Contents

CNS & Neurological Disorders - Drug Targets , Volume 12 - Number 6

Conference Report:

, 12(6): 715 - 716

Stephen D. Skaper


DOI: 10.2174/1871527311312060001




Commentary: (Research Highlights: “MiRNAcles” in Brain)

, 12(6): 717 - 718

Chiara Parisi and Cinzia Volonté


DOI: 10.2174/18715273113126660180




Editorial

Editorial (Thematic Issue: Microglia - A Therapeutic Target in Neurological Diseases and Disorders)

, 12(6): 719

Charanjit Kaur and Eng-Ang Ling


DOI: 10.2174/18715273113126660179




Role of Microglia in the Pathogenesis of Sepsis-Associated Encephalopathy

, 12(6): 720 - 725

Y.Y. Deng, M. Fang, G.F. Zhu, Y. Zhou and H.K. Zeng


DOI: 10.2174/18715273113126660178




A Friend in Need May Not be a Friend Indeed: Role of Microglia in Neurodegenerative Diseases

, 12(6): 726 - 740

Deepak Kumar Kaushik and Anirban Basu


DOI: 10.2174/18715273113126660170




Screening for Inhibitors of Microglia to Reduce Neuroinflammation

, 12(6): 741 - 749

Shazia Samanani, Manoj Mishra, Claudia Silva, Brooke Verhaeghe, Janet Wang, Jade Tong and V. Wee Yong


DOI: 10.2174/18715273113126660177




The Potential for Genetically Altered Microglia to Influence Glioma Treatment

, 12(6): 750 - 762

W. Li, R.M.D. Holsinger, C.A. Kruse, A. Flügel and M.B. Graeber


DOI: 10.2174/18715273113126660171




Microglial Senescence

, 12(6): 763 - 767

Wolfgang J. Streit and Qing-Shan Xue


DOI: 10.2174/18715273113126660176




Microglia and Neuropathic Pain

, 12(6): 768 - 772

Håkan Aldskogius and Elena N. Kozlova


DOI: 10.2174/18715273113126660168




Glutamate Receptors in Microglia

, 12(6): 773 - 784

Madhuvika Murugan, Eng-Ang Ling and Charanjit Kaur


DOI: 10.2174/18715273113126660174




Consequences of Iron Accumulation in Microglia and its Implications in Neuropathological Conditions

, 12(6): 785 - 798

Gurugirijha Rathnasamy, Eng-Ang Ling and Charanjit Kaur


DOI: 10.2174/18715273113126660169




Potential Drugs Targeting Microglia: Current Knowledge and Future Prospects

, 12(6): 799 - 806

Parakalan Rangarajan, Ling Eng-Ang and S. Thameem Dheen


DOI: 10.2174/18715273113126660175




Notch Signaling in the Central Nervous System with Special Reference to its Expression in Microglia

, 12(6): 807 - 814

Linli Yao, Qiong Cao, Chunyun Wu, Charanjit Kaur, Aijun Hao and Eng-Ang Ling


DOI: 10.2174/18715273113126660172




Relationship Between the Chemokine Receptor CCR5 and Microglia in Neurological Disorders: Consequences of Targeting CCR5 on Neuroinflammation, Neuronal Death and Regeneration in a Model of Epilepsy

, 12(6): 815 - 829

Jean-Pierre Louboutin and David S. Strayer


DOI: 10.2174/18715273113126660173




The Neuroprotective Effects of Purslane (Portulaca oleracea) on Rotenone- Induced Biochemical Changes and Apoptosis in Brain of Rat

, 12(6): 830 - 841

Ahmed E. Abdel Moneim


DOI: 10.2174/18715273113129990081




Interplay Between Cholesterol and Homocysteine in the Exacerbation of Amyloid-β Toxicity in Human Neuroblastoma Cells

, 12(6): 842 - 848

Aydé Mendoza-Oliva, Patricia Ferrera and Clorinda Arias


DOI: 10.2174/18715273113129990083




Alteration of Isocitrate Dehydrogenase Following Acute Ischemic Injury as a Means to Improve Cellular Energetic Status in Neuroadaptation

, 12(6): 849 - 860

Kimberly N. Grelli, Amy M. Palubinsky, A. Cozette Kale, Britney N. Lizama-Manibusan, Jeannette N. Stankowski, Ginger L. Milne, Robert Singer and BethAnn McLaughlin


DOI: 10.2174/18715273113129990062




Improving the Treatment of Schizophrenia: Role of 5-HT Receptors in Modulating Cognitive and Extrapyramidal Motor Functions

, 12(6): 861 - 869

Saki Shimizu, Yuto Mizuguchi and Yukihiro Ohno


DOI: 10.2174/18715273113129990088




Vascular Oxidative Stress and Mitochondrial Failure in the Pathobiology of Alzheimer’s Disease: A New Approach to Therapy

, 12(6): 870 - 881

Marta Sochocka, Euphrosyni S. Koutsouraki, Kazimierz Gasiorowski and Jerzy Leszek


DOI: 10.2174/18715273113129990072




Hierarchical Profiles of Signaling Pathways and Networks Reveal Two Complementary Pharmacological Mechanisms

, 12(6): 882 - 893

Yinying Chen, Fanyun Meng, Hong Fang, Yanan Yu, Jun Liu, Zhiwei Jing, Aiping Lv, Zhong Wang and Yongyan Wang


DOI: 10.2174/18715273113129990073




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