CNS & Neurological Disorders - Drug Targets
Formerly: Current Drug Targets - CNS & Neurological Disorders
Volume 20, 10 Issues, 2021
ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)
This journal supports open access
ISSN: 1996-3181 (Online)
ISSN: 1871-5273 (Print)
This journal supports open access
Contents
CNS & Neurological Disorders - Drug Targets , Volume 16 - Number 7
Biography Open Access
Review Article
Recent Advances on the Role of Neurogenesis in the Adult Brain: Therapeutic Potential in Parkinson's and Alzheimer's Diseases
, 16(7): 740 - 748Khaled Radad*, Rudolf Moldzio, Mubarak Al-Shraim, Barbara Kranner, Christopher Krewenka and Wolf-Dieter Rausch
DOI: 10.2174/1871527316666170623094728
Recent Advances on the Role of Neurogenesis in the Adult Brain: Therapeutic Potential in Parkinson's and Alzheimer's Diseases
Review Article
The Role of Innate Immune System Receptors in Epilepsy Research
, 16(7): 749 - 762Jessica Cordero-Arreola, Rachel M. West, Julieta Mendoza-Torreblanca, Edna Mendez-Hernandez, Jose Salas-Pacheco, Manuel Menendez-Gonzalez, Rafael C. Freire, Sergio Machado, Eric Murillo-Rodriguez, Antonio E. Nardi and Oscar Arias-Carrion*
DOI: 10.2174/1871527316666170725145549
The Role of Innate Immune System Receptors in Epilepsy Research
Review Article
Natural Steroids and Androgen Antagonists used as Neuroprotection in Common Neurological Disorders
, 16(7): 763 - 771David Calderon Guzman, Hugo Juarez Olguin*, Ernestina Hernandez Garcia, Monica Punzo Soto, Mayra Santillan Garcia and Gerardo Barragan Mejia
DOI: 10.2174/1871527316666170714121654
Natural Steroids and Androgen Antagonists used as Neuroprotection in Common Neurological Disorders
Research Article
Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats
, 16(7): 772 - 780Carmen Rubio, Artemio Rosiles-Abonce, Cristina Trejo-Solis, Moises Rubio-Osornio, Cesar Mendoza, Veronica Custodio, Juan C Martinez-Lazcano, Edith Gonzalez and Carlos Paz*
DOI: 10.2174/1871527316666170117114513
Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats
Research Article
Granulocyte Colony-Stimulating Factor Attenuates Blood-Brain Barrier Damage and Improves Cognitive Function in Spontaneously Hypertensive Rats
, 16(7): 781 - 788Xin Wei, Yan Xu*, Yanling Jin, Hongliang Feng, Yunyue Xiao and Shouquan Dong
DOI: 10.2174/1871527316666170207155730
Granulocyte Colony-Stimulating Factor Attenuates Blood-Brain Barrier Damage and Improves Cognitive Function in Spontaneously Hypertensive Rats
Research Article
Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Metaanalysis of Randomized Controlled Trials
, 16(7): 789 - 799Ahmed Elmaraezy, Abdelrahman Ibrahim Abushouk, Soha Saad, Moutaz Eltoomy, Osama Mahmoud, Hossam Mahmoud Hassan, Ahmed Aboelmakarem, Ahmed Aboel Fotoh, Farah Althaher, Nguyen Tien Huy* and Kenji Hirayama
DOI: 10.2174/1871527315666161213110104
Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Metaanalysis of Randomized Controlled Trials
Research Article
Advanced Structure-activity Relationships Applied to Mentha spicata L. Subsp. spicata Essential Oil Compounds as AChE and NMDA Ligands, in Comparison with Donepezil, Galantamine and Memantine – New Approach in Brain Disorders Pharmacology
, 16(7): 800 - 811Speranta Avram, Maria Mernea*, Eyup Bagci, Lucian Hritcu, Livia-Cristina Borcan and Dan Florin Mihailescu
DOI: 10.2174/1871527316666170113115004
Advanced Structure-activity Relationships Applied to Mentha spicata L. Subsp. spicata Essential Oil Compounds as AChE and NMDA Ligands, in Comparison with Donepezil, Galantamine and Memantine – New Approach in Brain Disorders Pharmacology
Research Article
Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome
, 16(7): 812 - 819Sandra Guidi, Patrizia Bianchi, Fiorenza Stagni, Andrea Giacomini, Marco Emili, Stefania Trazzi, Elisabetta Ciani and Renata Bartesaghi*
DOI: 10.2174/1871527315666160801143108
Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome
Research Article
Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses
, 16(7): 820 - 827Mohammad A. Kamal*, Shazi Shakil, Muhammad S. Nawaz, Qian-sheng Yu, David Tweedie, Y. Tan, Xianqin Qu and Nigel H. Greig*
DOI: 10.2174/1871527316666170207160606
Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses
Research Article
Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway
, 16(7): 828 - 836Xing-tong Li, Zhang Liang, Tong-tong Wang, Jin-wei Yang, Wei Ma, Shi-kang Deng, Xian-bin Wang, Yun-fei Dai, Jian-hui Guo* and Li-yan Li*
DOI: 10.2174/1871527316666170518170422
Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway
Research Article
The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex
, 16(7): 837 - 845Mariola Herbet*, Aleksandra Szopa, Sylwia Wosko, Anna Serefko, Magdalena Izdebska, Monika Gawronska-Grzywacz, Iwona Piatkowska-Chmiel, Martyna Janas, Renata Gieroba, Agnieszka Korga, Ewa Poleszak and Jaroslaw Dudka
DOI: 10.2174/1871527315666161010152414
The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex
Research Article
Differential Mechanisms Underlying Antidepressant Responses of Ketamine and Imipramine
, 16(7): 846 - 853Zhisheng Wei, Ke Zhang, Qinji Zhou, Mingfa Huang, Ting Xu, Jianyang Dong, Yu Zheng and Xiang Cai*
DOI: 10.2174/1871527316666170428123248
Differential Mechanisms Underlying Antidepressant Responses of Ketamine and Imipramine
Editor-in-Chief
Edoardo Spina
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria
Messina
(Italy)
Biography
Department of Clinical and Experimental Medicine
University of Messina
Policlinico Universitario
Via Consolare Valeria
Messina
Biography
Biography of Edoardo Spina
Dr. Spina graduated in Medicine, specialized in Neurology and in Psychiatry at the University of Messina, Italy. He obtained a doctorate (Ph.D) in Clinical Pharmacology at Karolinska Institute, Stockholm. Currently, Dr. Spina is Professor of Pharmacology at the Department of Clinical and Experimental Medicine, University of Messina. His main scientific interest is clinical neuropsychopharmacology. Dr. Spina authored more than 200 articles in international journals and 2 books. He is Associate Editor of Frontiers in Pharmacogenetics and member of the editorial board of Therapeutic Drug Monitoring, Basic & Clinical Pharmacology & Toxicology and Neuropsychiatric Disease and Treatment.
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Journal History
Current Drug Targets - CNS & Neurological Disorders was launched in 2002 and later renamed in 2006 as CNS & Neurological Disorders - Drug Targets.
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