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Cardiovascular & Hematological Disorders-Drug Targets

Formerly: Current Drug Targets - Cardiovascular & Hematological Disorders

Volume 20, 4 Issues, 2020
ISSN: 2212-4063 (Online)
ISSN: 1871-529X (Print)
This journal supports open access

Aims & Scope

Cardiovascular & Hematological Disorders-Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in cardiovascular and hematological disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of in-depth/mini reviews, original research articles, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cardiovascular and hematological disorders. As the discovery, identification, characterization and validation of novel human drug targets for cardiovascular and hematological drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Cardiovascular & Hematological Disorders-Drug Targets

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Volume 20

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Number 1



Biography   Open Access



Preface   Open Access



Systematic Review Article   Open Access

Bivalirudin Versus Heparin During Intervention in Acute Coronary Syndrome: A Systematic Review of Randomized Trials

, 20(1): 3 - 15

Sukhdeep Bhogal, Debabrata Mukherjee, Jayant Bagai, Huu T. Truong, Hemang B. Panchal, Ghulam Murtaza, Mustafa Zaman, Rajesh Sachdeva and Timir K. Paul*


DOI: 10.2174/1871529X19666190626124057


Research Article   Open Access



Research Article



Research Article   Open Access



Research Article   Open Access



Research Article



Articles Ahead of Print

Assessment of Admission Time Cell Blood Count (CBC) Parameters in Predicting Post-primary Percutaneous Coronary Intervention TIMI Frame Count in Patients with ST-segment Elevation Myocardial Infarction


Hossein Vakili, Isa Khaheshi*, Amirsina Sharifi, Negin Nickdoost, Mohammad Hasan Namazi, Morteza Safi , Habibollah Saadat, Saeed Alipour Parsa, Mohammad Ali Akbarzadeh, Mohammadreza Naderian, Negin Yousefi, Mahin Shirazi and Mohammadreza Tabary


DOI: 10.2174/1871529X20666200206123118
View Abstract View on PubMed


Co-existence of Follicular Lymphoma in the Lymph Node with High-grade B Cell Lymphoma in the Bone Marrow of a Patient with Spontaneous Tumor Lysis Syndrome


Chara Giatra, Alexandros G. Sykaras, Fotis Constantinou, Victoria Gennimata, Dimitrios Sampaziotis, Eleni Geladari, Dimitris Kounatidis and Natalia G. Vallianou*


DOI: 10.2174/1871529X20666200130095417
View Abstract View on PubMed



Efficacy of Cangrelor as Bridging Therapy Post PCI


Abdul Khan, Ghulam Murtaza*, Muhmammad Khalid, Mathew Finniss and Thomas Helton


DOI: 10.2174/1871529X20666200228114925
View Abstract View on PubMed


‘Do not Do’ Recommendations in Hemophilia


Hortensia De la Corte-Rodriguez, E. Carlos Rodriguez-Merchan*, Teresa Alvarez-Roman, Monica Martin-Salces and Victor Jimenez-Yuste


DOI: 10.2174/1871529X20666200305111323
View Abstract View on PubMed




Ethyl Acetate and Aqueous Fractions of Ziziphus Jujuba Prevent Acute Hypertension Induced by Angiotensin II in Rats


Yasamin Kamkar-Del, Reza Mohebbati, Mahmoud Hoseini, Abolfazl Khajavi Rad, Mohammad Naser Shafei* and Hassan Rakhshandeh


DOI: 10.2174/1871529X19666191119141400
View Abstract View on PubMed


Coexistence of Hodgkin and Non-Hodgkin Lymphoma; Composite Lymphoma [CL] in a Patient Presenting with Waxing and Waning Lymphadenopathy


Eleni Geladari, Georgia Dimopoulou, Evangelia Margellou, Andreas Paraskevas, Georgios Kafetzis, Dimitra Rontogianni and Maria Vadiaka*


DOI: 10.2174/1871529X19666191014111118
View Abstract View on PubMed


Effect of Curcumin on Serum Cathepsin D in Patients with Metabolic Syndrome


Leila Shirmohammadi, Majid Ghayour-Mobarhan*, Maryam Saberi-Karimian, Mehrdad Iranshahi, Shima Tavallaie, Marzieh Emamian and Amirhossein Sahebkar*


DOI: 10.2174/1871529X19666190919110652
View Abstract View on PubMed


Abstracts Ahead of Print

Published Contents

Editor's Choice

Comprehensive Review on Diabetes Associated Cardiovascular Complications - The Vitamin D Perspective

, 2019; 19(2): 139 - 153

Y. Durgarao, Poornima A. Manjrekar*, Prabha Adhikari, M. Chakrapani and M.S. Rukmini


DOI: 10.2174/1871529X19666190114155302



Role of AMPK in Diabetic Cardiovascular Complications: An Overview

, 2019; 19(1): 5 - 13

Karthika Nellaiappan, Veera Ganesh Yerra and Ashutosh Kumar*


DOI: 10.2174/1871529X18666180508104929




Sodium-glucose Cotransporter 2 Inhibitors: Nephroprotective Impact on Diabetic Kidney Disease

, 2018; 18(2): 120 - 126

Konstantinos Stavropoulos*, Konstantinos P. Imprialos, Nikiforos Stavropoulos, Sofia Bouloukou, Georgios Kerpiniotis, Kyriakos Dimitriadis, Constantinos Tsioufis and Michael Doumas


DOI: 10.2174/1871529X18666180206155349




Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation

, 2017; 17(3): 195 - 204

Mohammad Al-Ani, Sriram Ambadapadi, Jordan R. Yaron, Donghang Zheng, Adisson Fortunel, Maia Doroton-Guevara, Liying Liu, Sufi Morshed, Jay Fricker, William Miles, Matthew McKillop and Alexandra Lucas*


DOI: 10.2174/1871529X17666170918140442






Neuroinflammation in Sepsis: Sepsis Associated Delirium

, 2015; 15(1): 10 - 18

Simone Piva, Victoria A. McCreadie and Nicola Latronico


DOI: 10.2174/1871529X15666150108112452



Open Access Articles

Prognostic Value of Cardiac Biomarkers Assessment in Combination with Myocardial 2D Strain Echocardiography for Early Detection of Anthracycline-Related Cardiac Toxicity

, 2020; 20(1): 74 - 83

Mohammad P. Mahjoob, Seyed A. Sheikholeslami, Morvarid Dadras, Hamdollah Mansouri, Mahshid Haghi, Mohammadreza Naderian, Leila Sadeghi, Mohammadreza Tabary* and Isa Khaheshi*




Effect of Terebinthus atlanticus on Glucose Metabolism in Diabetic Rats

, 2020; 20(1): 31 - 40

Fadwa El-Ouady, Lhoussaine Hajji and Mohamed Eddouks*




Bivalirudin Versus Heparin During Intervention in Acute Coronary Syndrome: A Systematic Review of Randomized Trials

, 2020; 20(1): 3 - 15

Sukhdeep Bhogal, Debabrata Mukherjee, Jayant Bagai, Huu T. Truong, Hemang B. Panchal, Ghulam Murtaza, Mustafa Zaman, Rajesh Sachdeva and Timir K. Paul*





P Wave Dispersion and Silent Atrial Fibrillation in Cryptogenic Stroke: The Pathogenic Role of Inflammation

, 2019; 19(3): 249 - 252

Maurizio Acampa*, Pietro E. Lazzerini, Francesca Guideri, Rossana Tassi, Alessandra Cartocci and Giuseppe Martini




Genetics of Atrial Fibrilation: In Search of Novel Therapeutic Targets

, 2019; 19(3): 183 - 194

Estefanía Lozano-Velasco, Carlos Garcia-Padilla, Amelia E. Aránega and Diego Franco*




Glucose Lowering Activity of Aqueous Ammodaucus leucotrichus Extract in Diabetic Rats

, 2019; 19: 1 - 8 (E-Pub Ahead of Print)

Fadwa El-ouady and Mohamed Eddouks*




Red Blood Cells are Appropriate Carrier for Coagulation Factor VIII

, 2019; 19: 1 - 7 (E-Pub Ahead of Print)

Fatemeh Sayyadipour, Naser Amirizadeh, Arezoo Oodi, Masoud Khalili and Fakhredin Saba*




Effect of Curcumin on Serum Cathepsin D in Patients with Metabolic Syndrome

, 2019; 19: 1 - 6 (E-Pub Ahead of Print)

Leila Shirmohammadi, Majid Ghayour-Mobarhan*, Maryam Saberi-Karimian, Mehrdad Iranshahi, Shima Tavallaie, Marzieh Emamian and Amirhossein Sahebkar*




Total Ankle Replacement in Hemophilia

, 2019; 19: 1 - 5 (E-Pub Ahead of Print)

E. Carlos Rodriguez-Merchan*







Neuroinflammation in Sepsis: Sepsis Associated Delirium

, 2015; 15(1): 10 - 18

Simone Piva, Victoria A. McCreadie and Nicola Latronico






Most Cited Articles

Review Article

Nanoparticle based treatment for cardiovascular diseases

, 2019; 19(1): 33-44.

Purnima Gupta, Evelyn Garcia, Amrita Sarkar, Sumit Kapoor, Khadija Rafiq, Hitendra S. Chand and Rahul Dev Jayant*


DOI: 10.2174/1871529X18666180508113253


Review Article

Humoral immunity in heart failure

, 2019; 19(1): 14-18.

Amrita Sarkar and Khadija Rafiq*


DOI: 10.2174/1871529X18666180518101527



Research Article

P wave dispersion and silent atrial fibrillation in cryptogenic stroke: The pathogenic role of inflammation

, 2019; 19(3): 249-252.

Maurizio Acampa*, Pietro E. Lazzerini, Francesca Guideri, Rossana Tassi, Alessandra Cartocci and Giuseppe Martini


DOI: 10.2174/1871529X19666190410145501


Review Article

Adenosine as a marker and mediator of cardiovascular homeostasis: A translational perspective

, 2019; 19(2): 109-131.

Trevor Simard, Richard Jung, Alisha Labinaz, Mohammad Ali Faraz, F. Daniel Ramirez, Pietro Di Santo, Ian Pitcher, Pouya Motazedian, Chantal Gaudet, Rebecca Rochman, Jeffrey Marbach, Paul Boland, Kiran Sarathy, Saleh Alghofaili, Juan J. Russo, Etienne Couture, Rob S. Beanlands and Benjamin Hibbert*


DOI: 10.2174/1871529X18666181011103719


Review Article

Recent advances in understanding the pathogenesis of cardiovascular diseases and development of treatment modalities

, 2019; 19(1): 19-32.

Rahul Mittal*, Vasanti M. Jhaveri, Sae-In Samantha Kay, Aubrey Greer, Kyle J. Sutherland, Hannah S. McMurry , Nicole Lin, Jeenu Mittal, Arul K. Malhotra and Amit P. Patel


DOI: 10.2174/1871529X18666180508111353


Research Article

Pseudomonas aeruginosa invades human aortic endothelial cells and induces cell damage in vitro

, 2019; 19(1): 45-50.

Rahul Mittal*, Vasanti M. Jhaveri, Sae-In Samantha Kay, Patricia Blackwelder and Kunal Patel


DOI: 10.2174/1871529X18666180611094928


Review Article

Role of AMPK in diabetic cardiovascular complications: An overview

, 2019; 19(1): 5-13.

Karthika Nellaiappan, Veera Ganesh Yerra and Ashutosh Kumar*


DOI: 10.2174/1871529X18666180508104929



Case Report

Carfilzomib: A tale of a heartbreaking moment: Case report and concise review of the literature

, 2019; 19(3): 253-258.

W. Serra*, A. Fantin , C. Longo , G. Rabia , F. De Rosa, C. Plenteda , F. Re , E. Crisafulli and A. Chetta


DOI: 10.2174/1871529X19666181205100705


Research Article

Relationship between single-nucleotide polymorphisms of tumor necrosis factor alpha, interleukin-10, factor II and factor V with risk of inhibitor development in patients with severe hemophilia a

, 2019; 19(3): 228-232.

Shahrzad Soori, Ghazaleh Dadashizadeh, Akbar Dorgalaleh, Shadi Tabibian, Mohammad R. Keramati, Shaban Alizadeh, Maryam S. Hosseini, Farhad Zaker* and Mahmood Shams


DOI: 10.2174/1871529X19666190206152315


Review Article

CD123: A novel biomarker for diagnosis and treatment of leukemia

, 2019; 19(3): 195-204.

Mingyue Shi, Ruijun J. Su, Kamal-Preet Parmar, Rahman Chaudhry, Kai Sun, Jianyu Rao and Mingyi Chen*


DOI: 10.2174/1871529X19666190627100613


Review Article

Genetics of atrial fibrilation: In search of novel therapeutic targets

, 2019; 19(3): 183-194.

Estefanía Lozano-Velasco, Carlos Garcia-Padilla, Amelia E. Aránega and Diego Franco*


DOI: 10.2174/1871529X19666190206150349



Systemic Review Article

Blood biomarkers for the differentiation of cardiac ischemic stroke subtypes: A systematic review

, 2019; 19(3): 215-227.

Abhishek Pathak*, Surya P. Pandey, Prasoon Madhukar, Priya Dev, Deepika Joshi, Vijay N. Mishra and Rameshwar N. Chaurasia


DOI: 10.2174/1871529X18666180829142354



Most Accessed Articles

Impact of the Fontan Operation on Organ Systems

, 2019; 19(3): 205-214.

Miriam Michel*, Manuela Zlamy, Andreas Entenmann, Karin Pichler, Sabine Scholl-Bürgi, Daniela Karall, Ralf Geiger, Christina Salvador, Christian Niederwanger and Hideo Ohuchi


DOI: 10.2174/1871529X19666190211165124


Protective Effects of Curcumin Against Nephrotoxic Agents

, 2019; 19(3): 176-182.

Tahereh Farkhondeh, Saeed Samarghandian*, Mohsen Azimi-Nezhad and Ali M.P. Shahri


DOI: 10.2174/1871529X18666180905160830


Genetics of Atrial Fibrilation: In Search of Novel Therapeutic Targets

, 2019; 19(3): 183-194.

Estefanía Lozano-Velasco, Carlos Garcia-Padilla, Amelia E. Aránega and Diego Franco*


DOI: 10.2174/1871529X19666190206150349


CD123: A Novel Biomarker for Diagnosis and Treatment of Leukemia

, 2019; 19(3): 195-204.

Mingyue Shi, Ruijun J. Su, Kamal-Preet Parmar, Rahman Chaudhry, Kai Sun, Jianyu Rao and Mingyi Chen*


DOI: 10.2174/1871529X19666190627100613


Blood Biomarkers for the Differentiation of Cardiac Ischemic Stroke Subtypes: A Systematic Review

, 2019; 19(3): 215-227.

Abhishek Pathak*, Surya P. Pandey, Prasoon Madhukar, Priya Dev, Deepika Joshi, Vijay N. Mishra and Rameshwar N. Chaurasia


DOI: 10.2174/1871529X18666180829142354


Carfilzomib: A Tale of a Heartbreaking Moment: Case Report and Concise Review of the Literature

, 2019; 19(3): 253-258.

W. Serra*, A. Fantin , C. Longo , G. Rabia , F. De Rosa, C. Plenteda , F. Re , E. Crisafulli and A. Chetta


DOI: 10.2174/1871529X19666181205100705


Relationship Between Single-Nucleotide Polymorphisms of Tumor Necrosis Factor Alpha, Interleukin-10, Factor II and Factor V with Risk of Inhibitor Development in Patients with Severe Hemophilia A

, 2019; 19(3): 228-232.

Shahrzad Soori, Ghazaleh Dadashizadeh, Akbar Dorgalaleh, Shadi Tabibian, Mohammad R. Keramati, Shaban Alizadeh, Maryam S. Hosseini, Farhad Zaker* and Mahmood Shams


DOI: 10.2174/1871529X19666190206152315



Role of AMPK in Diabetic Cardiovascular Complications: An Overview

, 2019; 19(1): 5-13.

Karthika Nellaiappan, Veera Ganesh Yerra and Ashutosh Kumar*


DOI: 10.2174/1871529X18666180508104929





Editor-in-Chief

Garry X. Shen
University of Manitoba
Winnipeg, MB
Canada

Biography View Full Editorial Board

Journal History

Cardiovascular and Hematological Disorders-drug Targets was launched in 2001. Dr. Garry X. Shen serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.46

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