Contents

CNS & Neurological Disorders - Drug Targets , Volume 13 - Number 4

Conference Proceedings

Conference Report: The American Association for the Advancement of Science (AAAS), 180th Annual Meeting Chicago, IL, USA Feb 13-17, 2014 “Meeting Global Challenges: Discoveries & Innovation”

, 13(4): 553 - 555

Hari S. Sharma and Aruna Sharma


DOI: 10.2174/187152731304140702104643




Commentary

Commentary (Research Highlights: Wnt-Signalling: A New Direction for Alzheimer Disease?)

, 13(4): 556

Stephen D. Skaper


DOI: 10.2174/187152731304140702104826




Editorial

Editorial (Thematic Issue: Molecular Targeting for Development of Novel Therapeutic Strategies in Brain Diseases: Myth or Reality?)

, 13(4): 557

Jean F. Soustiel


DOI: 10.2174/18715273113126660201




Positive Allosteric Modulators (PAMs) of Metabotropic Glutamate Receptor 5 (mGluR5) Attenuate Microglial Activation

, 13(4): 558 - 566

Fengtian Xue, Bogdan A. Stoica, Marie Hanscom, Shruti V. Kabadi and Alan I. Faden


DOI: 10.2174/18715273113126660199




Novel Approach to the Role of NMDA Receptors in Traumatic Brain Injury

, 13(4): 567 - 573

Esther Shohami and Anat Biegon


DOI: 10.2174/18715273113126660196




Concentration-Dependent Bimodal Effect of Specific 18 kDa Translocator Protein (TSPO) Ligands on Cell Death Processes Induced by Ammonium Chloride: Potential Implications for Neuropathological Effects Due to Hyperammonemia

, 13(4): 574 - 592

Beatriz Caballero, Leo Veenman, Julia Bode, Svetlana Leschiner and Moshe Gavish


DOI: 10.2174/18715273113126660194




Subcellular Injuries in Alzheimer's Disease

, 13(4): 593 - 605

Jean-Paul Tillement and Vassilios Papadopoulos


DOI: 10.2174/18715273113126660197




Mitochondrial Neuroprotection in Traumatic Brain Injury: Rationale and Therapeutic Strategies

, 13(4): 606 - 619

Shoji Yokobori, Anna T. Mazzeo, Shyam Gajavelli and Malcolm R. Bullock


DOI: 10.2174/187152731304140702112805




Involvement of the Mitochondrial Benzodiazepine Receptor in Traumatic Brain Injury: Therapeutic Implications

, 13(4): 620 - 629

Eugene Vlodavsky, Eilam Palzur and Jean F. Soustiel


DOI: 10.2174/187152731304140702114630




α-Synuclein Ubiquitination and Novel Therapeutic Targets for Parkinson's Disease

, 13(4): 630 - 637

Ruth Rott, Raymonde Szargel, Vered Shani, Sleman Bisharat and Simone Engelender


DOI: 10.2174/18715273113126660195




Citrus Peel Extract Attenuates Acute Cyanide Poisoning-Induced Seizures and Oxidative Stress in Rats

, 13(4): 638 - 646

Ahmed E. Abdel Moneim


DOI: 10.2174/1871527312666131206095142




Effect of Glatiramer Acetate on Peripheral Blood Brain-Derived Neurotrophic Factor and Phosphorylated TrkB Levels in Relapsing- Remitting Multiple Sclerosis

, 13(4): 647 - 651

Vitalie Vacaras, Zsigmond Z. Major, Dafin F. Muresanu, Tibor L. Krausz, Ioan Marginean and Dana A. Buzoianu


DOI: 10.2174/1871527313666140618110049




Significant Overlapping Modules and Biological Processes Between Stroke and Coronary Heart Disease

, 13(4): 652 - 660

Yingying Zhang, Pengyun Kong, Yinying Chen, Yanan Yu, Jun Liu, Liqiang Yang, Tao Zhao, Jingyi Nan and Zhong Wang


DOI: 10.2174/1871527312666131223115112




Effects of Brain IKKβ Gene Silencing by Small Interfering RNA on P-Glycoprotein Expression and Brain Damage in the Rat Kainic Acid-Induced Seizure Model

, 13(4): 661 - 672

Nian Yu, Hao Liu, Yan-Fang Zhang, Ling-Ying Su, Xin-Hong Liu, Le-Chao Li, Jin-Bo Hao, Xian-Jing Huang and Qing Di


DOI: 10.2174/18715273113129990106




Scopolamine and Depression: A Role for Muscarinic Antagonism?

, 13(4): 673 - 683

Helge Hasselmann


DOI: 10.2174/1871527313666140618105710




Neuroprotective Effects of Citrus reticulata in Scopolamine-Induced Dementia Oxidative Stress in Rats

, 13(4): 684 - 690

Manal F. El-Khadragy, Ebtesam M. Al-Olayan and Ahmed E. Abdel Moneim


DOI: 10.2174/1871527313666140618105404




Crystal Structure and Interaction of Phycocyanin with β-Secretase: A Putative Therapy for Alzheimer's Disease

, 13(4): 691 - 698

Niraj Kumar Singh, Syed S. Hasan, Jitendra Kumar, Isha Raj, Amrin A. Pathan, Asha Parmar, Shazi Shakil, Samudrala Gourinath and Datta Madamwar


DOI: 10.2174/1871527313666140228114456




Computational Analysis of TRAPPC9: Candidate Gene for Autosomal Recessive Non-Syndromic Mental Retardation

, 13(4): 699 - 711

Naureen Aslam Khattak and Asif Mir


DOI: 10.2174/18715273113129990105




Cerebrovascular Profile Assessment in Parkinson's Disease Patients

, 13(4): 712 - 717

Laura Perju-Dumbrava, Maria-Lucia Muntean and Dafin Fior Muresanu


DOI: 10.2174/1871527313666140618110409




Inhibition of Brain Ischemia-Caused Notch Activation in Microglia May Contribute to Isoflurane Postconditioning-Induced Neuroprotection in Male Rats

, 13(4): 718 - 732

Jinbo Yin, Hong Li, Chenzhuo Feng and Zhiyi Zuo


DOI: 10.2174/1871527313666140618110837




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