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Combinatorial Chemistry & High Throughput Screening

Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 23, 10 Issues, 2020
ISSN: 1875-5402 (Online)
ISSN: 1386-2073 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Articles Ahead of Print

Effect of visnagin on altered steroidogenesis and spermatogenesis, and testicular injury induced by the heavy metal lead


Jamaan S. Ajarem, Ahmad K. Hegazy, Gamal A. Allam, Ahmed A. Allam, Saleh N. Maodaa and Ayman M. Mahmoud*


DOI: 10.2174/1386207323999200918124639
View Abstract


Anti-Respiratory Syncytial Virus Mechanism of Houttuynia cordata Thunb Exploration based on Network Pharmacology


Haitao Du, Jie Ding, Ping Wang, Guisheng Zhang, Dandan WANG*, Qingyun Ma*, Na Li and Tiefeng Sun*


DOI: 10.2174/1386207323999200918123631
View Abstract


Synthesis, characterization, antitubercular and anti-inflammatory activity of new pyrazolo[3,4-d]pyrimidines


Ravindra Kulkarni*, Krishna Kompalli, Naveen Gaddam, Chandrashekar V, Bikshupati Darna, Achaiah Garlapati, Dileep Kumar and Baswaraju Machha


DOI: 10.2174/1386207323999200918114905
View Abstract


Carbon Nano Tubes: Novel drug delivery system in amelioration of Alzheimer’s disease


Jayanti Mishra, Bhumika Kumar, Mukesh Pandey, Faheem Hyder Pottoo, Faizana Fayaz, Firdos Alam Khan and P.K. Sahoo*


DOI: 10.2174/1386207323999200918112538
View Abstract



A potential MRI agent and an anticancer drug encapsulated within CPMV virus-like particles


Alaa A A Aljabali*, Lorca Alzoubi, Yassmen Hamzat, Alaa Alqudah, Mohammad A. Obeid, Mazhar S. Al Zoubi, Raed M Ennab, Walhan Alshaer, Khaled Albatayneh, Bahaa Al‑Trad, Dana A. Alqudah, Dinesh Kumar Chellappan, Gaurav Gupta, Murtaza M. Tambuwala, Dua Kamal and David J Evans


DOI: 10.2174/1386207323666200914110012
View Abstract









Expression and prognostic significance of the MMP family molecules in bladder cancer


Chong Shen, La Da, Zhouliang Wu, Yujie Wang, Shen Gao, Dawei Tian and Hailong Hu*


DOI: 10.2174/1386207323666200917103253
View Abstract








Transcriptome-wide Association Study Identifies Genetically Dysregulated Genes in Diabetic Neuropathy


Danfeng Lan, Hong-Yan Jiang, Xiaoyang Su, Yan Zhao, Sicheng Du, Ying Li, Rui Bi, Deng-Feng Zhang and Qiuping Yang*


DOI: 10.2174/1386207323666200808173745
View Abstract View on PubMed



Astaxanthin prevents lung injury due to hyperoxia and inflammation


Hasan Akduman*, Cüneyt Tayman, Ufuk Çakir, Esra Çakir, Dilek Dilli, Tuğba Taşkin Türkmenoğlu and Ataman Gönel


DOI: 10.2174/1386207323666200915092012
View Abstract



Protective Effects of Astaxanthin on Nephrotoxicity in Rats with Induced Renovascular Occlusion


Erkan Arslan, Hakan Turk*, Murat Caglayan, Tugba Taskin Turkmenoglu, Ataman Gonel and Cuneyt Tayman


DOI: 10.2174/1386207323666200914104432
View Abstract




13-lncRNAs Signature to Improve Diagnostic and Prognostic Prediction of Hepatocellular Carcinoma


Xinxin Zhang, Jia Yu, Juan Hu, Fang Tan, Juan Zhou, Xiaoyan Yang, Zhizhong Xie, Huifang Tang, Sen Dong and Xiaoyong Lei*


DOI: 10.2174/1386207323666200914095616
View Abstract







Protective role of Morus nigra leaf extracts against murine infection with Eimeria papillata


Felwa A. Thagfan*, Wafa A. Al-Megrin, Esam M. Al-Shaebi, Saleh Al-Quraishy and Mohamed A. Dkhil


DOI: 10.2174/1386207323666200903152811
View Abstract


Potential Leads from Liquorice against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies


Saurabh K. Sinha, Satyendra K. Prasad, Md Ataul Islam, Sushil K. Chaudhary, Shashikant Singh and Anshul Shakya*


DOI: 10.2174/1386207323999200817103148
View Abstract View on PubMed


DSARna: RNA Secondary Structure Alignment Based on Digital Sequence Representation


Longjian Gao, Chengzhen Xu*, Wangan Song, Feng Xiao, Xiaomin Wu, Li Shi, Yuxuan Sun and Jun Li


DOI: 10.2174/1386207323666200811100338
View Abstract View on PubMed






Variations in Mineral/heavy metals profiling and preventive role of trichomes in Peach Fruits treated with CaC2


Muhammad Irfan, Safdar Abbas, Beenish Jehan Azhar, Shakeel Ahmad, Hafsa Muhammad*, Ishaq Ahmed, Javed Hussain and Samina N Shakeel


DOI: 10.2174/1386207323666200808175723
View Abstract View on PubMed



Discovery of Potent SARS-CoV-2 Inhibitors from Approved Antiviral Drugs via Docking and Virtual Screening


Samir Chtita *, Assia Belhassan, Adnane Aouidate, Salah Belaidi, Mohammed Bouachrine and Tahar Lakhlifi


DOI: 10.2174/1386207323999200730205447
View Abstract View on PubMed


Exploring the Mechanism of Lingzhu San in Treating Febrile Seizures by Using Network Pharmacology


Xiao Zhou, Xiao-Fei Zhang, Dong-Yan Guo, Yan-Jun Yang, Lin Liu, Lin Wang, Xue Zhang, Jiang-Xue Cheng, Jun-Bo Zou and Ya-Jun Shi*


DOI: 10.2174/1386207323666200902144348
View Abstract


Interpretable SMILES-based QSAR model of inhibitory activity of sirtuins 1 and 2


Apilak Worachartcheewan*, Alla P. Toropova, Andrey A. Toropov, Reny Pratiwi, Virapong Prachayasittikul and Chanin Nantasenamat


DOI: 10.2174/1386207323666200902141907
View Abstract




Osteopontin is a prognostic factor in patients with advanced gastric cancer


Ozan Yazici*, Mutlu Dogan, Guze Ozal, Sedef Hande Aktas, Ahmet Demirkazik, Gungor Utkan, Filiz Cay Senler, Fikri Icli and Hakan Akbulut


DOI: 10.2174/1386207323666200902135349
View Abstract






Cervical Cancer Diagnosis: Insights into Biochemical Biomarkers and Imaging techniques


Fatemeh Tavakoli, Sara Sadat Khatami, Fatemeh Momeni, Javid Azadbakht and Faezeh Ghasemi*


DOI: 10.2174/1386207323666200901101955
View Abstract






A Five-microRNA Signature as Risk Stratification System in Uterine Corpus Endometrial Carcinoma


Zhichao Chen, Xiaoyuan Huang, Yufeng Lv*, Yuan Fang, Lili Pan, Zuhuan Gan, Zhong Huang and Wenhao Wei


DOI: 10.2174/1386207323999200730211227
View Abstract View on PubMed








Lead Finding from Selected Flavonoids with Antiviral (SARS-CoV-2) Potentials against COVID-19: An in-silico Evaluation


Uma Sankar Gorla*, GSN Koteswara Rao, Uma Sankar Kulandaivelu, Rajasekhar Reddy Alavala and Siva Prasad Panda


DOI: 10.2174/1386207323999200818162706
View Abstract









Pollen Beads: A New Carrier for Propolis Active Compounds


Şaban Keskin*, Boryana Trusheva, Merve Keskin, Milena Popova, Sevgi Kolaylı and Vassya Bankova


DOI: 10.2174/1386207323666200720102651
View Abstract View on PubMed


Investigating the Levels of Brain-Specific Proteins in Hydrocephalus Patients


Ahmet Guzelcicek*, Ataman Gönel, Ismail Koyuncu, Gulyara Cigdem, Dogan Kose, Mehmet Karadag and Dursun Cadirci


DOI: 10.2174/1386207323666200720093245
View Abstract View on PubMed




Pathophysiological Effects of Sulfur Mustard on Skin and its Current Treatments: Possible Application of Phytochemicals


Mehdi Hassanpour, Fateme Hajihassani, Mina Abdollahpourasl, Omid Cheraghi, Nasser Aghamohamadzade, Reza Rahbargazi, Mohammad Nouri, Younes Pilehvar-Soltanahmadi, Nosratollah Zarghami, Abolfazl Akbarzadeh, Yunes Panahi and Amirhossein Sahebkar*


DOI: 10.2174/1386207323666200717150414
View Abstract View on PubMed















Design and Synthesis of an Aniline Derivative with Biological Activity on Heart Failure


Garcimarero-Espino E. Alejandra, Figueroa-Valverde Lauro*, Rosas-Nexticapa Marcela, Lopez-Ramos Maria, Diaz Cedillo Francisco, Mateu-Armand Virginia and Ortiz-Ake Yazmin


DOI: 10.2174/1386207323666200709163008
View Abstract View on PubMed






Rhodamine B - as New Chromophore for the Determination of Melatonin in Biological, Food, and Pharmaceutical Samples


Alexandrina Lungu-Moscalu, Catalina Cioates Negut, Cristina Stefanov, Raluca-Ioana Stefanvan Staden*, Andrei A. Bunaciu and Jacobus Frederick Van Staden


DOI: 10.2174/1386207323666200628111958
View Abstract View on PubMed








A Systems Biology Approach for miRNA-mRNA Expression Patterns Analysis in Rheumatoid Arthritis


Fataneh Tavasolian, Ahmad Zavaran Hosseini, Sara Soudi, Mahmood Naderi and Amirhossein Sahebkar*


DOI: 10.2174/1386207323666200605150024
View Abstract View on PubMed








Correlations Between Overexpression of SOX2OT Long Non-coding RNA and Susceptibility to Breast Cancer


Mina Dehghani-Samani, Naiemeh Hassanzadeh, Hamidreza Kabiri, Marzieh Jafari, Matineh Rahmani Ghaleh Shahrokhi, Maryam Jafari Chermahini, Arvand Akbari, Esmat Noshadi, Esmaeil Mahmoudi and Amela Jusic*


DOI: 10.2174/1386207323666200514075042
View Abstract View on PubMed




Flaxseed for Health and Disease: Review of Clinical Trials


Mersedeh Shayan, Safa Kamalian, Amirhossein Sahebkar* and Zahra Tayarani Najaran


DOI: 10.2174/1386207323666200521121708
View Abstract View on PubMed


In silico and In vivo Evaluation of Oxidative Stress Inhibitors Against Parkinson's Disease using the C. elegans Model


Pradeep Hanumanthappa, Arpitha Ashok, Inderjit Prakash, Carmel I. Priya, Julie Zinzala, Vidya V. Marigowda and Aparna H. Sosalegowda*


DOI: 10.2174/1386207323666200514074128
View Abstract View on PubMed








In vitro and In silico Xanthine Oxidase Inhibitory Activity of Selected Phytochemicals Widely Present in Various Edible Plants


Arshad Mehmood, Ashfaq Ur Rehman, Muhammad Ishaq, Liang Zhao, Jiayi Li, Muhammad Usman, Lei Zhao, Abdur Rehman, Oumeddour Dounya Zad and Chengtao Wang*


DOI: 10.2174/1386207323666200428075224
View Abstract View on PubMed


T-cell Epitope-based Vaccine Design for Nipah Virus by Reverse Vaccinology Approach


Praveen Kumar Posa Krishnamoorthy*, Sekar Subasree, Udhayachandran Arthi, Mobashir Imam, Chirag Gowda and Prasanna DR


DOI: 10.2174/1386207323666200427114343
View Abstract View on PubMed







Integrating Bioinformatics Strategies in Cancer Immunotherapy: Current And Future Perspectives


Houda N. Washah, Elliasu Y. Salifu, Opeyemi Soremekun, Ahmed A. Elrashedy, Geraldene Munsamy, Fisayo A. Olotu and Mahmoud E.S. Soliman*


DOI: 10.2174/1386207323666200427113734
View Abstract View on PubMed



GC-MS Based Metabolic Profiling of Parkinson’s Disease with Glutathione S-transferase M1 and T1 Polymorphism in Tunisian Patients


Amal Rebai*, Tuba Reçber, Emirhan Nemutlu, Chahra Chbili, Sevinç Kurbanoglu, Sedef Kir, Sana Ben Amor, Sibel A Özkan and Saad Saguem


DOI: 10.2174/1386207323666200428082815
View Abstract View on PubMed















Editor-in-Chief

Gerald H. Lushington
LiS Consulting, Lawrence
KS
(USA)

Biography
View Full Editorial Board

Journal History

Combinatorial Chemistry & High Throughput Screening Journal was launched in 1998. Dr. Gerald H. Lushington serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.33

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