Contents

Combinatorial Chemistry & High Throughput Screening, Volume 8 - Number 4

Editorial [Hot Topic: Screening for Modulators of G Protein-Coupled Receptors (Guest Editor: Guido J.R. Zaman)]

, 8(4): 283

Guido J.R. Zaman


DOI: 10.2174/1386207054020750




G-Protein Coupled Receptor Assays: To Measure Affinity or Efficacy that is the Question

, 8(4): 285 - 292

C. Williams and A. Sewing


DOI: 10.2174/1386207054020778




The CellCard(™) System: A Novel Approach to Assessing Compound Selectivity for Lead Prioritization of G Protein-Coupled Receptors

, 8(4): 293 - 299

Oren Beske, Simon Goldbard and Pierre Turpin


DOI: 10.2174/1386207054020859




High Content Screening for G Protein-Coupled Receptors Using Cell-Based Protein Translocation Assays

, 8(4): 301 - 309

Charlotta Granas, Betina Kerstin Lundholt, Arne Heydorn, Viggo Linde, Hans-Christian Pedersen, Christian Krog-Jensen, Mette M. Rosenkilde and Len Pagliaro


DOI: 10.2174/1386207054020741




Functional G Protein-Coupled Receptor Assays for Primary and Secondary Screening

, 8(4): 311 - 318

Richard M. Eglen


DOI: 10.2174/1386207054020813




Using IMAP Technology to Identify Kinase Inhibitors: Comparison with a Substrate Depletion Approach and Analysis of the Nature of False Positives

, 8(4): 319 - 325

P. Singh, B. Lillywhite, C. Bannaghan and P. Broad


DOI: 10.2174/1386207054020769




Substrate Specificity and Novel Selective Inhibitors of TNF-α Converting Enzyme (TACE) from Two-Dimensional Substrate Mapping

, 8(4): 327 - 339

Millard H. Lambert, R. Kevin Blackburn, Theresa D. Seaton, Daniel B. Kassel, Daniel S. Kinder, M. Anthony Leesnitzer, D. Mark Bickett, Janet R. Warner, Marc W. Andersen, Jennifer G. Badiang, David J. Cowan, Michael D Gaul, Kimberly G. Petrov, Michael H. Rabinowitz, Robert W. Wiethe, J. David Becherer, Darryl L. McDougald, David L. Musso, Robert C. Andrews and Marcia L. Moss


DOI: 10.2174/1386207054020840




Rat PXR Reporter-Gene Activity Correlates with the Induction of CYP3A in Rat Precision-Cut Liver Slices

, 8(4): 341 - 346

Xiaoming Cui, Ann Thomas, Diana Montgomery, Chunyan Gu, Richard A. Morrison, Ronald E. White and K. -C. Cheng


DOI: 10.2174/1386207054020822




Identification of Nitric Oxide Donors by Biomimetic HTS Application

, 8(4): 347 - 352

Gyorgy T. Balogh, Balazs Dalmadi, Attila Bielik and Gyorgy M. Keseru


DOI: 10.2174/1386207054020831




High Throughput Coagulation Analyzers Review

, 8(4): 353 - 360

M. H. Qari


DOI: 10.2174/1386207054020796




Recent Advances in Analytical Construct Resins

, 8(4): 361 - 371

D. M. Whitehead, S. C. McKeown and A Routledge


DOI: 10.2174/1386207054020804




Meet the Guest Editor

, 8(4): 373

Guido J.R. Zaman


DOI: 10.2174/1386207054020787




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