Contents

CNS & Neurological Disorders - Drug Targets , Volume 12 - Number 8

Commentary

Commentary: Olfactory Dysfunction in Parkinson’s Disease

, 12(8): 1079 - 1080

Jiang Li, Ying Cui, Ti-Fei Yuan and Oscar Arias-Carrion


DOI: 10.2174/1871527312999131230144317




Commentary: Multifactoriality of Amytrophic Lateral Sclerosis: Linking Unfolded Proteins to Oxidative Stress in Microglia

, 12(8): 1081 - 1082

Nadia D’Ambrosi and Cinzia Volonte


DOI: 10.2174/18715273113129990113




Editorial (Thematic Issue: Novel Perspectives for Parkinson’s Disease Therapy: Insights from the Latest Advances in Disease Pathophysiology, Diagnostic and Experimental Tools and Molecular Targets)

, 12(8): 1083 - 1085

Pier Franco Spano and Arianna Bellucci


DOI: 10.2174/187152731131200129




Overlapping Molecular Signatures in Parkinson's Patient Leukocytes Before and After Treatment and in Mouse Model Brain Regions

, 12(8): 1086 - 1093

Lilach Soreq, Hagai Bergman, Zvi Israel and Hermona Soreq


DOI: 10.2174/187152731131200119




Synaptic Dysfunction in Synucleinopathies

, 12(8): 1094 - 1100

Oleg Anichtchik, Laura Calo and Maria Grazia Spillantini


DOI: 10.2174/18715273113129990114




Receptor Heteromers in Parkinson’s Disease and L-DOPA-Induced Dyskinesia

, 12(8): 1101 - 1113

Chiara Fiorentini, Paola Savoia, Daria Savoldi and Cristina Missale


DOI: 10.2174/187152731131200118




Induced Pluripotent Stem Cell-Based Studies of Parkinson's Disease: Challenges and Promises

, 12(8): 1114 - 1127

Adriana Sanchez-Danes, Patrizia Benzoni, Maurizio Memo, Patrizia Dell’Era, Angel Raya and Antonella Consiglio


DOI: 10.2174/187152731131200128




Targeting Striatal Metabotropic Glutamate Receptor Type 5 in Parkinson’s Disease: Bridging Molecular Studies and Clinical Trials

, 12(8): 1128 - 1142

A. Vallano, V. Fernandez-Duenas, G. Garcia-Negredo, M.A. Quijada, C.P. Simon, M.L. Cuffí, L. Carbonell, S. Sanchez, J.M. Arnau and F. Ciruela


DOI: 10.2174/18715273113129990115




Editorial

Editorial: Steroid-Dependent Management of Biological Responses in the Nervous System

, 12(8): 1143 - 1145

Mario D. Galigniana


DOI: 10.2174/187152731131200127




Pathogenic Mechanisms and Therapeutic Strategies in Spinobulbar Muscular Atrophy

, 12(8): 1146 - 1156

Jason P. Chua and Andrew P. Lieberman


DOI: 10.2174/187152731131200124




The Role of FKBP5 in Mood Disorders: Action of FKBP5 on Steroid Hormone Receptors Leads to Questions About its Evolutionary Importance

, 12(8): 1157 - 1162

John C. O’Leary III, Bo Zhang, John Koren III, Laura Blair and Chad A. Dickey


DOI: 10.2174/187152731131200121




Molecular Basis of Mineralocorticoid Receptor Action in the Nervous System

, 12(8): 1163 - 1174

Alejandro M. Molinari, Mayra Y. Machado-Rada, Gisela I. Mazaira, Alejandra G. Erlejman and Mario D. Galigniana


DOI: 10.2174/187152731131200122




Contribution of Glucocorticoids and Glucocorticoid Receptors to the Regulation of Neurodegenerative Processes

, 12(8): 1175 - 1193

Sheela Vyas and Layal Maatouk


DOI: 10.2174/187152731131200125




Comparison of Glucocorticoid Receptor- and Epigenetically Regulated Genes in Proliferating Versus Growth-Arrested Neuro-2a Cells

, 12(8): 1194 - 1204

Jurgen Zschocke, Peter Weber, Nicole Zimmermann and Theo Rein


DOI: 10.2174/187152731131200126




Therapeutic Effects of Progesterone in Animal Models of Neurological Disorders

, 12(8): 1205 - 1218

Alejandro F. De Nicola, Florencia Coronel, Laura I. Garay, Gisella Gargiulo-Monachelli, Maria Claudia Gonzalez Deniselle, Susana L. Gonzalez, Florencia Labombarda, Maria Meyer, Rachida Guennoun and Michael Schumacher


DOI: 10.2174/187152731131200120




Neuroprotective Effects of Non-Classical Estrogen-Like Signaling Activators: from Mechanism to Potential Implications

, 12(8): 1219 - 1225

Andrea Kwakowsky, Zsombor Koszegi, Rachel Y. Cheong and Istvan M. Abraham


DOI: 10.2174/187152731131200123




Chronic Paroxetine Treatment: Effects on Other Non-Serotonergic Neurotransmitter Systems

, 12(8): 1226 - 1232

Paola Ballesteros-Zebadua, Joaquin Manjarrez-Marmolejo and Javier Franco-Perez


DOI: 10.2174/18715273113126660182




Serum Cytokine Profile in Alzheimer's Disease Patients After Ingestion of an Antioxidant Beverage

, 12(8): 1233 - 1241

J.M. Rubio-Perez and J.M. Morillas-Ruiz


DOI: 10.2174/18715273113129990075




Exploring the Role of Nerve Growth Factor in Multiple Sclerosis: Implications in Myelin Repair

, 12(8): 1242 - 1256

C.M.R. Acosta, C. Cortes, H. MacPhee and M.P. Namaka


DOI: 10.2174/18715273113129990087




Beyond Rodent Models of Pain: Non-Human Primate Models for Evaluating Novel Analgesic Therapeutics and Elaborating Pain Mechanisms

, 12(8): 1257 - 1270

Aldric T. Hama, Katsuo Toide and Hiroyuki Takamatsu


DOI: 10.2174/18715273113129990111




Highly Organized Nanostructures for Brain Drug Delivery - New Hope or Just a Fad?

, 12(8): 1271 - 1285

K. Labuzek, K. Gorki, H. Jaroszek, K. Jarzabek, B. Gabryel and B. Okopien


DOI: 10.2174/18715273113129990109




Acknowledgements to Reviewers:

, 12(8): 1286


DOI: 10.2174/187152731208140102225512




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