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Central Nervous System Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Central Nervous System Agents

Volume 19, 3 Issues, 2019
ISSN: 1875-6166 (Online)
ISSN: 1871-5249 (Print)
This journal supports open access

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Conflict of Interest

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Co-Editors cnsamc_ebm_hamilton_001 Hamilton G.S. Biopharma Research Leader, Organic and Medical Chemist, Registered US Patent Agent Catonsville MD USA Dr. Gregory received his bachelor’s and PhD degrees in chemistry from the University of Virginia and worked on the synthesis of complex indole alkaloids. In 1988, he joined Nova Pharmaceuticals Inc. He became the Vice President of Chemistry in 1997. In 2002, as Vice-President, he joined Artesian Therapeutics in Gaithersburg and designed and patented an IND candidate in a year. In 2005, he joined MGI PHARMA, as head of the medicinal chemistry. In 2007, he became the Senior Director of Intellectual Property, and in 2008, he worked as senior member of IP group cnsamc_ebm_aliev_001 Aliev G. "GALLY" International Biomedical Research Consulting LLC San Antonio TX USA Dr. Gjumrakch Aliev, MD, PhD, President “GALLY” International Biomedical Research Institute Inc., San Antonio, Texas, USA. He also hold appointment with the University of Atlanta, as a Professor and as a Leading Scientist , Institute of Physiologically Active Compounds. Russian Academy of Sciences. He received his MD in 1982, from the Baku Medical University (former USSR) with cum laude. Then he accomplished his PhD in Cardiovascular Diseases from the prestigious Russian Academy of the Medical Sciences, Moscow, Russia in 1988 with cum laude. He authored and coauthored more than 500 publications in the fields of neurodegenerative diseases research (Alzheimer disease), as well as cardio- and cerebrovascular disease, cancer, and electron microscopy. Associate Editors cnsamc_ae_mariottini_001 Mariottini G.L. University of Genova Genova Italy MSc and MD, fellow of the Provincial Medical and Odontological Register (Genova), of the Italian Society of Experimental Biology and of the Solidarity, Projects and Resources for Africa University Board. He worked at the G.Gaslini Pediatric Hospital of Genova carrying out research on neuroblastoma; at present he deals with ecotoxicology, toxicology, and natural extract activity on cultured cells at the University of Genova (Department of Earth, Environment and Life Sciences). He participated in national and international research projects and working groups, is Associate Editor, Editorial Board member and reviewer for international scientific journals, Guest Editor for special issues of journals and books, and author of 152 publications, including 9 teaching books. cnsamc_ebm_zelena_001 Zelena D. Hungarian Academy of Sciences, Institute of Experimental Medicine Gvadányi Hungary Dr. Zelena is a medical doctor (MD) and obtained a doctorate (PhD) in Neuroscience from the Semmelweis University, Budapest, Hungary. She has more than 20 years of experience in the research for new treatment option aimed to treat CNS and neurological disorders. Currently Dr. Zelena is a Senior Scientist of the Hungarian Academy of Sciences, Institute of Experimental Medicine. She is a neuroendocrinologist, and behavioral neuroscientist. Dr. Zelena is also an adjunct faculty member at University of Pécs, Hungary, where she teaches Physiology to medical students. She published more than 95 articles and 14 book chapters. cnsamc_ebm_bachurin_001 Bachurin S.O. Institute of Physiologically Active Compounds Russian Academy of Sciences (IPAC RAS) Moscow Russia Sergey Bachurin received the Ph.D. degree in 1980. Since 1981 he works in the Institute of Physiologically Active Compounds Russian Academy of Sciences (RAS). Since 2006 he is a Director of the Institute. In 2003 he was elected as a member of RAS. His research activity related to the discovery of novel agents for neurodegenerative diseases treatment. Bachurin was invited scholar in University of California, San Francisco and in Tufts University, Boston. He is Russian national representative in IUPAC and Council member of European Federation of Medicinal Chemistry. He is the author of more than 200 and about 40 patents. cnsamc_ebm_neumeyer_001 Neumeyer J.L. McLean Hospital Belmont MA USA Dr. Neumeyer received his BS in Chemistry from Columbia University and PhD in Medicinal Chemistry from the University of Wisconsin, Madison, WI. He joined the faculty of Northeastern University as Professor of Medicinal Chemistry and was appointed Matthews Distinguished Professor. Dr. Neumeyer was a cofounder of Research Biochemicals, Inc. Dr. Neumeyer has had a long career in medicinal chemistry as evidenced in more than 400 scientific publications. He is currently the director of the Medicinal Chemistry Laboratory at McLean Hospital, Harvard Medical School. Dr. Neumeyer was inducted into the American Chemical Society’s Division of Medicinal Chemistry Hall of Fame in 2008. Regional Editors Asia cnsamc_ebm_hashioka_001 Hashioka S. Shimane University Izumo Japan Dr. Sadayuki Hashioka is an associate professor of Department of Psychiatry, Shimane University, Izumo, Japan. He received his MD in 1998 from the Faculty of Medicine, University of Miyazaki, Japan. After four years of clinical work as a psychiatrist, he received his PhD in 2006 from the Department of Neuropsychiatry, Kyushu University, Fukuoka, Japan.He subsequently obtained five-year training as a postdoctoral fellow under Drs. Edith and Patrick McGeer at the Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, Canada. Since 2012 he has been at his present post cnsamc_ebm_d-wang_001 Wang D.Q. Zhujiang Hospital of Southern Medical University Guangzhou China Prof. D.Q. Wang is Vice-Head at the Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University. He obtained his Ph. D from National University of Singapore and he is Postdoctoral Fellow at Stanford University and NHMRC from Australia. He is regular a member of Asia Pacific Society for Neurochemistry, NSFC of China Grant and Committee Member of Chinese Parkinson‘s Disease & Movement Disorders Society, “Frontiers in Cellular Neuroscience”. He was awarded as Young Investigator in 2010 from Ministry of Education. He obtained 26 National Grants and has published 45 SCI papers. Europe cnsamc_ebm_cacabelos_001 Cacabelos R. Camilo José Cela University Madrid Spain Dr. Ramón Cacabelos is Professor of Genomic Medicine at Camilo José Cela University, Madrid, and President of the EuroEspes Biomedical Research Center, Corunna, Spain. He received his M.D. from Oviedo University, Ph.D. from Santiago University, and D.M.Sci. (Psychiatry) from Osaka University Medical School, Japan. After a decade at the Department of Psychiatry in Osaka, he returned to Spain and focused his research activity on the genomics and pharmacogenomics of neurodegenerative disorders. He has published over 600 papers and 24 books, and is Editor-in-Chief of the first World Guide for Drug Use and Pharmacogenomics and President of the World Association of Genomic Medicine. North America cnsamc_ebm_fatem_001 Fatemi S.H. University of Minnesota Medical School Minneapolis MN USA M. Fatemi received his PhD in Electrical Engineering from Purdue University. Currently, he is a Professor of Biomedical Engineering at the Mayo Clinic College of Medicine, and a member of Mayo Clinic Cancer Center, Cancer Imaging Program, and the Center for Translational Science Activities. In addition, he is a faculty member of the Biomedical Informatics and Computational Biology graduate program at the University of Minnesota Rochester. His current research areas include ultrasonic methods for tissue viscoelasticity and nonlinear elasticity estimation for applications in cancer imaging and bladder function evaluation. He is an elected Fellow of IEEE, AIMBE, ASA, and AIUM. He is the recipient of the IEEE-UFFC Distinguished Lecturer award for 2016-2017. Frontiers Section Editor cnsamc_ebm_utkin_001 Utkin Y.N. Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences (IBCH RAS) Moscow Russia Yuri N. Utkin received his PhD in Bioorganic Chemistry from the Shemyakin Institute of Bioorganic Chemistry of the Academy of Sciences of the USSR. After earning the PhD degree he continued his career at the same Institute (now the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS), receiving a DSc degree in 1996 and being promoted to Professor in 2006. Prof. Utkin is the head of the laboratory of molecular toxinology. He has published more than 150 scientific publications in peer reviewed journals. Professor Utkin is a member of the European Society for Neurochemistry, the International Society on Toxinology, and the American Society for Biochemistry and Molecular Biology. Bioorganic Chemistry Editorial Board Members cnsamc_ebm_vale-c_001 Vale C. University of Santiago de Compostela Lugo Spain Associate Professor University of Santiago de Compostela, Faculty of Veterinary, Lugo. Degree in Pharmacy, University of Santiago de Compostela. PhD in Pharmacy, Neurochemistry, University of Barcelona (1998): neurotoxicity of organic pollutants. Postdoctoral stay at the Center for Neural Science, New York University. Supervisor: Dan H. Sanes. Study of synaptic plasticity in the auditory system (1998-2000). Associate Professor, Faculty of Medicine, University of Castilla-La Mancha (2000-2004). 2004-Present: Study of marine toxins in neuronal systems, Universidade de Santiago de Compostela. cnsamc_ebm_gentile_001 Gentile V. University of Campania "Luigi Vanvitelli" Naples Italy Dr. Gentile is a recognized expert in the transglutaminase research area and has a strong background in the molecular biology and biochemical aspects of the transglutaminase (TG) enzymes expression, activity and function. His work has been focused to the tTG (TG2) characterization in normal and pathological cellular events (cell growth and differentiation, adhesion, apoptosis, neurodegeneration) by biochemical and molecular biology studies. Currently dr. Gentile is associate professor at the University of Campania “Luigi Vanvitelli” . cnsamc_ebm_tiwari-rk_001 Tiwari R.K. Chapman University Irvine CA USA Dr. Rakesh Kumar Tiwari is currently an Assistant Professor of Biopharmaceutical and Biomedical Sciences. He joined CUSP in September 2013. He received his Ph.D. (2006) in Organic Chemistry from Dr. B.R. Ambedker Center for Biomedical Research, University of Delhi. In 2007, Dr. Tiwari’s strong interest to conduct research in the area of application of chemistry in biology led him to pursue his postdoctoral research at University of Rhode Island. His postdoctoral work resulted in the synthesis of several peptide as neuroprotective agents, nanomaterials, kinase inhibitors as anticancer compounds, and many cell-penetrating peptide. cnsamc_ebm_macchi-b_001 Macchi B. University of Rome Tor Vergata Rome Italy Dr. Beatrice Macchi is Assistant Professor in the Pharmacology Section of Department of Systems Medicine at University of Rome Tor Vergata, Italy. She is also Principal Investigator of the laboratory of molecular antiviral research in the Department of System Medicine, at University of Rome Tor Vergata. Her skills and expertise mainly lie in the subject areas of PCR, Cell Culture, Cancer Biology, Flow Cytometry, Proteins, Biotechnology, Infection, Apoptosis, Immunology of Infectious Diseases, HIV, Cancer Research, etc. Dr. Macchi, as an author/co-author, has published more than 90 articles in various journals, having over 1,200 total citations. cnsamc_ebm_bottai-d_001 Bottai D. University of Milan Milan Italy Dr. Bottai has obtained Ph.D. in Neuroscience from the University of Pisa, Italy and McGill University, Montreal, Quebec, Canada. He is presently working as an Assistant Professor in Pharmacology, Department of Science Health University of Milan. He is Ordinary member of the Italian Society of Pharmacology. He is in Collaboration with International Scientific Journals such as Reviewer of The Lancet, Journal of Neurochemistry, Associated Editor: Frontiers in Stem Cells Treatments and Associated Editor: Frontiers in Cell and Developmental Biology. He has contributed more than 30 publications, having citations around 946. cnsamc_ebm_meccariello-r_001 Meccariello R. University of Naples Parthenope Naples Italy Dr. Meccariello obtained her Degree in Biology at the University of Naples Federico, Italy in 1997. She further got Ph.D. in Comparative Endocrinology at the University of Padova, Italy in 2004. She is presently serving as an Associate Professor of Biology at the Department of Movement and Wellness Sciences at Parthenope University of Naples, Italy. Her field of expertise is in Biology of reproduction, reproductive endocrinology, spermatogenesis, sperm quality, hypothalamus - pituitary - gonad (HPG) axis, endocannabinoids, endocrine disruptor chemicals, central and local regulation of testicular activity in vertebrates. She has contributed more than 80 publications, having citations around 1495. cnsamc_ebm_galeazzi-r_001 Galeazzi R. Marche Polythecnic University Ancona Italy Dr. Roberta Galeazzi got the Chemistry degree in 1992 at the University of Bologna cum laude and worked as researcher since January 1993 at the Polytechnic Marche University where actually she is assistant professor (SSD CHIM/06) of the Department of Life and Environmental Science (DISVA). Dr. Galeazzi’s main research activity concerns molecular docking and molecular dynamics profiling of novel active compounds or natural ligands to their receptors with the aim of rationalize the molecular basis of biological processes fundamental for the transductions of specific biochemical and physiological effects. She is co-author of 80 papers published on international peer-review journals and she attended to many congresses with oral and poster presentations. cnsamc_ebm_sesti_001 Sesti F. Robert Wood Johnson Medical School Piscataway NJ USA Dr. Federico Sesti is a Professor of Neuroscience and Cell Biology, Rutgers University. He received his Laurea and Ph.D. in Physics from the University of Genova, Italy. He was a postdoctoral fellow in the laboratory of Benjamin Kaupp, Institut für Biologische Informationsverarbeitung, Forschungszentrum Jülich (Germany) and in the laboratory of Steve Goldstein at Yale University (USA). He is a Fulbrigh Scholar, and member of several scientific societies. He serves in the editorial board of several journals and in international, federal and private funding agencies. cnsamc_ebm_betti_001 Betti L. University of Pisa Pisa Italy Dr. Laura Betti, obtained a PhD in Neurobiology and Clinic of Affective Disorders from the University of Pisa, Italy. In the same University she also received her Speciality in Clinical Biochemistry and her Biological Degree. Currently Dr. Betti is Researcher in Biochemistry at the Department of Pharmacy of the University of Pisa. She has over 20 years of the experience in the research of proteins and their role in transduction mechanisms in physiological and pathological conditions. She has published 100 publications in the fields of biochemistry, as well as clinical biochemistry and neurosciences with particular reference to neurotransmitters and receptor systems. cnsamc_ebm_corelli_001 Corelli F. Universita' degli Studi de Siena Siena Italy F. Corelli was born in Italy. He graduated in Medicinal Chemistry at University of Rome La Sapienza and joined Artico's group. He served as the Chairman of the University of Siena and was appointed in the Scientific Committee of University of Pisa. He was the director of the Workshop in Synthetic Metodologies of the Italian Chemical Society. He is a member of the Steering Committee of the Italian Chemical Society, EABM of Central Nervous System Agents in Medicinal Chemistry and a reviewer for numerous scientific journals. He is the author of 8 patent applications, 198 scientific papers, 8 book chapters , more than 90 oral/poster communications. He has also been editor of a book. cnsamc_ebm_horti_001 Horti A.G Johns Hopkins University Baltimore MD USA Dr. Horti is an Associate Professor in the Department of Radiology and Radiological Science at Johns Hopkins University, Maryland. He has devoted his career to the development of short-lived radiotracers for PET, in particular radioligands for imaging of cerebral receptors and enzymes in human subjects. His scientific results have been published in various peer-reviewed journals, invited reviews supported by NIH, private foundations and pharmaceutical industry. He also holds appointments on editorial boards for several scientific journals. He is an active member of the Society of Nuclear Medicine and Molecular Imaging and he has organized research sessions and continuing education sessions for a number of SNMMI meetings. cnsamc_ebm_hulme_001 Hulme C. University of Arizona Oro Valley AZ USA Dr. Hulme received a doctorate degree (D.Phil) in chemistry from the University of Oxford, England. He currently is a full Professor at the University of Arizona and Director of the Medicinal Chemistry BIO5 Drug Discovery Core. Prior to moving to academia, Dr. Hulme built and managed several high-throughput medicinal chemistry organizations in industry (1994 – 2007, Sanofi, Amgen, Lilly), spanning a multitude of therapeutic areas including neurodegeneration through the targeting of CNS kinases. Dr Hulme has > 175 publications, book chapters, and patents. Malawska B. University Collegium Medicum Kraków Poland Okun I. Biology and CTO San Diego CA USA cnsamc_ebm_parang_001 Parang K. Chapman University Orange CA USA Dr. Parang is Associate Dean of Research, Graduate Studies and Global Affairs and a Full Professor of Medicinal Chemistry and Pharmacology at Chapman University School of Pharmacy in Irvine, California. He earned a Pharm.D. degree from Tehran University of Medical Sciences in 1989. He received his Ph.D. in medicinal chemistry from the Faculty of Pharmacy at University of Alberta in 1997, followed by a postdoctoral study in the fields of carbohydrate chemistry and solid-phase organic synthesis in Department of Chemistry. He pursued additional postdoctoral studies at Rockefeller University in New York and Johns Hopkins University in Baltimore in bioorganic chemistry. He is an author of 170 peer-reviewed publications, 8 patents, and more than 140 meeting. cnsamc_ebm_ramassamy_001 Ramassamy C. INRS-Institute Armand-Frappier Montreal QC Canada Prof. Charles Ramassamy has successively obtained his DEA (Diploma of Advanced Studies) in Molecular and Cellular Pharmacology at Paris V University, and a PhD in Neuroscience, option neuropharmacology, at the University of Rouen in France. After completing a postdoctoral fellowship at McGill University, at the Douglas Mental Health University Institute Research Center in the laboratory of Dr. Judes Poirier, he became professor of pharmacology at the Université du Québec à Trois-Rivières, then professor at the INRS-Institut Armand-Frappier. He is also an associate professor at Laval University and a regular researcher at the Institute on Nutrition and Functional Foods, Laval University. cnsamc_ebm_shaun_001 Stauffer S.R. Vanderbilt University Medical Center Nashville TN USA Dr. Shaun Stauffer is currently Assistant Professor in the departments of Pharmacology and Chemistry at Vanderbilt University and is associate director of medicinal chemistry within the Vanderbilt Institute for Chemical Biology (VICB) Synthesis Core. Dr. Stauffer received his Ph.D. in 1999 from the University of Illinois developing combinatorial approaches towards selective estrogen receptor modulators in the laboratory of Prof. John Katzenellenbogen. Dr. Stauffer then pursued post-doctoral studies at Yale University as an NIH fellow with Prof. John Hartwig (1999-2001) developing highthroughput screening platforms for reaction discovery and optimization. From 2001-2008 he pursued an industrial career at Merck & Co. Associate Editorial Board Member cnsamc_ebm_noorbakhshnia-ah_001 Noorbakhshnia M. University of Isfahan Isfahan Iran Dr. Maryam Noorbakhshnia is currently an Assistant Professor at the University of Isfahan (Research and teaching different physiology courses to bachelor and master students). She did Ph.D. from Tehran University in 2007 (Major: physiology of the nervous system). Before that, she did her MSc from Tehran University in the year 2000 (Major: physiology of the nervous system). Executive Guest Editor(s) mrmc_ebm_v-gentile_001 Gentile V. University of Campania "Luigi Vanvitelli" Naples Italy Dr. Gentile (Naples, Italy) is a recognized expert in the transglutaminase research area and has a strong background in the molecular biology and biochemical aspects of the transglutaminase (TG) enzymes expression, activity and function. His work has been focused to the tissue TG (TG2) characterization in normal and pathological cellular events (cell growth and differentiation, adhesion, apoptosis, neurodegeneration) by molecular biology, immunological and biochemical studies. Currently he works as associate professor at the University of Campania “Luigi Vanvitelli”.

Journal History

Current Medicinal Chemistry - Central Nervous System Agents was launched in 2001 and later renamed in 2006 as Central Nervous System Agents in Medicinal Chemistry.
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