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Cardiovascular & Hematological Disorders-Drug Targets

Formerly: Current Drug Targets - Cardiovascular & Hematological Disorders

Volume 19, 3 Issues, 2019
ISSN: 2212-4063 (Online)
ISSN: 1871-529X (Print)
This journal supports open access

Aims & Scope

Cardiovascular & Hematological Disorders-Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in cardiovascular and hematological disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of in-depth/mini reviews, original research articles, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cardiovascular and hematological disorders. As the discovery, identification, characterization and validation of novel human drug targets for cardiovascular and hematological drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Cardiovascular & Hematological Disorders-Drug Targets

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Volume 19

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Number 2



Biography   Open Access



Perspective in Cardiovascular and Haematological Disorders-Drug Targets   Open Access



Review Article



Review Article

Adenosine as a Marker and Mediator of Cardiovascular Homeostasis: A Translational Perspective

, 19(2): 109 - 131

Trevor Simard, Richard Jung, Alisha Labinaz, Mohammad Ali Faraz, F. Daniel Ramirez, Pietro Di Santo, Ian Pitcher, Pouya Motazedian, Chantal Gaudet, Rebecca Rochman, Jeffrey Marbach, Paul Boland, Kiran Sarathy, Saleh Alghofaili, Juan J. Russo, Etienne Couture, Rob S. Beanlands and Benjamin Hibbert*


DOI: 10.2174/1871529X18666181011103719


Review Article



Review Article



Research Article

The Effect of Borage (Echium amoenum) on the Mouse Heart and Hematology Parameters

, 19(2): 154 - 159

Parisa Sadighara*, Atefeh Araghi, Behrouz Tajdar-oranj, Leila Peivasteh Roudsari, Afsaneh Mohajer and Ramezan Behzadi


DOI: 10.2174/1871529X18666181105113617


Research Article



Articles Ahead of Print

CD123: A Novel Biomarker for Diagnosis and Treatment of Leukemia


Mingyue Shi, Ruijun Jeanna Su, Kamal-Preet Parmar, Rahman Chaudhry, Kai Sun, Jianyu Rao and Mingyi Chen*


DOI: 10.2174/1871529X19666190627100613
View Abstract View on PubMed



P Wave Dispersion and Silent Atrial Fibrillation in Cryptogenic Stroke: The Pathogenic Role of Inflammation


Maurizio Acampa*, Pietro Enea Lazzerini, Francesca Guideri, Rossana Tassi, Alessandra Cartocci and Giuseppe Martini


DOI: 10.2174/1871529X19666190410145501
View Abstract View on PubMed



An HHV-8 Positive HIV Negative Multicentric Castleman’s Disease, who Responded well to Rituximab Alone


Dimitris Kounatidis, Dimitra Rontogianni, Dimitrios Sampaziotis, Maria Vardaka, Chara Giatra, Christodoulos Dolapsakis, Evangelia Margellou and Natalia G. Vallianou*


DOI: 10.2174/1871529X19666190227185318
View Abstract View on PubMed



Impact of the Fontan Operation on Organ Systems


Miriam Michel*, Manuela Zlamy, Andreas Entenmann, Karin Pichler, Sabine Scholl-Bürgi, Daniela Karall, Ralf Geiger, Christina Salvador, Christian Niederwanger and Hideo Ohuchi


DOI: 10.2174/1871529X19666190211165124
View Abstract View on PubMed



Relationship Between Single-Nucleotide Polymorphisms of Tumor Necrosis Factor Alpha, Interleukin-10, Factor II and Factor V with Risk of Inhibitor Development in Patients with Severe Hemophilia A


Shahrzad Souri, Ghazaleh Dadashizadeh, Akbar Dorgalaleh, Shadi Tabibian, Mohammad Reza Keramati, Shaban Alizadeh, Maryam Sadat Hosseini, Farhad Zaker* and Mahmood Shams


DOI: 10.2174/1871529X19666190206152315
View Abstract View on PubMed


Genetics of Atrial Fibrilation: In Search of Novel Therapeutic Targets


Estefanía Lozano-Velasco, Carlos Garcia-Padilla, Amelia E. Aránega and Diego Franco*


DOI: 10.2174/1871529X19666190206150349
View Abstract View on PubMed


Published Contents

Editor's Choice

Comprehensive Review on Diabetes Associated Cardiovascular Complications - The Vitamin D Perspective

, 2019; 19(2): 139 - 153

Y. Durgarao, Poornima A. Manjrekar*, Prabha Adhikari, M. Chakrapani and M.S. Rukmini


DOI: 10.2174/1871529X19666190114155302



Role of AMPK in Diabetic Cardiovascular Complications: An Overview

, 2019; 19(1): 5 - 13

Karthika Nellaiappan, Veera Ganesh Yerra and Ashutosh Kumar*


DOI: 10.2174/1871529X18666180508104929




Sodium-glucose Cotransporter 2 Inhibitors: Nephroprotective Impact on Diabetic Kidney Disease

, 2018; 18(2): 120 - 126

Konstantinos Stavropoulos*, Konstantinos P. Imprialos, Nikiforos Stavropoulos, Sofia Bouloukou, Georgios Kerpiniotis, Kyriakos Dimitriadis, Constantinos Tsioufis and Michael Doumas


DOI: 10.2174/1871529X18666180206155349




Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation

, 2017; 17(3): 195 - 204

Mohammad Al-Ani, Sriram Ambadapadi, Jordan R. Yaron, Donghang Zheng, Adisson Fortunel, Maia Doroton-Guevara, Liying Liu, Sufi Morshed, Jay Fricker, William Miles, Matthew McKillop and Alexandra Lucas*


DOI: 10.2174/1871529X17666170918140442






Neuroinflammation in Sepsis: Sepsis Associated Delirium

, 2015; 15(1): 10 - 18

Simone Piva, Victoria A. McCreadie and Nicola Latronico


DOI: 10.2174/1871529X15666150108112452



Open Access Articles

Relationship Between Level of Heart Type Fatty Acid Binding Protein (Before and after Procedures) with Acute Renal Failure after PCI in Patients Under PCI

, 2019; 19: 1 - 6 (E-Pub Ahead of Print)

Mina Mohammadzadeh, Habib Haybar*, Ahmad Reza Assare, Zeinab Deris Zayeri and Shahla Assadi Hoveyzian




Glucose Lowering Activity of Aqueous Ammodaucus leucotrichus Extract in Diabetic Rats

, 2019; 19: 1 - 8 (E-Pub Ahead of Print)

Fadwa El-ouady and Mohamed Eddouks*




An HHV-8 Positive HIV Negative Multicentric Castleman’s Disease, who Responded well to Rituximab Alone

, 2019; 19: 1 - 3 (E-Pub Ahead of Print)

Dimitris Kounatidis, Dimitra Rontogianni, Dimitrios Sampaziotis, Maria Vardaka, Chara Giatra, Christodoulos Dolapsakis, Evangelia Margellou and Natalia G. Vallianou*




P Wave Dispersion and Silent Atrial Fibrillation in Cryptogenic Stroke: The Pathogenic Role of Inflammation

, 2019; 19: 1 - 4 (E-Pub Ahead of Print)

Maurizio Acampa*, Pietro Enea Lazzerini, Francesca Guideri, Rossana Tassi, Alessandra Cartocci and Giuseppe Martini








Neuroinflammation in Sepsis: Sepsis Associated Delirium

, 2015; 15(1): 10 - 18

Simone Piva, Victoria A. McCreadie and Nicola Latronico







Most Cited Articles

Review Article

Nanoparticle based treatment for cardiovascular diseases

, 2019; 19(1): 33-44.

Purnima Gupta, Evelyn Garcia, Amrita Sarkar, Sumit Kapoor, Khadija Rafiq, Hitendra S. Chand and Rahul Dev Jayant*


DOI: 10.2174/1871529X18666180508113253



Review Article

Sodium-glucose cotransporter 2 inhibitors: Glucose lowering against other hypoglycemic agents

, 2018; 18(2): 94-103.

Konstantinos Avranas*, Konstantinos Imprialos, Konstantinos Stavropoulos, Georgios Lales, Alexandos Manafis, Anastasia Skalkou and Lars Kihm


DOI: 10.2174/1871529X18666180206160838


Review Article

Sodium-glucose cotransporter 2 inhibitors and the risk of diabetic ketoacidosis; from pathophysiology to clinical practice

, 2018; 18(2): 139-146.

Dimitrios Patoulias*, Alexandros Manafis, Christos Mitas, Konstantinos Avranas, Georgios Lales, Ioanna Zografou, Christos Sambanis and Asterios Karagiannis


DOI: 10.2174/1871529X18666180206123149


Review Article

Sodium-glucose cotransporter 2 inhibitors: Nephroprotective impact on diabetic kidney disease

, 2018; 18(2): 120-126.

Konstantinos Stavropoulos*, Konstantinos P. Imprialos, Nikiforos Stavropoulos, Sofia Bouloukou, Georgios Kerpiniotis, Kyriakos Dimitriadis, Constantinos Tsioufis and Michael Doumas


DOI: 10.2174/1871529X18666180206155349


General Review Article

Platelet activation polymorphisms in ischemia

, 2018; 18(2): 153-161.

Habib Haybar, Elahe Khodadi, Kazem Zibara and Najmaldin Saki*


DOI: 10.2174/1871529X18666180326121239


Review Article

Sodium-glucose cotransporter 2 inhibitors: Impact on body weight and blood pressure compared with other antidiabetic drugs

, 2018; 18(2): 104-113.

Konstantinos P. Imprialos*, Konstantinos Stavropoulos, Nikiforos Stavropoulos, Dimitrios Patoulias, Konstantinos Petidis, Charalampos Grassos, Kyriakos Dimitriadis and Constantinos Tsioufis


DOI: 10.2174/1871529X18666180206144342


Review Article

Immunomodulatory and anti-inflammatory effects of thymoquinone

, 2018; 18(1): 52-60.

Hanieh Shaterzadeh-Yazdi, Mohammad-Foad Noorbakhsh, Farzad Hayati, Saeed Samarghandian* and Tahereh Farkhondeh


DOI: 10.2174/1871529X18666180212114816



General Review Article

What genetics tells us about cardiovascular disease in diabetic patients?

, 2018; 18(2): 147-152.

Habib Haybar, Mohammad Taha Jalali and Zeinab Deris Zayeri*


DOI: 10.2174/1871529X18666180212114305


Review Article

Sodium-glucose cotransporter 2 inhibitors: The pleiotropic mechanisms of actions

, 2018; 18(2): 86-93.

Panteleimon Pantelidis*, Andreas Kalliakmanis, Christos Mitas, Michail Sideris, Charalampos Grassos, Andreas Pittaras and Athanasios Manolis


DOI: 10.2174/1871529X18666180206130218


Review Article

Sodium-glucose cotransporter 2 inhibitors: Potential cardiovascular and mortality benefits

, 2018; 18(2): 114-119.

Dragan Lovic*, Andreas Pittaras, Manolis Kallistratos, Constantinos Tsioufis, Charalampos Grassos, Dragan Djordjevic, Ivan Tasic and Athanasios Manolis


DOI: 10.2174/1871529X18666180227102137


Review Article

Sodium-glucose cotransporter 2 inhibitors and ischemic stroke

, 2018; 18(2): 134-138.

Dimitrios Milonas and Konstantinos Tziomalos*


DOI: 10.2174/1871529X18666180206120444


Review Article

Recent advances in understanding the pathogenesis of cardiovascular diseases and development of treatment modalities

, 2019; 19(1): 19-32.

Rahul Mittal*, Vasanti M. Jhaveri, Sae-In Samantha Kay, Aubrey Greer, Kyle J. Sutherland, Hannah S. McMurry , Nicole Lin, Jeenu Mittal, Arul K. Malhotra and Amit P. Patel


DOI: 10.2174/1871529X18666180508111353


Research Article

Pseudomonas aeruginosa invades human aortic endothelial cells and induces cell damage in vitro

, 2019; 19(1): 45-50.

Rahul Mittal*, Vasanti M. Jhaveri, Sae-In Samantha Kay, Patricia Blackwelder and Kunal Patel


DOI: 10.2174/1871529X18666180611094928



Most Accessed Articles


Nanoparticle Based Treatment for Cardiovascular Diseases

, 2019; 19(1): 33-44.

Purnima Gupta, Evelyn Garcia, Amrita Sarkar, Sumit Kapoor, Khadija Rafiq, Hitendra S. Chand and Rahul Dev Jayant*


DOI: 10.2174/1871529X18666180508113253



Role of AMPK in Diabetic Cardiovascular Complications: An Overview

, 2019; 19(1): 5-13.

Karthika Nellaiappan, Veera Ganesh Yerra and Ashutosh Kumar*


DOI: 10.2174/1871529X18666180508104929


Recent Advances in Understanding the Pathogenesis of Cardiovascular Diseases and Development of Treatment Modalities

, 2019; 19(1): 19-32.

Rahul Mittal*, Vasanti M. Jhaveri, Sae-In Samantha Kay, Aubrey Greer, Kyle J. Sutherland, Hannah S. McMurry , Nicole Lin, Jeenu Mittal, Arul K. Malhotra and Amit P. Patel


DOI: 10.2174/1871529X18666180508111353


Pseudomonas aeruginosa Invades Human Aortic Endothelial Cells and Induces Cell Damage in vitro

, 2019; 19(1): 45-50.

Rahul Mittal*, Vasanti M. Jhaveri, Sae-In Samantha Kay, Patricia Blackwelder and Kunal Patel


DOI: 10.2174/1871529X18666180611094928





Editor-in-Chief

Garry X. Shen
University of Manitoba
Winnipeg, MB
Canada

Biography View Full Editorial Board

Journal History

Cardiovascular and Hematological Disorders-drug Targets was launched in 2001. Dr. Garry X. Shen serves as the Editor-in-Chief of the journal.
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