Open Access Articles

Protein Sequence Comparison and DNA-binding Protein Identification with Generalized PseAAC and Graphical Representation

, 2018; 21(2): 100 - 110

Chun Li*, Jialing Zhao, Changzhong Wang and Yuhua Yao




High Throughput Screening of Esterases, Lipases and Phospholipases in Mutant and Metagenomic Libraries: A Review

, 2016; 19(8): 605 - 615

Carlina Peña-García, Mónica Martínez-Martínez, Dolores Reyes-Duarte* and Manuel Ferrer*




An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever

, 2016; 19(7): 516 - 536

Chelsea N. Powers and William N. Setzer*




Identification of Protein Palmitoylation Inhibitors from a Scaffold Ranking Library

, 2016; 19(4): 262 - 274

Laura D. Hamel, Brian J. Lenhart, David A. Mitchell, Radleigh G. Santos, Marc A. Giulianotti and Robert J. Deschenes*




Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP

, 2015; 18(1): 3 - 17

Arjan J. van Adrichem, Annika Fagerholm, Laura Turunen, Anna Lehto, Jani Saarela, Ari Koskinen, Gretchen A. Repasky and Krister Wennerberg*




Digital Holographic Microscopy: A Quantitative Label-Free Microscopy Technique for Phenotypic Screening

, 2014; 17(1): 80 - 88

Benjamin Rappaz, Billy Breton, Etienne Shaffer and Gerardo Turcatti*




Chemical Informatics and the Drug Discovery Knowledge Pyramid

, 2013; 16(10): 764 - 776

Gerald H. Lushington*, Yinghua Dong and Bhargav Theertham




A Generalized Model and High Throughput Data Analysis System for Functional Modulation of Receptor-Agonist Systems Suitable for use in Drug Discovery

, 2013; 16(3): 199 - 209

Aaron C. Pawlyk*, R. Kyle Palmer, Dennis Sprous and Chip Allee




A Simple Method for Analyzing Actives in Random RNAi Screens: Introducing the “H Score” for Hit Nomination & Gene Prioritization

, 2012; 15(9): 686 - 704

Bhavneet Bhinder and Hakim Djaballah*




Application of NMR Metabolomics to Search for Human Disease Biomarkers

, 2012; 15(8): 595 - 610

Teklab Gebregiworgis and Robert Powers*




Alternative Medicine Safety: Agaricus blazei and Propolis

, 2011; 14(7): 616 - 621

Kenji Sorimachi* and Takaaki Nakamoto




The Design and Application of Target-Focused Compound Libraries

, 2011; 14(6): 521 - 531

C. John Harris, Richard D. Hill, David W. Sheppard*, Martin J. Slater and Pieter F.W. Stouten




Two Panels of Steroid Receptor Luciferase Reporter Cell Lines for Compound Profiling

, 2011; 14(4): 248 - 266

David Sedlak, Aileen Paguio and Petr Bartunek*




Building a Tiered Approach to In Vitro Predictive Toxicity Screening: A Focus on Assays with In Vivo Relevance

, 2010; 13(2): 188 - 206

James M. McKim Jr.*




Generating ‘Omic Knowledge’: The Role of Informatics in High Content Screening

, 2009; 12(9): 917 - 925

Mark A. Collins*




Applications of High Content Screening in Life Science Research

, 2009; 12(9): 870 - 876

Joseph M. Zock*




Combinatorics of Reaction-Network Posets

, 2008; 11(9): 723 - 733

Douglas J. Klein*, Teodora Ivanciuc, Anton Ryzhov and Ovidiu Ivanciuc




Machine Learning for In Silico Virtual Screening and Chemical Genomics: New Strategies

, 2008; 11(8): 677 - 685

Jean-Philippe Vert* and Laurent Jacob




Fluorescent Probes for Cellular Assays

, 2008; 11(7): 505 - 513

George T. Hanson and Bonnie J. Hanson*




Label-Free Cell-Based Assays for GPCR Screening

, 2008; 11(5): 357 - 369

Ye Fang*, Anthony G. Frutos and Ronald Verklereen




Pharmacological Characterization of Ligands at Recombinant NMDA Receptor Subtypes by Electrophysiological Recordings and Intracellular Calcium Measurements

, 2008; 11(4): 304 - 315

Kasper B. Hansen*, Hans Brauner-Osborne and Jan Egebjerg




Back to Basics: Label-Free Technologies for Small Molecule Screening

, 2008; 11(3): 231 - 237

Andrew K. Shiau*, Mark E. Massari and Can C. Ozbal




Discovery of Novel Targets with High Throughput RNA Interference Screening

, 2008; 11(3): 175 - 184

Paul D. Kassner*




High Throughput Screening of Gene Functions in Mammalian Cells Using Reversely Transfected Cell Arrays: Review And Protocol

, 2008; 11(2): 159 - 172

Michael Sturzl*, Andreas Konrad, Gaby Sander, Effi Wies, Frank Neipel, Elisabeth Naschberger, Simone Reipschlager, Nathalie Gonin-Laurent, Raymund E. Horch, Ulrich Kneser, Werner Hohenberger, Holger Erfle and Mathias Thurau




Yeast Genomics and Drug Target Identification

, 2007; 10(8): 618 - 634

Nike Bharucha and Anuj Kumar*




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