Contents

Combinatorial Chemistry & High Throughput Screening, Volume 7 - Number 7

Preface [ Reverse Pharmacology and the Pharmaceutical Industry (Guest Editor: George G. Harrigan)]

, 7(7): ii

George G. Harrigan


DOI: 10.2174/13862073104070700ii




Quality, not Quantity: The Role of Natural Products and Chemical Proteomics in Modern Drug Discovery

, 7(7): 607 - 630

Andrew M. Piggott and Peter Karuso


DOI: 10.2174/1386207043328409




Current Progress in Natural Product-like Libraries for Discovery Screening

, 7(7): 631 - 643

Derek S. Tan


DOI: 10.2174/1386207043328418




Forward Chemical Genetics: Library Scaffold Design

, 7(7): 645 - 652

Sonya M. Khersonsky and Young-Tae Chang


DOI: 10.2174/1386207043328355




Synthetic Molecules that Modulate Transcription and Differentiation: Hints for Future Drug Discovery

, 7(7): 653 - 659

Motonari Uesugi


DOI: 10.2174/1386207043328373




Identification and Characterization of Sir2 Inhibitors Through Phenotypic Assays in Yeast

, 7(7): 661 - 668

Jeff Posakony, Maki Hirao and Antonio Bedalov


DOI: 10.2174/1386207043328346




Mapping Chemical Space Using Molecular Descriptors and Chemical Genetics: Deacetylase Inhibitors

, 7(7): 669 - 676

Stephen J. Haggarty, Paul A. Clemons, Jason C. Wong and Stuart L. Schreiber


DOI: 10.2174/1386207043328319




Target Identification Strategies in Chemical Genetics

, 7(7): 677 - 688

Gregory P. Tochtrop and Randall W. King


DOI: 10.2174/1386207043328391




Targeted Degradation of Proteins by Small Molecules: A Novel Tool for Functional Proteomics†

, 7(7): 689 - 697

D. Zhang, S.- H. Baek, A. Ho, H. Lee, Y. S. Jeong and K. Kim


DOI: 10.2174/1386207043328364




Photo-Affinity Labeling Strategies in Identifying the Protein Ligands of Bioactive Small Molecules: Examples of Targeted Synthesis of Drug Analog Photoprobes

, 7(7): 699 - 704

Jerry R. Colca and George G. Harrigan


DOI: 10.2174/1386207043328337




Meet the Guest Editor

, 7(7): 705

George G. Harrigan


DOI: 10.2174/1386207043328328




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