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Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 24, 10 Issues, 2021
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access

Articles Ahead of Print


Nutraceuticals for Sleep Disorders


Ruhi Ali*, Sana Tariq, Ozaifa Kareem, Faizana Fayaz, Tahira Aziz, Meenu Dinesh, Faheem Hyder Pottoo and Nadeem Siddiqui


DOI: 10.2174/1386207324666210121111446
View Abstract View on PubMed








Herbal Medicine: Clinical Perspective & Regulatory Status


Md Abul Barkat*, Anjali Goyal, Harshita Abul Barkat, Mohammad Salauddin, Faheem Hyder Pottoo and Esra T. Anwer


DOI: 10.2174/1386207323999201110192942
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Envisioning the Future of Nanomedicines in Management and Treatment of Neurological Disorders


Shobhit Kumar*, Priyanka Singh, Shrestha Sharma, Faheem Hyder Pottoo, Javed Ali and Sanjula Baboota


DOI: 10.2174/1386207323666201217151132
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On m-polar Diophantine Fuzzy N-soft set with Applications


Jia-Bao Liu, Shahbaz Ali*, Muhammad Khalid Mahmood and Muhammad Haris Mateen


DOI: 10.2174/1386207323666201230092354
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Molecular Mechanisms of Thymoquinone as Anticancer Agent


Fatma Alhmied, Ali Alammar, Bayan Alsultan, Muruj Alshehri and Faheem Hyder Pottoo*


DOI: 10.2174/1386207323999201027225305
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Phyto-chlorophyllin prevents food additive induced genotoxicity and mitochondrial dysfunction via cytochrome c mediated pathway in mice model


Asmita Samadder*, Sudatta Dey, Priyanka Sow, Ruchira Das, Sisir Nandi, Jayeeta Das*, Banani Bhattacharjee, Arnob Chakrovorty, Maharaj Biswas and Pradeepta Guptaroy


DOI: 10.2174/1386207323666201230093510
View Abstract









Anti-Cancer and Antibacterial Effects of Terfezia boudieri-Derived Silver Nanoparticles


Hashem Yaghoubi*, Amin Izadpanah*, Shahla Nedaei, Hossein Akbari, Elmira Mikaeili Agah, Ricardo Mostany, Bysani Chandrasekar, Eckhard Alt and Reza Izadpanah


DOI: 10.2174/1386207323999201117113401
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Ziziphus spina-christi Leaf Extract Mitigates Mercuric Chloride-induced Cortical Damage in Rats


Rafa S. Almeer*, Saad Alkahtani, Saud Alarifi, Ahmed E. Abdel Moneim, Saba Abdi and Gadah Albasher


DOI: 10.2174/1386207323666201204124412
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Identification of an MiRNA-mRNA Regulatory Network in Colorectal Cancer


Ming-fu Cui, Yuan-yu Wu, Ming-yan Chen, Yang Zhao, Song-yun Han, Rui-jie Wang, Haiyan Zhang and Xue-dong Fang*


DOI: 10.2174/1386207323666201110154142
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Virus as nanocarrier for drug delivery redefining medical therapeutics - A status report


Sanjay Kumar Ojha*, Ritesh Pattnaik, Puneet Kumar Singh, Shubha Dixit, Snehasish Mishra, Sreyasi Pal and Subrat Kumar*


DOI: 10.2174/1386207323666201218115850
View Abstract





Serum Pro-oxidant-Antioxidant Balance in subjects with Type 2 Diabetes Mellitus


Mahsa Ahmadnezhad, Hamideh Ghazizadeh, Moniba Bijari, Mohammad Reza Oladi, Habibollah Esmaily, Seyed Javad Hoseini, Elham Barati, Samaneh Silakhori, Maryam Moham-madi-Bajgiran, Hafezeh Davari, Mohammad Reza Parizadeh, Naghme Mokhber, Payam Sharifan, Seyed Rafie Aref- Hosseini, Gordon A Ferns, Mohsen Moohebati and Majid Ghayour-Mobarhan*


DOI: 10.2174/1386207323999201103203153
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Total Irregularity Strengths of an Arbitrary Disjoint Union of (3,6)- Fullerenes


Ayesha Shabbir, Muhammad Faisal Nadeem*, Mohammad Ovais, Faraha Ashraf and Sumiya Nasir


DOI: 10.2174/1386207323666201209094514
View Abstract





Exploring the mystery of osteoarthritis using bioinformatics analysis from cartilage tissue


Bin Wang, Jun-Long Zhong, Ning Jiang, Jie Shang, Biao Wu, Yu-Feng Chen and Hua-Ding Lu*


DOI: 10.2174/1386207323666201207100905
View Abstract





Neobavaisoflavone demonstrates valid antitumor effects in Non-Small-Cell Lung Cancer by inhibiting STAT3


Xueding Cai, Feng Zhou, Xiaona Xie, Dandan Zheng, Yulei Yao, Chengguang Zhao, Xiaoying Huang and Ke Hu*


DOI: 10.2174/1386207323666201204135941
View Abstract









Chitosan and Wnt/β-catenin Signaling Pathways in Different Cancers


Masoumeh Eslahi, Fatemeh Sadoughi, Zatollah Asemi, Bahman Yousefi, Mohammad Ali Mansournia and Jamal Hallajzadeh*


DOI: 10.2174/1386207323666201020105736
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The Pattern of Calculated Inflammation Ratios as Prognostic Values in Patients with Colorectal Cancer


Andra Ciocan, Sorana D. Bolboacă*, Cristina Drugan, Răzvan A. Ciocan, Florin Graur and Nadim AL Hajjar


DOI: 10.2174/1386207323666201020111946
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Exploring the Mechanism of Swertia mussotii Franch. for Hepatoprotective Effects with iTRAQ LC-MS/MS


Haixia Yun, Xinyu Wu, Yiwei Ding, Wendou Xiong, Xianglan Duan, Hui Gao, Yingzhong Yang and Zhi Chen*


DOI: 10.2174/1386207323666201020111301
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Mechanistic Insights to the Binding of Antibody CR3022 Against RBD from SARS-CoV and HCoV-19/SARS-CoV-2: A Computational Study


Wei Yu, Xiaomin Wu, Jiayi Ren, Xiaochun Zhang, Yueming Wang, Chengming Li, Wenwen Xu, Jason Li, Gang Li, Weihong Zheng, Huaxin Liao and Xiaohui Yuan*


DOI: 10.2174/1386207323666201026160500
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Metabolic Profile of Dendrobine in Rats Determined by Ultra-high-performance Liquid Chromatography/Quadrupole Time-of-flight Mass Spectrometry


Jun-qi Bai, Qian-xiang Guo, Jing Zhang, Juan Huang, Wen Xu, Lu Gong, He Su, Yu-bing Luo, Jian-hua Li, Xiao-hui Qiu and Zhi-hai Huang*


DOI: 10.2174/1386207323666201023115744
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Physical Analysis of Heat for Formation and Entropy of Ceria Oxide Using Topological Indices


Xiujun Zhang, Muhammad Kamran Siddiqui*, Sana Javed, Lubna Sherin, Farah Kausar and Mehwish Hussain Muhammad


DOI: 10.2174/1386207323999201001210832
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Synthesis, Characterization, Antitubercular and Anti-Inflammatory Activity of New Pyrazolo[3,4-d]Pyrimidines


Ravindra Kulkarni*, Krishna Kompalli, Naveen Gaddam, Chandrashekar V, Bikshupati Darna, Achaiah Garlapati, Dileep Kumar and Baswaraju Machha


DOI: 10.2174/1386207323999200918114905
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Acute Inflammation and Oxidative Stress Induced by Lipopolysaccharide and the Ameliorative Effect of Stingless Bee Honey


Yazan Ranneh*, Ayman M. Mahmoud*, Abdulmannan Fadel, Mohammed Albujja, Abdah Md Akim, Hasiah Ab. Hamid and Huzwah Khazaai


DOI: 10.2174/1386207323999200918152111
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Carbon Nano Tubes: Novel Drug Delivery System in Amelioration of Alzheimer’s Disease


Jayanti Mishra, Bhumika Kumar, Mukesh Pandey, Faheem Hyder Pottoo, Faizana Fayaz, Firdos Alam Khan and P.K. Sahoo*


DOI: 10.2174/1386207323999200918112538
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A 13-Immune Gene Set Signature for Prediction of Colon Cancer Prognosis


Zhuo Lu, Jin Chen, JiongYi Yan, QiaoMing Liu, Fang Li, WanNa Xiong, Shida Lin, Kai Yu and Jianqin Liang*


DOI: 10.2174/1386207323666200930104744
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Astaxanthin Prevents Lung Injury Due to Hyperoxia and Inflammation


Hasan Akduman*, Cüneyt Tayman, Ufuk Çakir, Esra Çakir, Dilek Dilli, Tuğba Taşkin Türkmenoğlu and Ataman Gönel


DOI: 10.2174/1386207323666200915092012
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Protective Effects of Astaxanthin on Nephrotoxicity in Rats with Induced Renovascular Occlusion


Erkan Arslan, Hakan Turk*, Murat Caglayan, Tugba Taskin Turkmenoglu, Ataman Gonel and Cuneyt Tayman


DOI: 10.2174/1386207323666200914104432
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Protective Role of Morus nigra Leaf Extracts Against Murine Infection with Eimeria papillata


Felwa A. Thagfan*, Wafa A. Al-Megrin, Esam M. Al-Shaebi, Saleh Al-Quraishy and Mohamed A. Dkhil


DOI: 10.2174/1386207323666200903152811
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Interpretable SMILES-based QSAR Model of Inhibitory Activity of Sirtuins 1 and 2


Apilak Worachartcheewan*, Alla P. Toropova, Andrey A. Toropov, Reny Pratiwi, Virapong Prachayasittikul and Chanin Nantasenamat


DOI: 10.2174/1386207323666200902141907
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Exploring the Mechanism of Lingzhu San in Treating Febrile Seizures by Using Network Pharmacology


Xiao Zhou, Xiao-Fei Zhang, Dong-Yan Guo, Yan-Jun Yang, Lin Liu, Lin Wang, Xue Zhang, Jiang-Xue Cheng, Jun-Bo Zou and Ya-Jun Shi*


DOI: 10.2174/1386207323666200902144348
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Osteopontin is a Prognostic Factor in Patients with Advanced Gastric Cancer


Ozan Yazici*, Mutlu Dogan, Guze Ozal, Sedef Hande Aktas, Ahmet Demirkazik, Gungor Utkan, Filiz Cay Senler, Fikri Icli and Hakan Akbulut


DOI: 10.2174/1386207323666200902135349
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A Potential MRI Agent and an Anticancer Drug Encapsulated within CPMV Virus-Like Particles


Alaa A A Aljabali*, Lorca Alzoubi, Yassmen Hamzat, Alaa Alqudah, Mohammad A. Obeid, Mazhar S. Al Zoubi, Raed M Ennab, Walhan Alshaer, Khaled Albatayneh, Bahaa Al‑Trad, Dana A. Alqudah, Dinesh Kumar Chellappan, Gaurav Gupta, Murtaza M. Tambuwala, Dua Kamal and David J Evans


DOI: 10.2174/1386207323666200914110012
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Lead Finding from Selected Flavonoids with Antiviral (SARS-CoV-2) Potentials Against COVID-19: An In-silico Evaluation


Uma Sankar Gorla*, GSN Koteswara Rao, Uma Sankar Kulandaivelu, Rajasekhar Reddy Alavala and Siva Prasad Panda


DOI: 10.2174/1386207323999200818162706
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DSARna: RNA Secondary Structure Alignment Based on Digital Sequence Representation


Longjian Gao, Chengzhen Xu*, Wangan Song, Feng Xiao, Xiaomin Wu, Li Shi, Yuxuan Sun and Jun Li


DOI: 10.2174/1386207323666200811100338
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Pollen Beads: A New Carrier for Propolis Active Compounds


Şaban Keskin*, Boryana Trusheva, Merve Keskin, Milena Popova, Sevgi Kolaylı and Vassya Bankova


DOI: 10.2174/1386207323666200720102651
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Editor-in-Chief

Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)
Biography
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Journal History

Combinatorial Chemistry & High Throughput Screening Journal was launched in 1998. Dr. Gerald H. Lushington serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 2.4

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