Contents

CNS & Neurological Disorders - Drug Targets , Volume 9 - Number 6

Commentary

, 9(6): 667

Oscar Arias-Carrion and Maria Stamelou


DOI: 10.2174/187152710793237467




Editorial [Hot Topic: Drug Discovery for CNS Disorders: From Bench to Bedside (Guest Editor: Tiago Fleming Outeiro)]

, 9(6): 668

Aleksey G. Kazantsev and Tiago Fleming Outeiro


DOI: 10.2174/187152710793237395




Development of Novel Genomic Blood Biomarkers for Neurodegenerative Diseases

, 9(6): 669 - 678

Fran Borovecki and Mario Habek


DOI: 10.2174/187152710793237476




Organelle Stress Sensors and Cell Death Mechanisms in Neurodegenerative Diseases

, 9(6): 679 - 692

Ricardo J.S. Viana, Maria B. Fonseca, Rita M. Ramalho, Ana F. Nunes and Cecilia M.P. Rodrigues


DOI: 10.2174/187152710793237511




Phenotypic Screening Strategies for Neurodegenerative Diseases: A Pathway to Discover Novel Drug Candidates and Potential Disease Targets or Mechanisms

, 9(6): 693 - 700

R. M. Pruss


DOI: 10.2174/187152710793237377




Autophagy in the Central Nervous System: Implications for Neurodegenerative Disorders

, 9(6): 701 - 719

Maria Xilouri and Leonidas Stefanis


DOI: 10.2174/187152710793237421




Wnt Signalling is a Relevant Pathway Contributing to Amyloid Beta-Peptide-Mediated Neuropathology in Alzheimers Disease

, 9(6): 720 - 726

Odete A.B. da Cruz e Silva, Ana Gabriela Henriques, Sara Catarina Timoteo Santos Domingues and Edgar F. da Cruz e Silva


DOI: 10.2174/187152710793237458




Tau Phosphorylation and Aggregation as a Therapeutic Target in Tauopathies

, 9(6): 727 - 740

Nahuai Badiola, Marc Suarez-Calvet and Alberto Lleo


DOI: 10.2174/187152710793237403




Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics

, 9(6): 741 - 753

S. K. Kalia, L. V. Kalia and P. J. McLean


DOI: 10.2174/187152710793237386




Neurotrophic Factors as a Protective Strategy in Parkinsons Disease

, 9(6): 754 - 763

Maria Jose Diogenes and Tiago Fleming Outeiro


DOI: 10.2174/187152710793237449




Diagnosis, Pathogenesis and Therapeutic Targets in Amyotrophic Lateral Sclerosis

, 9(6): 764 - 778

Julia Costa, Catarina Gomes and Mamede de Carvalho


DOI: 10.2174/187152710793237502




Genetic Determinants of Amyotrophic Lateral Sclerosis as Therapeutic Targets

, 9(6): 779 - 790

Daryl A. Bosco and John E. Landers


DOI: 10.2174/187152710793237494




Targeting Kynurenine 3-Monooxygenase (KMO): Implications for Therapy in Huntingtons Disease

, 9(6): 791 - 800

Mathuravani A. Thevandavakkam, Robert Schwarcz, Paul J. Muchowski and Flaviano Giorgini


DOI: 10.2174/187152710793237430




Schwann Cells as a Therapeutic Target for Peripheral Neuropathies

, 9(6): 801 - 806

Helmar C. Lehmann and Ahmet Hoke


DOI: 10.2174/187152710793237412




Are Anti-Angiogenic Drugs Useful in Neurodegenerative Disorders?

, 9(6): 807 - 812

Daniele De Filippis, Mariateresa Cipriano, Giuseppe Esposito, Caterina Scuderi, Luca Steardo and Teresa Iuvone


DOI: 10.2174/187152710793237485




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