Contents

CNS & Neurological Disorders - Drug Targets , Volume 13 - Number 7

Conference Proceedings

Conference Report: 9th International Summer School of Neurology

, 13(7): 1121 - 1124

Stephen D. Skaper


DOI: 10.2174/187152731307141015103424




Editorial

Editorial (Thematic Issue: Linkage of Neurodegenerative Disorders with Other Health Issues – Volume I)

, 13(7): 1125 - 1129

Mohammad Amjad Kamal


DOI: 10.2174/1871527313666141002130423




Quinoline Derivatives: Candidate Drugs for a Class B G-Protein Coupled Receptor, the Calcitonin Gene-Related Peptide Receptor, a Cause of Migraines

, 13(7): 1130 - 1139

Hira Iftikhar, Iqra Ahmad, Siew H. Gan, Munvar M. Shaik, Naveed Iftikhar, Muhammad S. Nawaz, Nigel H. Greig and Mohammad A. Kamal


DOI: 10.2174/1871527313666140917111341




Link Between Chronic Bacterial Inflammation and Alzheimer Disease

, 13(7): 1140 - 1147

Fehmida Bibi, Muhammad Yasir, Sayed S. Sohrab, Esam I. Azhar, Mohammed H. Al-Qahtani, Adel M. Abuzenadah, Mohammad A. Kamal and Muhammad I. Naseer


DOI: 10.2174/1871527313666140917115741




Interaction of Different Proteins with GABAA Receptor and their Modulatory Effect on Inhibitory Neural Transmission Leads to Epilepsy

, 13(7): 1148 - 1159

Muhammad Faheem, Adeel G. Chaudhary, Taha A. Kumosani, Mohammad H. Al-Qahtani, Muhammad Yasir, Fehmida Bibi, Myeong O. Kim, Mahmood Rasool and Muhammad I. Naseer


DOI: 10.2174/1871527313666140917115121




The Impact of Dementia Development Concurrent with Parkinson's Disease: A New Perspective

, 13(7): 1160 - 1168

Alyce Russell, Alesya Drozdova, Wei Wang and Meghan Thomas


DOI: 10.2174/1871527313666140917122739




Computational Study of Human Tyrosine Hydroxylase Mutants to Uphold [4-(Propan-2-yl) Phenyl]Carbamic Acid as a Potential Inhibitor

, 13(7): 1169 - 1174

Muhammad S. Nawaz, Zahida Parveen, Liyong Wang, Sajid Rashid, Muhammad Q. Fatmi and Mohammad A. Kamal


DOI: 10.2174/1871527313666140917111905




Natural Compounds and Plant Extracts as Therapeutics Against Chronic Inflammation in Alzheimer's Disease - A Translational Perspective

, 13(7): 1175 - 1191

Nadine Apetz, Gerald Munch, Suresh Govindaraghavan and Erika Gyengesi


DOI: 10.2174/1871527313666140917110635




Biological Mechanisms Linking Alzheimer's Disease and Type-2 Diabetes Mellitus

, 13(7): 1192 - 1201

Gohar Mushtaq, Jalaluddin A. Khan and Mohammad A. Kamal


DOI: 10.2174/1871527313666140917114537




Transcriptomics Study of Neurodegenerative Disease: Emphasis on Synaptic Dysfunction Mechanism in Alzheimer's Disease

, 13(7): 1202 - 1212

Sajjad Karim, Zeenat Mirza, Shakeel A. Ansari, Mahmood Rasool, Zafar Iqbal, Sayed S. Sohrab, Mohammad A. Kamal, Adel M. Abuzenadah and Mohammed H. Al-Qahtani


DOI: 10.2174/1871527313666140917113446




The Role of Viruses in Neurodegenerative and Neurobehavioral Diseases

, 13(7): 1213 - 1223

Sajjad Karim, Zeenat Mirza, Mohammad A. Kamal, Adel M.Abuzenadah, Esam I. Azhar, Mohammed H. Al-Qahtani, Ghazi A. Damanhouri, Fahim Ahmad, Siew H. Gan and Sayed S. Sohrab


DOI: 10.2174/187152731307141015122638




Protein Interactions Between the C-Terminus of Aβ-Peptide and Phospholipase A2 - A Structure Biology Based Approach to Identify Novel Alzheimer's Therapeutics

, 13(7): 1224 - 1231

Zeenat Mirza, Vikram G. Pillai and Mohammad A. Kamal


DOI: 10.2174/1871527313666140917112248




Regulatory Cascade of Neuronal Loss and Glucose Metabolism

, 13(7): 1232 - 1245

Mubashir Hassan, Sheikh A. Sehgal and Sajid Rashid


DOI: 10.2174/1871527313666140917120444




Ignored Avenues in Alpha-Synuclein Associated Proteopathy

, 13(7): 1246 - 1257

Rimpy K. Chowhan, Shruti Mittal, Tanveer A. Dar, Mohammad A. Kamal and Laishram R. Singh


DOI: 10.2174/1871527313666140917121943




Aptiom (Eslicarbazepine Acetate) as a Dual Inhibitor of β-Secretase and Voltage-Gated Sodium Channel: Advancement in Alzheimer's Disease-Epilepsy Linkage via an Enzoinformatics Study

, 13(7): 1258 - 1262

Sibhghatulla Shaikh, Syed M.D. Rizvi, Nida Hameed, Deboshree Biswas, Mahiuddin Khan, Shazi Shakil and Mohammad A. Kamal


DOI: 10.2174/1871527313666140917121600




Expression and Secretion of Wild Type and Mutant GNE Proteins in Dictyostelium discoideum

, 13(7): 1263 - 1272

Sonam Grover, Saima Aslam, Vijeta Sharma and Ranjana Arya


DOI: 10.2174/1871527313666140917094905




New Targets for Treating the Underlying Pathophysiology and Nonmotor Aspects of Parkinson's Disease

, 13(7): 1273 - 1279

Jonathan T. Butler and Christopher Tolleson


DOI: 10.2174/1871527313666140917104850




Protein Misfolding and Aggregation in Alzheimer's Disease and Type 2 Diabetes Mellitus

, 13(7): 1280 - 1293

Ghulam M. Ashraf, Nigel H. Greig, Taqi A. Khan, Iftekhar Hassan, Shams Tabrez, Shazi Shakil, Ishfaq A. Sheikh, Syed K. Zaidi, Mohammad Akram, Nasimudeen R. Jabir, Chelaprom K. Firoz, Aabgeena Naeem, Ibrahim M. Alhazza, Ghazi A. Damanhouri and Mohammad A. Kamal


DOI: 10.2174/1871527313666140917095514




Cholinergic System Dysfunction and Neurodegenerative Diseases: Cause or Effect?

, 13(7): 1294 - 1303

Ada M. Tata, Lucia Velluto, Chiara D'Angelo and Marcella Reale


DOI: 10.2174/1871527313666140917121132




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