Contents

CNS & Neurological Disorders - Drug Targets , Volume 16 - Number 7


Review Article

Recent Advances on the Role of Neurogenesis in the Adult Brain: Therapeutic Potential in Parkinson's and Alzheimer's Diseases

, 16(7): 740 - 748

Khaled Radad, Rudolf Moldzio, Mubarak Al-Shraim, Barbara Kranner, Christopher Krewenka and Wolf-Dieter Rausch


DOI: 10.2174/1871527316666170623094728



Review Article

The Role of Innate Immune System Receptors in Epilepsy Research

, 16(7): 749 - 762

Jessica Cordero-Arreola, Rachel M. West, Julieta Mendoza-Torreblanca, Edna Mendez-Hernandez, Jose Salas-Pacheco, Manuel Menendez-Gonzalez, Rafael C. Freire, Sergio Machado, Eric Murillo-Rodriguez, Antonio E. Nardi and Oscar Arias-Carrion


DOI: 10.2174/1871527316666170725145549



Review Article

Natural Steroids and Androgen Antagonists used as Neuroprotection in Common Neurological Disorders

, 16(7): 763 - 771

David Calderon Guzman, Hugo Juarez Olguin, Ernestina Hernandez Garcia, Monica Punzo Soto, Mayra Santillan Garcia and Gerardo Barragan Mejia


DOI: 10.2174/1871527316666170714121654



Research Article

Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats

, 16(7): 772 - 780

Carmen Rubio, Artemio Rosiles-Abonce, Cristina Trejo-Solis, Moises Rubio-Osornio, Cesar Mendoza, Veronica Custodio, Juan C Martinez-Lazcano, Edith Gonzalez and Carlos Paz


DOI: 10.2174/1871527316666170117114513



Research Article

Granulocyte Colony-Stimulating Factor Attenuates Blood-Brain Barrier Damage and Improves Cognitive Function in Spontaneously Hypertensive Rats

, 16(7): 781 - 788

Xin Wei, Yan Xu, Yanling Jin, Hongliang Feng, Yunyue Xiao and Shouquan Dong


DOI: 10.2174/1871527316666170207155730



Research Article

Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Metaanalysis of Randomized Controlled Trials

, 16(7): 789 - 799

Ahmed Elmaraezy, Abdelrahman Ibrahim Abushouk, Soha Saad, Moutaz Eltoomy, Osama Mahmoud, Hossam Mahmoud Hassan, Ahmed Aboelmakarem, Ahmed Aboel Fotoh, Farah Althaher, Nguyen Tien Huy and Kenji Hirayama


DOI: 10.2174/1871527315666161213110104



Research Article

Advanced Structure-activity Relationships Applied to Mentha spicata L. Subsp. spicata Essential Oil Compounds as AChE and NMDA Ligands, in Comparison with Donepezil, Galantamine and Memantine – New Approach in Brain Disorders Pharmacology

, 16(7): 800 - 811

Speranta Avram, Maria Mernea, Eyup Bagci, Lucian Hritcu, Livia-Cristina Borcan and Dan Florin Mihailescu


DOI: 10.2174/1871527316666170113115004



Research Article

Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome

, 16(7): 812 - 819

Sandra Guidi, Patrizia Bianchi, Fiorenza Stagni, Andrea Giacomini, Marco Emili, Stefania Trazzi, Elisabetta Ciani and Renata Bartesaghi


DOI: 10.2174/1871527315666160801143108



Research Article

Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses

, 16(7): 820 - 827

Mohammad A. Kamal, Shazi Shakil, Muhammad S. Nawaz, Qian-sheng Yu, David Tweedie, Y. Tan, Xianqin Qu and Nigel H. Greig


DOI: 10.2174/1871527316666170207160606



Research Article

Brain-derived Neurotrophic Factor Promotes Growth of Neurons and Neural Stem Cells Possibly by Triggering the Phosphoinositide 3-Kinase/ AKT/Glycogen Synthase Kinase-3β/β-catenin Pathway

, 16(7): 828 - 836

Xing-tong Li, Zhang Liang, Tong-tong Wang, Jin-wei Yang, Wei Ma, Shi-kang Deng, Xian-bin Wang, Yun-fei Dai, Jian-hui Guo and Li-yan Li


DOI: 10.2174/1871527316666170518170422



Research Article

The Positive Synergism of CPT and MK-801 in Behavioral Tests and in Reduction of Environmental Stress and Redox Signaling Changes in Mice Cerebral Cortex

, 16(7): 837 - 845

Mariola Herbet, Aleksandra Szopa, Sylwia Wosko, Anna Serefko, Magdalena Izdebska, Monika Gawronska-Grzywacz, Iwona Piatkowska-Chmiel, Martyna Janas, Renata Gieroba, Agnieszka Korga, Ewa Poleszak and Jaroslaw Dudka


DOI: 10.2174/1871527315666161010152414



Research Article

Differential Mechanisms Underlying Antidepressant Responses of Ketamine and Imipramine

, 16(7): 846 - 853

Zhisheng Wei, Ke Zhang, Qinji Zhou, Mingfa Huang, Ting Xu, Jianyang Dong, Yu Zheng and Xiang Cai


DOI: 10.2174/1871527316666170428123248




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