Bentham Science Logo

CNS & Neurological Disorders - Drug Targets

Formerly: Current Drug Targets - CNS & Neurological Disorders

Volume 18, 10 Issues, 2019
ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)
This journal supports open access

Ranking and Category

  • 150th of 267 in

    Neurosciences

  • 119th of 267 in

    Pharmacology & Pharmacy

Order Your Article Before Print

Aims & Scope

CNS & Neurological Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in neurological and central nervous system (CNS) disorders e.g. disease specific proteins, receptors, enzymes, genes.

CNS & Neurological Disorders - Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of CNS & neurological drug targets. The journal also accepts for publication original research articles, letters, reviews and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for neurological and CNS drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

CNS & Neurological Disorders - Drug Targets

,

Volume 18

-

Number 6



Biography   Open Access



Review Article



Review Article

Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review

, 18(6): 432 - 445

Bijo Mathew*, Della Grace Thomas Parambi, Vishnu Sankar Sivasankarapillai, Md. Sahab Uddin, Jerad Suresh, Githa Elizabeth Mathew, Monu Joy, Akash Marathakam and Sheeba Varghese Gupta


DOI: 10.2174/1871527318666190610111246


Review Article



Systemic Review Article

Suicide in Parkinson’s Disease: A Systematic Review

, 18(6): 466 - 477

Isabella Berardelli, Daniele Belvisi, Adele Nardella, Giulia Falcone, Dorian A. Lamis, Giovanni Fabbrini, Alfredo Berardelli, Paolo Girardi and Maurizio Pompili*


DOI: 10.2174/1871527318666190703093345


Systemic Review Article

Implications of Vitamin D in Multiple Sclerosis and Other Neurodegenerative Processes: Bibliometric Analysis and Systematic Review

, 18(6): 478 - 490

Javier Caballero-Villarraso*, María J. Jiménez-Jiménez, Begoña M. Escribano, Eduardo Agüera, Abel Santamaría and Isaac Túnez*


DOI: 10.2174/1871527318666190703102330


Clinical Trial   Open Access



Clinical Trial

The Effect of Vitamin D3 Supplementation on Serum BDNF, Dopamine, and Serotonin in Children with Attention-Deficit/Hyperactivity Disorder

, 18(6): 496 - 501

Marzieh Seyedi, Fatemeh Gholami, Mahsa Samadi, Mahmoud Djalali, Mohammad Effatpanah*, Mir Saeed Yekaninejad, Rezvan Hashemi, Mina Abdolahi, Maryam Chamari and Niyaz Mohammadzadeh Honarvar


DOI: 10.2174/1871527318666190703103709


CNS & Neurological Disorders - Drug Targets , Volume 18 (2019) - Number 8


This issue is in progress but contains articles that are final and fully citable.

CNS & Neurological Disorders - Drug Targets , Volume 18 (2019) - Number 7


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print



Pharmacotherapy of Down’s Syndrome: When and Which?


Seyed Khosrow Tayebati*, Alessandro Cecchi, Ilenia Martinelli, Elisa Carboni and Francesco Amenta


DOI: 10.2174/1871527318666191114092924
View Abstract




Cannabidiol Partially Blocks the Excessive Sleepiness in Hypocretindeficient Rats: Preliminary Data


Eric Murillo-Rodríguez*, Diana Millán-Aldaco, Marcela Palomero-Rivero, Daniela Morales-Lara, Raphael Mechoulam and René Drucker-Colín


DOI: 10.2174/1871527318666191021143300
View Abstract View on PubMed





Gut Microbiome: Lactation, Childbirth, Lung Dysbiosis, Animal Modeling, Stem Cell Treatment, and CNS Disorders


Sydney Corey, Lauren Kvederis, Chase Kingsbury, Brooke Bonsack, Paul R. Sanberg, Vanessa Castelli, Jea-Young Lee and Cesar V. Borlongan*


DOI: 10.2174/1871527318666191021145252
View Abstract View on PubMed


Published Contents

Editor's Choice

The Effect of Vitamin D3 Supplementation on Serum BDNF, Dopamine, and Serotonin in Children with Attention-Deficit/Hyperactivity Disorder

, 2019; 18(6): 496 - 501

Marzieh Seyedi, Fatemeh Gholami, Mahsa Samadi, Mahmoud Djalali, Mohammad Effatpanah*, Mir Saeed Yekaninejad, Rezvan Hashemi, Mina Abdolahi, Maryam Chamari and Niyaz Mohammadzadeh Honarvar


DOI: 10.2174/1871527318666190703103709






Xuesaitong May Protect Against Ischemic Stroke by Modulating Microglial Phenotypes and Inhibiting Neuronal Cell Apoptosis via the STAT3 Signaling Pathway

, 2019; 18(2): 115 - 123

Fangfang Li, Haiping Zhao, Ziping Han, Rongliang Wang, Zhen Tao, Zhibin Fan, Sijia Zhang, Guangwen Li, Zhigang Chen* and Yumin Luo*


DOI: 10.2174/1871527317666181114140340



Motor Recovery after Chronic Spinal Cord Transection in Rats: A Proof-of-Concept Study Evaluating a Combined Strategy

, 2019; 18(1): 52 - 62

Antonio Ibarra*, Erika Mendieta-Arbesú, Paola Suarez-Meade, Elisa García-Vences, Susana Martiñón, Roxana Rodriguez-Barrera, Joel Lomelí, Adrian Flores-Romero, Raúl Silva-García, Vinnitsa Buzoianu-Anguiano, Cesar V. Borlongan and Tamara D. Frydman


DOI: 10.2174/1871527317666181105101756




Autophagy and Mitochondria: Targets in Neurodegenerative Disorders

, 2018; 17(9): 696 - 705

Ashutosh Kumar*, Amruta Dhawan, Alknanda Kadam and Akshada Shinde


DOI: 10.2174/1871527317666180816100203



Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders

, 2018; 17(8): 626 - 639

Heidi Ormstad*, Vesna Bryn, Robert Verkerk, Ola H. Skjeldal, Bente Halvorsen, Ola Didrik Saugstad, Jorn Isaksen and Michael Maes


DOI: 10.2174/1871527317666180720163221



Light-Emitting Diode (LED) Therapy Attenuates Neurotoxicity of Methanol-Induced Memory Impairment and Apoptosis in The Hippocampus

, 2018; 17(7): 528 - 538

Amir Ghanbari, Kazem Zibara, Sepideh Salari, Majid Ghareghani, Parastou Rad, Wael Mohamed, Elham Ebadi, Mohamad Malekzadeh and Hamdallah Delaviz*


DOI: 10.2174/1871527317666180703111643



Open Access Articles


Fire Needle Acupuncture Regulates Wnt/ERK Multiple Pathways to Promote Neural Stem Cells to Differentiate into Neurons in Rats with Spinal Cord Injury

, 2019; 18(3): 245 - 255

Jiachun Xu, Suli Cheng, Zhaohua Jiao, Zhiheng Zhao, Zhimin Cai, Nan Su, Baohong Liu, Zhen Zhou* and Yan Li*




Oleanolic Acid Ameliorates Aβ25-35 Injection-induced Memory Deficit in Alzheimer’s Disease Model Rats by Maintaining Synaptic Plasticity

, 2018; 17(5): 389 - 399

Kai Wang, Weiming Sun, Linlin Zhang, Wei Guo, Jiachun Xu, Shuang Liu, Zhen Zhou and Yulian Zhang*




Physiological and Morphological Principles Underpinning Recruitment of the Cerebellar Reserve

, 2018; 17(3): 184 - 192

Shinji Kakei*, Takahiro Ishikawa, Jongho Lee, Takeru Honda and Donna S. Hoffman




Demonstration of Biological and Immunological Equivalence of a Generic Glatiramer Acetate

, 2017; 16(6): 714 - 723

Josephine D`Alessandro, Kevin Garofalo, Ganlin Zhao, Christopher Honan, Jay Duffner, Ishan Capila, Ian Fier, Ganesh Kaundinya, Daniel Kantor and Tanmoy Ganguly*




Nanomaterials for Neurology: State-of-the-Art

, 2016; 15(10): 1306 - 1324

María Fernanda Veloz-Castillo, Rachel M. West, Jessica Cordero-Arreola, Oscar Arias-Carrión and Miguel A. Méndez-Rojas




The Potential of Nasal Oxytocin Administration for Remediation of Autism Spectrum Disorders

, 2016; 15(5): 564 - 577

Yuko Okamoto, Makoto Ishitobi, Yuji Wada and Hirotaka Kosaka





The Effects of Testosterone Supplementation on Cognitive Functioning in Older Men.

, 2016; 15(3): 337 - 343

Eka J. Wahjoepramono, Prita R. Asih, Vilia Aniwiyanti, Kevin Taddei, Satvinder S. Dhaliwal, Stephanie J. Fuller, Jonathan Foster, Malcolm Carruthers, Giuseppe Verdile, Hamid R Sohrabi and Ralph N. Martins




Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid

, 2015; 14(10): 1343 - 1349

Evgeny E. Akkuratov, Jian Wu, David Sowa, Zahoor A. Shah and Lijun Liu






The Role of Neuroimaging in Our Understanding of the Suicidal Brain

, 2013; 12(7): 921 - 929

Stefanie Desmyter, Stijn Bijttebier and Kees van Heeringen







Most Cited Articles

Review Article

Oxidative stress: Major threat in traumatic brain injury

, 2018; 17(9): 689-695.

Nidhi Khatri, Manisha Thakur, Vikas Pareek, Sandeep Kumar, Sunil Sharma and Ashok Kumar Datusalia*


DOI: 10.2174/1871527317666180627120501


Review Article

Dl-3-n-butylphthalide (NBP): A promising therapeutic agent for ischemic stroke

, 2018; 17(5): 338-347.

Shan Wang, Fei Ma, Longjian Huang, Yong Zhang, Yuchen Peng, Changhong Xing, Yipu Feng, Xiaoliang Wang* and Ying Peng*


DOI: 10.2174/1871527317666180612125843


Research Article

Protective effect of kaempferol on the transgenic drosophila model of Alzheimer’s disease

, 2018; 17(6): 421-429.

Tanveer Beg, Smita Jyoti, Falaq Naz, Rahul, Fahad Ali, Syed Kashif Ali, Ahmed Mohamed Reyad and Yasir Hasan Siddique*


DOI: 10.2174/1871527317666180508123050


General Review Article

The underlying role of oxidative stress in neurodegeneration: A mechanistic review

, 2018; 17(3): 207-215.

Habib Yaribeygi, Yunes Panahi*, Behjat Javadi and Amirhossein Sahebkar*


DOI: 10.2174/1871527317666180425122557




Review Article

Neurotransplantation therapy and cerebellar reserve

, 2018; 17(3): 172-183.

Jan Cendelin, Hiroshi Mitoma* and Mario Manto


DOI: 10.2174/1871527316666170810114559


Review Article

Autophagy and mitochondria: Targets in neurodegenerative disorders

, 2018; 17(9): 696-705.

Ashutosh Kumar*, Amruta Dhawan, Alknanda Kadam and Akshada Shinde


DOI: 10.2174/1871527317666180816100203


Research Article

A novel combination of ω-3 fatty acids and nano-curcumin modulates interleukin-6 gene expression and high sensitivity C-reactive protein serum levels in patients with migraine: A randomized clinical trial study

, 2018; 17(6): 430-438.

Mina Abdolahi, Payam Sarraf, Mohammad Hassan Javanbakht, Niyaz Mohammadzadeh Honarvar, Mahsa Hatami, Neda Soveyd, Abbas Tafakhori, Mohsen Sedighiyan, Mona Djalali, Arash Jafarieh, Yousef Masoudian and Mahmoud Djalali*


DOI: 10.2174/1871527317666180625101643


Review Article

Cognitive impact of cerebellar damage: Is there a future for cognitive rehabilitation?

, 2018; 17(3): 199-206.

Kim van Dun, Frank V. Overwalle, Mario Manto* and Peter Marien


DOI: 10.2174/1871527317666180110125043


Research Article

Development of a nasal donepezil-loaded microemulsion for the treatment of Alzheimer’s disease: In vitro and Ex vivo characterization

, 2018; 17(1): 43-53.

Lupe C. Espinoza, Marisol Vacacela, Beatriz Clares*, Maria Luisa Garcia, Maria-Jose Fabrega and Ana C. Calpena


DOI: 10.2174/1871527317666180104122347


Review Article

Nf-κb as a key mediator of brain inflammation in Alzheimer’s disease

, 2019; 18(1): 3-10.

Chul Ju Hwang, Dong-Young Choi, Mi Hee Park and Jin Tae Hong*


DOI: 10.2174/1871527316666170807130011


Review Article

Therapeutic advancement in alzheimer disease: New hopes on the horizon?

, 2018; 17(8): 571-589.

Ajeet Singh, Abshar Hasan, Sakshi Tiwari and Lalit M. Pandey*


DOI: 10.2174/1871527317666180627122448



Review Article

C-Abl inhibition; A novel therapeutic target for Parkinson’s disease

, 2018; 17(1): 14-21.

Abdelrahman Ibrahim Abushouk, Ahmed Negida*, Rasha Abdelsalam Elshenawy, Hossam Zein, Ali M. Hammad, Ahmed Menshawy and Wael M.Y. Mohamed


DOI: 10.2174/1871527316666170602101538



Most Accessed Articles


Hydrolyzed Rutin Decreases Worsening of Anaplasia in Glioblastoma Relapse

, 2019; 18(5): 405-412.

Carlos Tadeu Parisi de Oliveira, Renato Colenci, Cesar Cozar Pacheco, Patrick Moro Mariano, Paula Ribeiro do Prado, Gustavo Pignatari Rosas Mamprin, Maycon Giovani Santana, Alessandra Gambero, Patrícia de Oliveira Carvalho and Denise Gonçalves Priolli*


DOI: 10.2174/1871527318666190314103104






The Effect of Vitamin D3 Supplementation on Serum BDNF, Dopamine, and Serotonin in Children with Attention-Deficit/Hyperactivity Disorder

, 2019; 18(6): 496-501.

Marzieh Seyedi, Fatemeh Gholami, Mahsa Samadi, Mahmoud Djalali, Mohammad Effatpanah*, Mir Saeed Yekaninejad, Rezvan Hashemi, Mina Abdolahi, Maryam Chamari and Niyaz Mohammadzadeh Honarvar


DOI: 10.2174/1871527318666190703103709



The Associations between Central Nervous System Diseases and Haemostatic Disorders

, 2019; 18(4): 307-316.

Maria Podsiedlik*, Magdalena Markowicz-Piasecka, Elżbieta Mikiciuk-Olasik and Joanna Sikora


DOI: 10.2174/1871527318666190314101946





Editor-in-Chief

Cesar V. Borlongan
Department of Neurosurgery and Brain Repair
University of South Florida Morsani College of Medicine
Tampa, FL
USA

Biography View Full Editorial Board

Journal History

Current Drug Targets - CNS & Neurological Disorders was launched in 2002 and later renamed in 2006 as CNS & Neurological Disorders - Drug Targets.
Track Your Manuscript:


Scopus CiteScore Metrics: 2.05

Related Journals

Related eBooks

eBooks Catalog