666190503145944


Review Article



Research Article

Evaluation of Local Injection of Bevacizumab against Triple-Negative Breast Cancer Xenograft Tumors

, 25(8): 862 - 870

Xin Jiang, Qiao-Li Zhang, Tie-Gang Liu, Wei-Peng Zhao, Ming Yang, Li-Na Wang, Wei-Liang Sun, Lin Pan, Ai-Ping Luo, Jin-Chang Huang* and Xiao-Hong Gu*


DOI: 10.2174/1381612825666190306164157


General Review Article

Ethnobotany, Phytochemistry and Traditional Uses of Curcuma spp. and Pharmacological Profile of Two Important Species (C. longa and C. zedoaria): A Review

, 25(8): 871 - 935

Zahra Ayati, Mahin Ramezani , Mohammad Sadegh Amiri, Ali Tafazoli Moghadam, Hoda Rahimi, Aref Abdollahzade, Amirhossein Sahebkar * and Seyed Ahmad Emami *


DOI: 10.2174/1381612825666190402163940


Current Pharmaceutical Design, Volume 25 (2019) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Recent Advances in Pharmaceutical Potential of Brown Algal Polysaccharides and their Derivatives


Jun Li, Chao Cai*, Chendong Yang, Jianghua Li, Tiantian Sun and Guangli Yu


View Abstract


Viewing the Emphasis on State-of-the-Art Magnetic Nanoparticles: Synthesis, Physical Properties, and Applications in Cancer Theranostics


Satyavani Kaliamurthi, Ayse Demir-Korkmaz, Gurudeeban Selvaraj, Emine Gokce-Polat, Yong-Kai Wei, Munirah Abdullah Almessiere, Abdulhadi Baykal, Keren Gu and Dong-Qing Wei*


View Abstract View on PubMed


Structure and Bioactivities of Porphyrans and Oligoporphyrans


Lihua Geng, Jing Wang, Zhongshan Zhang, Yang Yue and Quanbin Zhang*


View Abstract


Sulfated Polysaccharides from Macroalgae for Bone Tissue Regeneration


Jayachandran Venkatesan*, Sukumaran Anil, Sneha Rao, Se-Kwon Kim and Ira Bhatnagar


View Abstract


Alginate Nanoparticles for Drug Delivery and Targeting


Patr Severino, Classius F da Silva, Luciana N. Andrade, D. de Lima Oliveira, J. Campos and Eliana B. Souto*


View Abstract


Carrageenan: A Wonder Polymer from Marine Algae for Potential Drug Delivery Applications


Dilshad Qureshia, Suraj Kumar Nayaka, Samarandra Majib, Doman Kim, Indranil Banerjeea and Kunal Pala*


View Abstract


Molecular Mechanisms Underlying Cancer Preventive and Therapeutic Potential of Algal Polysaccharides


Soraya Sajadimajd, Saeideh Momtaz, Pouya Haratipour, Fardous F. El-Senduny, Amin Iran Panah, Jafar Navabi, Zhaleh Soheilikhah*, Mohammad Hosein Farzaei* and Roja Rahimi


View Abstract


Applications of Algal Polysaccharides and Derivatives in Therapeutic and Agricultural Fields


Bouissil S., Pierre G., El Alaoui-Talibi Z., Michaud P., El Modafar C. and Delattre C.*


View Abstract


Recent Advances in the Use of Algal Polysaccharides for Skin Wound Healing


Suneel Kumar, Ileana Marrero-Berrios, Maciej Kabat and Francois Berthiaume*


View Abstract View on PubMed



Abstracts Ahead of Print


Innovative Solutions for the Control of Leishmaniases: Nanoscale Drug Delivery Systems


Victoria Wagner, Aida Minguez-Menendez, Joan Pena and Christopher Fernandez-Prada*


View Abstract


Effects of As2O3 and resveratrol on the proliferation and apoptosis of colon cancer cells and the hERG-mediated potential mechanisms


Fengmei Li, Caichuan Yan, Yuhao Zhang, Yang Li, Mingzhu Li, Fang Wang, Guocui Zhang, Yuexin Li, Baoxin Li* and Xin Zhao


View Abstract




Navigating Research Toward the Re-emerging Nipah Virus- A New Piece to the Puzzle


Pritika Ramharack, Nikita Devnarain, Letitia Shunmugam and Mahmoud Soliman*


View Abstract


Nano-antimicrobials: A new paradigm for combating mycobacterial resistance


Prasad Minakshi*, Mayukh Ghosh, Basanti Brar, Rajesh Kumar, Upendra P Lambe, Koushlesh Ranjan, Gaya Prasad and Jinu Manoj


View Abstract


Lipid-Based Vectors for Therapeutic mRNA-Based Anti-Cancer Vaccines


Maria L Guevara, Stefano Persano* and Francesca Persano


View Abstract


The role of autophagy and death pathways in dose-dependent isoproterenol-induced cardiotoxicity


Alexandra Gyongyosi, Rita Zilinyi, Andras Czegledi, Agnes Tosaki, Arpad Tosaki and Istvan Lekli*


View Abstract



Published Contents

Editor's Choice


Molecular Basis of Modulating Adenosine Receptors Activities

, 2019; 25(7): 817 - 831

Mohammed Nooraldeen Mahmod Al-Qattan* and Mohd Nizam Mordi*


DOI: 10.2174/1381612825666190304122624



The Low Molecular Weight Brain-derived Neurotrophic Factor Mimetics with Antidepressant-like Activity

, 2019; 25(6): 729 - 737

Tatiana A. Gudasheva*, Polina Povarnina, Alexey V. Tarasiuk and Sergey B. Seredenin


DOI: 10.2174/1381612825666190329122852



Human Placental Vascular Reactivity in Health and Disease: Implications for the Treatment of Pre-eclampsia

, 2019; 25(5): 505 - 527

Emilie Hitzerd*, Michelle Broekhuizen, Rugina I. Neuman, Katrina M. Mirabito Colafella, Daphne Merkus, Sam Schoenmakers, Sinno H.P. Simons, Irwin K.M. Reiss and A.H. Jan Danser


DOI: 10.2174/1381612825666190405145228




Thrombolytic Therapy for Acute Ischemic Stroke: Past and Future

, 2019; 25(3): 242 - 250

Keita Shibata, Terumasa Hashimoto, Takuro Miyazaki*, Akira Miyazaki and Koji Nobe


DOI: 10.2174/1381612825666190319115018



Doxorubicin-induced Cardiotoxicity and Cardioprotective Agents: Classic and New Players in the Game

, 2019; 25(2): 109 - 118

Felipe dos Santos Arruda, Fernanda Dias Tomé, Marina Pacheco Miguel, Liliana Borges de Menezes, Patrícia Resende Alo Nagib, Erica Carolina Campos, Danilo Figueiredo Soave and Mara Rúbia Nunes Celes*


DOI: 10.2174/1381612825666190312110836



Interleukin-23 Blockers: Born to be First-line Biologic Agents in Inflammatory Bowel Disease?

, 2019; 25(1): 25 - 31

Marjorie C. Argollo, Mariangela Allocca, Federica Furfaro, Laurent Peyrin-Biroulet and Silvio Danese*


DOI: 10.2174/1381612825666190313140811





Open Access Articles



Small Molecules as PD-1/PD-L1 Pathway Modulators for Cancer Immunotherapy

, 2018; 24(41): 4911 - 4920

Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong and Bing Yan*





Novel Data on the Prevalence, Identification, Scouting, and Treatment of Familial Hypercholesterolaemia

, 2018; 24(31): 3597 - 3598

Michael Doumas, Konstantinos Imprialos, Konstantinos Stavropoulos and Vasilios G. Athyros





Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis

, 2018; 24(26): 3143 - 3151

Alexander N. Orekhov*, Yumiko Oishi , Nikita G. Nikiforov, Andrey V. Zhelankin, Larisa Dubrovsky, Igor A. Sobenin, Alexander Kel, Daria Stelmashenko, Vsevolod J. Makeev, Kathy Foxx, Xueting Jin, Howard S. Kruth and Michael Bukrinsky




Novel Technologies for Dipeptide Drugs Design and their Implantation

, 2018; 24(26): 3020 - 3027

Tatiana A. Gudasheva*, Rita U. Ostrovskaya and Sergey B. Seredenin




Coronary Microcirculation in Ischemic Heart Disease

, 2018; 24(25): 2893 - 2899

Axel R. Pries*, Wolfgang M. Kuebler and Helmut Habazettl




Next-generation Metabolomics in the Development of New Antidepressants: Using Albiflorin as an Example

, 2018; 24(22): 2530 - 2540

Jian Han, Yonghong Xia, Lejun Lin, Zuoguang Zhang, Hui Tian and Kefeng Li*





Defense Mechanisms Against Acid Exposure by Dental Enamel Formation, Saliva and Pancreatic Juice Production

, 2018; 24(18): 2012 - 2022

Robert Racz, Akos Nagy, Zoltan Rakonczay , Erika Katalin Dunavari, Gabor Gerber and Gabor Varga*




Peptide Mediated Brain Delivery of Nano- and Submicroparticles: A Synergistic Approach

, 2018; 24(13): 1366 - 1376

Mark McCully, Macarena Sanchez-Navarro , Meritxell Teixido* and Ernest Giralt*




Development of Peptide Vaccines in Dengue

, 2018; 24(11): 1157 - 1173

Kavita Reginald, Yanqi Chan, Magdalena Plebanski and Chit Laa Poh*






Most Cited Articles

Review Article

Polyphenols: Potential use in the prevention and treatment of cardiovascular diseases

, 1 January 2018; 24(2): 239-258.

Rosaria Vincenza Giglio, Angelo Maria Patti, Arrigo F.G. Cicero, Giuseppe Lippi, Manfredi Rizzo*, Peter P. Toth and Maciej Banach


DOI: 10.2174/1381612824666180130112652


Review Article

Curcumin: A natural pan-HDAC inhibitor in cancer

, 1 January 2018; 24(2): 123-129.

Sara Saffar Soflaei, Amir Abbas Momtazi-Borojeni, Muhammed Majeed, Giuseppe Derosa, Pamela Maffioli and Amirhossein Sahebkar*


DOI: 10.2174/1381612823666171114165051


Review Article

Colchicine pharmacokinetics and mechanism of action

, 2018; 24(6): 659-663.

Christos Angelidis*, Zoi Kotsialou, Charalampos Kossyvakis, Agathi-Rosa Vrettou, Achilleas Zacharoulis, Fotios Kolokathis, Vasilios Kekeris and Georgios Giannopoulos


DOI: 10.2174/1381612824666180123110042


Review Article

Recent findings in molecular basis of inflammation and anti-inflammatory plants

, 2018; 24(14): 1551-1562.

Sedigheh Kazemi, Hedayatollah Shirzad and Mahmoud Rafieian-Kopaei*


DOI: 10.2174/1381612824666180403122003


Review Article

Rapid-acting antidepressants

, 2018; 24(22): 2556-2563.

Jeffrey M. Witkin*, Daniel E. Knutson, Gabriel J. Rodriguez and Samuel Shi


DOI: 10.2174/1381612824666180730104707


Review Article

The role of formyl peptide receptors for immunomodulatory activities of antimicrobial peptides and peptidomimetics

, 2018; 24(10): 1100-1120.

Sarah Line Skovbakke*, Andre Holdfeldt, Huamei Forsman, Johan Bylund and Henrik Franzyk*


DOI: 10.2174/1381612824666180403123233


Review Article

Signaling pathways in inflammation and anti-inflammatory therapies

, 2018; 24(14): 1449-1484.

Yiu To Yeung, Faisal Aziz, Angelica Guerrero-Castilla and Sandro Arguelles*


DOI: 10.2174/1381612824666180327165604


Review Article

Curcumin as an adjunct therapy and microRNA modulator in breast cancer

, 1 January 2018; 24(2): 171-177.

Saeed Norouzi, Muhammed Majeed, Matteo Pirro, Daniele Generali and Amirhossein Sahebkar*


DOI: 10.2174/1381612824666171129203506


Research Article

PNitro-Tyr-PseAAC: Predict nitrotyrosine sites in proteins by incorporating five features into Chou’s general PseAAC

, 2018; 24(34): 4034-4043.

Ahmad W. Ghauri, Yaser D. Khan, Nouman Rasool, Sher A. Khan* and Kuo-Chen Chou


DOI: 10.2174/1381612825666181127101039


Research Article

Virtual screening and statistical analysis in the design of new caffeine analogues molecules with potential epithelial anticancer activity

, 2018; 24(5): 576-594.

Josivan da Silva Costa*, Karina da Silva Lopes Costa, Josiane Viana Cruz, Ryan da Silva Ramos, Luciane Barros Silva, Davi Do Socorro Barros Brasil, Carlos Henrique Tomich de Paula da Silva, Cleydson Breno Rodrigues dos Santos and Williams Jorge da Cruz Macedo


DOI: 10.2174/1381612823666170711112510


Review Article

Placental exosomes during gestation: Liquid biopsies carrying signals for the regulation of human parturition

, 2018; 24(9): 974-982.

Carlos Salomon*, Zarin Nuzhat, Christopher L. Dixon and Ramkumar Menon*


DOI: 10.2174/1381612824666180125164429


Review Article

Antibacterial coatings based on chitosan for pharmaceutical and biomedical applications

, 2018; 24(8): 866-885.

Juliana Miguel Vaz, Daniele Pezzoli, Pascale Chevallier, Clayton Souza Campelo, Gabriele Candiani and Diego Mantovani*


DOI: 10.2174/1381612824666180219143900


Review Article

Anti-cancer and radio-sensitizing effects of curcumin in nasopharyngeal carcinoma

, 2018; 24(19): 2121-2128.

Amir Abbas Momtazi-Borojeni, Faezeh Ghasemi, Amirreza Hesari, Muhammed Majeed, Michele Caraglia and Amirhossein Sahebkar*


DOI: 10.2174/1381612824666180522105202



Review Article

Potential use of nanomedicine for the anti-inflammatory treatment of neurodegenerative diseases

, 2018; 24(14): 1589-1616.

Maria Dolores Cayero-Otero, Ana M. Espinosa-Oliva*, Antonio J. Herrera, Irene Garcia-Dominguez, Mercedes Fernandez-Arevalo, Lucia Martin-Banderas and Rocio M. de Pablos


DOI: 10.2174/1381612824666180403113015



Most Accessed Articles

Advances in Binding Free Energies Calculations: QM/MM-Based Free Energy Perturbation Method for Drug Design

, 2013; 19(26): 4674-4686.

R.S. Rathore, M. Sumakanth, M. Siva Reddy, P. Reddanna, Allam Appa Rao, Mark D. Erion and M.R. Reddy


DOI: 10.2174/1381612811319260002


Reversal of Novel Anticoagulants in Emergent Surgery and Trauma: A Comprehensive Review and Proposed Management Algorithm

, 2018; 24(38): 4540-4553.

Leonidas Palaiodimos*, Jeremy Miles, Damianos G. Kokkinidis, Christos Barkolias, Anil K. Jonnalagadda, Dimitrios Papaconstantinou, Maximos Frountzas, Evangelos P. Misiakos and Dimitrios Schizas


DOI: 10.2174/1381612825666181226150629


Recent Advances in Cancer Therapy: An Overview

, 2010; 16(1): 3-10.

A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva, F. Vinals and G. Capella


DOI: 10.2174/138161210789941847



Computer-aided Drug Design and Drug Pharmacokinetic Prediction: A Mini-review

, 2018; 24(26): 3014-3019.

Jamshid Tabeshpour, Amirhossein Sahebkar*, Mohammad Reza Zirak, Majid Zeinali, Mahmoud Hashemzaei, Sajed Rakhshani and Saleh Rakhshani*


DOI: 10.2174/1381612824666180903123423


Association of SLCO1B1 Polymorphisms and Atorvastatin Safety and Efficacy: A Meta-analysis

, 2018; 24(34): 4044-4050.

Yaming Du, Sizheng Wang, Zhangyong Chen, Shusen Sun, Zhigang Zhao* and Xingang Li*


DOI: 10.2174/1381612825666181219163534



Rivaroxaban versus Clopidogrel for Peripheral Artery Disease: A Clinico-Economic Approach of the COMPASS Trial

, 2018; 24(38): 4516-4517.

Diamantis I. Tsilimigras, Demetrios Moris*, Georgios Karaolanis, Stavros K. Kakkos, Konstantinos Filis and Fragiska Sigala


DOI: 10.2174/1381612825666190101100832





Editor-in-Chief

William A. Banks
Seattle VA Puget Sound Health Care System
Room 810C, Building 1
1660 S. Columbian Way
Seattle, WA 98108
USA

Biography View Full Editorial Board

Journal History

Current Pharmaceutical Design was introduced in 1995 with the assistance of Dr. William A. Banks, who is the current Editor-in-Chief serving since 1995.
Track Your Manuscript:


Related Journals

Related eBooks

eBooks Catalog