Contents

Combinatorial Chemistry & High Throughput Screening, Volume 9 - Number 2

Editorial [ Efficient Medicinal Chemistry (Guest Editor: Donald J. Kyle)]

, 9(2): 77

Donald J. Kyle


DOI: 10.2174/138620706775541909




The Integration of Process R&D in Drug Discovery - Challenges and Opportunities

, 9(2): 79 - 86

Hans-Jurgen Federsel


DOI: 10.2174/138620706775541864




Achieving Maximum ROI from Corporate Databases: Exploiting Your Databases with Integrated Querying for Better Decision-Making

, 9(2): 87 - 93

L. F. Jardine, A. O. Krassavine, A. W.R. Payne and S. Porter


DOI: 10.2174/138620706775541837




Application and Utilization of Chemoinformatics Tools in Lead Generation and Optimization

, 9(2): 95 - 102

N. Fotouhi, P. Gillespie, R. A. Goodnow, S.- S. So, Y. Han and L. E. Babiss


DOI: 10.2174/138620706775541855




Improving Synthetic Efficiency Using the Computational Prediction of Biological Activity

, 9(2): 103 - 113

K. C. Brogle, T. Gund and D. J. Kyle


DOI: 10.2174/138620706775541846




Comparison of Methods for Sequential Screening of Large Compound Sets

, 9(2): 115 - 122

Paul E. Blower, Kevin P. Cross, Gabriel S. Eichler, Glenn J. Myatt, John N. Weinstein and Chihae Yang


DOI: 10.2174/138620706775541882




A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities

, 9(2): 123 - 130

X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie and D. Powers


DOI: 10.2174/138620706775541891




Interactive Tools for Risk Reduction and Efficiency Improvements in Medicinal Chemistry

, 9(2): 131 - 145

Kevin C. Brogle, Cindy Lin and Paul R. Blake


DOI: 10.2174/138620706775541828




Functional Characterisation of Homomeric Ionotropic Glutamate Receptors GluR1-GluR6 in a Fluorescence-Based High Throughput Screening Assay

, 9(2): 147 - 158

Mette Strange, Hans Brauner-Osborne and Anders A. Jensen


DOI: 10.2174/138620706775541918




Meet the Guest Editor

, 9(2): 159

Donald J. Kyle


DOI: 10.2174/138620706775541873




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