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Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 25, 14 Issues, 2022
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access

Articles Ahead of Print












Impact of MiRNAs and LncRNAs on Multidrug Resistance of Gastric Cancer


Yiwen Wu, Xiaoyan Yang*, Zhizhong Xie, Haihong Hu, Xiaoyong Lei, Dun Niu, Shiyan Li and Lu Tuo


DOI: 10.2174/1386207325666220401090604
View Abstract View on PubMed


In-silico Validation of the Proposed Treatment Strategy of Periodontitis


Pooja Jain, Uzma Farooq, Lalit Mohan Nainwal, Mumtaz Alam, Naseef Punnoth Poonkuzhi, Mohamed Saheer Kuruniyan, Mohd. Aamir Mirza and Zeenat Iqbal*


DOI: 10.2174/1386207325666220126102235
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Crosstalk between SARS-CoV-2 Infection and Type II Diabetes


Asim Azhar*, Wajihul Hasan Khan, Khaled Al-hosaini, Qamar Zia and Mohammad Amjad Kamal


DOI: 10.2174/1386207325666220315114332
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Construction and Validation of an Immune-Related lncRNA Prognosis Model for Thyroid Cancer


Zheng Li, Hui Wang, Xia Deng, Jing Zhang, Ling Wang, Wanyan Tang, Wenxin Youa and Weiqi Nian*


DOI: 10.2174/1386207325666220223123917
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Investigating the Mechanism of Shengmaiyin (Codonopsis pilosula) in the Treatment of Heart Failure Based on Network Pharmacology


Mo Kan*, Jifeng Wang, Sitong Ming, Xin Sui, Zhuang Zhang, Qing Yang, Xiaoran Liu, Jianan Lin, Yanhong Zhang, Qihang Pang, Yaxin Liu, Zhen Li, Na Li and Zhe Lin


DOI: 10.2174/1386207325666220221093415
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An Immune-Related Gene Signature Predicting Prognosis and Immunotherapy Response in Hepatocellular Carcinoma


Feng Zhang, Jialiang Cai, Keshu Hu, Wenfeng Liu, Shenxin Lu, Bei Tang, Miao Li, Weizhong Wu, Zhenggang Ren Ren and Xin Yin*


DOI: 10.2174/1386207325666220304115006
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Combinatorial Synthesis of Sulfonate Derivatives of α/β-Naphthol as Antioomycete Agents


Zhiping Che*, Song Zhang, Jiaxuan He, Di Sun, Xiaolong Guo, Yuanhao Li, Lina Zhu, Yihao Guo, Yibo Liu, Yuee Tian, Xiaobo Huang, Shengming Liu and Genqiang Chen


DOI: 10.2174/1386207325666220128120208
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Natural Products Against COVID-19 Inflammation: A Mini-Review


Simone Mendes Lopes, Herbert Igor de Medeiros, Marcus Tullius Scotti and Luciana Scotti*


DOI: 10.2174/1386207325666220128114547
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An Unfolded Protein Response-Related mRNA Signature Predicting the Survival and Therapeutic Effect of Hepatocellular Carcinoma


Zhixiong Su, Lei Wang, Xingte Chen, Xiaohong Zhong, Di Wang, Jianchao Wang, Lingdong Shao, Gang Chen and Junxin Wu*


DOI: 10.2174/1386207325666220204140925
View Abstract View on PubMed









Anti-proliferative Activity of Piper trioicum Leaf Essential Oil Based on Phytoconstituent Analysis, Molecular Docking and In Silico ADMET Approaches


Sudipta Jena, Asit Ray, Ambika Sahoo, Prabhat Kumar Das, Pradeep Kumar Kamila, Subrat Kumar Kar, Sanghamitra Nayak and Pratap Chandra Panda


DOI: 10.2174/1386207325666211222113239
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Can We Use mTOR Inhibitors for COVID-19 Therapy?


Ina Y. Aneva *, Solomon Habtemariam, Maciej Banach, Parames C. Sil , Kasturi Sarkar, Adeleh Sahebnasagh , Mohammad Amjad Kamal, Maryam Khayatkashani and Hamid Reza Khayat Kashani*


DOI: 10.2174/1386207325666211130140923
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miR-4295 Promotes the Malignant Progression of Gastric Cancer via Targeting PTEN


Xiaoyan Yang, Jing Yang, Yunlian Tang, Zhizhong Xie, Yang Zhang, Xiaoyong Lei* and Runliang Gan*


DOI: 10.2174/1386207325666211110095307
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COVID-19 Candidate Genes and Pathways Potentially Share the Association with Lung Cancer


Afnan M. Alnajeebi*, Hend F.H. Alharbi, Walla Alelwani, Nouf A. Babteen, Wafa Alansari, Ghalia Shamlan and Areej A. Eskandrani


DOI: 10.2174/1386207324666210712092649
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Polyphenolic Natural Products Active In Silico Against SARS-CoV-2 Spike Receptor Binding Domains and Non-structural Proteins - A Review


Mark Tristan Quimque, Kin Israel Notarte, Xela Amor Adviento, Mikhail Harvey Cabunoc, Von Novi de Leon, Felippe Steven Louis delos Reyes, Eiron John Lugtu, Joe Anthony Manzano, Sofia Nicole Monton, John Emmanuel Muñoz, Katherine Denise Ong, Delfin Yñigo Pilapil IV, Vito Roque III, Sophia Morgan Tan, Justin Allen Lim and Allan Patrick Macabeo*


DOI: 10.2174/1386207325666210917113207
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Synthesis and Antinociceptive Activity of Newly Modified Amine Analogs of Phencyclidine in Mice


Maryam Shokrollahi, Marjaneh Samadizadeh, Mohsen Khalili, Seyed Ali Sobhanian and Abbas Ahmadi*


DOI: 10.2174/1386207325666211005155128
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Network Pharmacology Analysis of the Effects of Achyranthis Bidentatae Radix Plus Semen Vaccariae on Migraine-induced Erectile Dysfunction


Jisheng Wang, Junlong Feng, Sheng Deng, Binghao Bao, Fanchao Meng, Hengheng Dai, Hongsheng Xu, Shizhen Wang, Bin Wang * and Haisong Li*


DOI: 10.2174/1386207324666210628105233
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FABP1 Gene Variant is Associated with Risk of Metabolic Syndrome


Reza Zare-Feyzabadi, Majid Mozaffari*, Majid Ghayour-Mobarhan* and Mohsen Valizadeh


DOI: 10.2174/1386207324666210603114434
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Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors


Naseer Maliyakkal*, Ipek Baysal, Anandkumar Tengli, Gulberk Ucar*, Mohammad Ali Abdullah Almoyad, Della Grace Thomas Parambi, Nicola Gambacorta, Orazio Nicolotti, Asmy Appadath Beeran and Bijo Mathew*


DOI: 10.2174/1386207324666210603125452
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3 CpG Methylation Biomarkers for the Diagnosis of Polycystic Ovary Syndrome (PCOS) in Blood Samples


Linling Xie, Xiaotao Jiang, Yi Chen, Cihui Huang, Yanfen Chen, Guantong Liu, Wenxi Sun, Lei Zeng* and Ruling Lu*


DOI: 10.2174/1386207321666210602170054
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Development of 2D, 3D-QSAR and Pharmacophore Modeling of Chalcones for the Inhibition of Monoamine Oxidase B


Bijo Mathew*, Chonny Herrera-Acevedo, Sanal Dev, T. M. Rangarajan, Mohamed Saheer Kuruniyan, Punnoth Poonkuzhi Naseef, Luciana Scotti and Marcus Tullius Scotti*


DOI: 10.2174/1386207324666210816125738
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Screening of Candidate Pathogenic Genes for Spontaneous Abortion Using Whole Exome Sequencing


Qingwen Zhu, Jia Liu, Li Chen, Yiwen Zhou, Tao Zhou, Wenjun Bian, Guohui Ding, Guang Li* and Jiayi Ding


DOI: 10.2174/1386207324666210628115715
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Effects of Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Fructose and Potassium Oxonate


Yu-Zhi Wang, Cong Zhou*, Li-Jie Zhu, Xing-Li-Shang He, Lin-Zi Li, Xiang Zheng, Wan-Feng Xu, Ying-Jie Dong, Bo Li, Qiao-Xian Yu*, Gui-Yuan Lv* and Su-Hong Chen*


DOI: 10.2174/1386207324666210528114345
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Systematic Optimisation of Microtiter Plate Lectin Assay to Improve Sialic Acid Linkage Detection


Nur Hanina Izzati Khairol Mokhtar, Ainulkhir Hussin, Aidil Abdul Hamid, Shahrul Hisham Zainal Ariffin and Muhammad Ashraf Shahidan*


DOI: 10.2174/1386207324666210802122538
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Xanthine Oxidase Inhibitory Activity of Euphorbia peplus L. Phenolics


Emadeldin M. Kamel, Noha A. Ahmed, Ashraf A. El-Bassuony, Omnia E. Hussein, Barakat Alrashdi, Sayed A. Ahmed, Al Mokhtar Lamsabhi, Hany H. Arab and Ayman M. Mahmoud*


DOI: 10.2174/1386207324666210609104456
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Combinatorial Synthesis of Novel 1-sulfonyloxy/acyloxyeugenol Derivatives as Fungicidal Agents


Genqiang Chen, Lina Zhu, Jiaxuan He, Song Zhang, Yuanhao Li, Xiaolong Guo, Di Sun, Yuee Tian, Shengming Liu, Xiaobo Huang and Zhiping Che*


DOI: 10.2174/1386207324666210813114829
View Abstract View on PubMed





Comparative Proteomic Analysis Reveals Novel Biomarkers for Gastric Cancer in South Indian Tamil Population


Ananthi Sivagnanam, Balasankar Thangasamy, Vignesh Nagarajan, Subeksha Govindarajan Ravi, Jeevitha Chithra Madhesh, Manikandan Athilinga Perumal, Premkumar Karunakaran and Megala Jayaraman*


DOI: 10.2174/1386207324666210603120320
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A Prognostic Nomogram for Predicting Overall Survival in Pediatric Wilms Tumor Based on an Autophagy-related Gene Signature


Longkai He, Xiaotong Wang, Ya Jin, Weipeng Xu, Jun Lyu, Yi Guan, Jingchao Wu, Shasha Han* and Guosheng Liu*


DOI: 10.2174/1386207324666210826143727
View Abstract









Virus as a Nanocarrier for Drug Delivery Redefining Medical Therapeutics - A Status Report


Sanjay Kumar Ojha*, Ritesh Pattnaik, Puneet Kumar Singh, Shubha Dixit, Snehasish Mishra, Sreyasi Pal and Subrat Kumar*


DOI: 10.2174/1386207323666201218115850
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Therapeutic Properties of PDMS Nanoparticles: A Promising New Drug Delivery Vehicle Against Inflammatory Conditions


Aiswarya Anilkumar Ajitha, Sri SivaKumar, Gayathri Viswanathan, Sabulal Baby and Prabath Gopalakrishnan Biju*


DOI: 10.2174/1386207324666210210112843
View Abstract View on PubMed



Editor-in-Chief

Gerald H. Lushington
LiS Consulting
Lawrence, KS
(USA)
Biography
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Journal History

Combinatorial Chemistry & High Throughput Screening Journal was launched in 1998. Dr. Gerald H. Lushington serves as the Editor-in-Chief of the journal.

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