Contents

Combinatorial Chemistry & High Throughput Screening, Volume 8 - Number 6

Editorial

, 8(6): 457

Gilles H. Goetz


DOI: 10.2174/1386207054867319




Integrity Profiling of High Throughput Screening Hits Using LC-MS and Related Techniques

, 8(6): 459 - 466

Edward H. Kerns, Li Di, Jim Bourassa, Jonathan Gross, Nelson Huang, Hanlan Liu, Teresa Kleintop, Lisa Nogle, Larry Mallis, Chris Petucci, Susan Petusky, Mark Tischler, Chantel Sabus, Ani Sarkahian, Mairead Young, Mei-yi Zhang, Donna Huryn, Oliver McConnell and Guy Carter


DOI: 10.2174/1386207054867283




Interpretation of High-throughput Liquid Chromatography Mass Spectrometry Data for Quality Control Analysis and Analytical Method Development

, 8(6): 467 - 476

Bernard K. Choi, Michelle B. Ayer, Sal Siciliano, Jesus Martin, Robert Schwartz and James P. Springer


DOI: 10.2174/1386207054867300




Analytical and Biological Evaluation of High Throughput Screen Actives Using Evaporative Light Scattering, Chemiluminescent Nitrogen Detection, and Accurate Mass LC-MS-MS

, 8(6): 477 - 487

D.A. Peake, D.C. Duckworth, T.J. Perun, W.L. Scott, P. Kulanthaivel and M.A. Strege


DOI: 10.2174/1386207054867346




In situ DMSO Hydration Measurements of HTS Compound Libraries

, 8(6): 489 - 498

R. Ellson, R. Stearns, M. Mutz, C. Brown, B. Browning, D. Harris, S. Qureshi, J. Shieh and D. Wold


DOI: 10.2174/1386207054867382




High Throughput Sonication: Evaluation for Compound Solubilization

, 8(6): 499 - 512

Kevin Oldenburg, Douglas Pooler, Kurt Scudder, Christopher Lipinski and Michele Kelly


DOI: 10.2174/1386207054867364




The Novartis Compound Archive - From Concept to Reality

, 8(6): 513 - 519

U. Schopfer, C. Engeloch, J. Stanek, M. Girod, A. Schuffenhauer, E. Jacoby and P. Acklin


DOI: 10.2174/1386207054867328




HTS Quality Control and Data Analysis: A Process to Maximize Information from a High-Throughput Screen

, 8(6): 521 - 527

Ramesh Padmanabha, Lynda Cook and James Gill


DOI: 10.2174/1386207054867274




Chemical and Biological Integrity in Natural Products Screening

, 8(6): 529 - 534

George G. Harrigan and Gilles H. Goetz


DOI: 10.2174/1386207054867292




Meet The Guest Editor

, 8(6): 535

Gilles H. Goetz


DOI: 10.2174/1386207054867373




Improving Random Mutagenesis by Purification of the Oligonucleotide Variants

, 8(6): 537 - 544

P. Gaytan, J. Yanez, R. Grande, E. Morett and X. Soberon


DOI: 10.2174/1386207054867355




Efficient Construction of a Large Collection of Phage-Displayed Combinatorial Peptide Libraries

, 8(6): 545 - 551

Michael D. Scholle, John W. Kehoe and Brian K. Kay


DOI: 10.2174/1386207054867337




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