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Current Clinical Pharmacology

Volume 14, 3 Issues, 2019
ISSN: 2212-3938 (Online)
ISSN: 1574-8847 (Print)
This journal supports open access

Aims & Scope

Current Clinical Pharmacology publishes full-length /mini reviews and original research articles on all the latest advances in clinical pharmacology. The journal aims to publish the highest quality original research and review articles, drug clinical trial studies and guest edited thematic issues in the field. Topics covered include: pharmacokinetics; therapeutic trials; adverse drug reactions; drug interactions; drug metabolism; pharmacoepidemiology; and drug development. The journal is essential reading for all researchers in clinical pharmacology.

Current Clinical Pharmacology

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Volume 14

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Number 1



Biography   Open Access



Preface   Open Access



Review Article   Open Access



Review Article



Review Article



Review Article   Open Access



Research Article

Role of Nrf2/HO-1 and PI3K/Akt Genes in the Hepatoprotective Effect of Cilostazol

, 14(1): 61 - 67

Marwa Hassan*, Mohamad A. Ibrahim, Heba M. Hafez, Mervat Z. Mohamed, Nagwa M. Zenhom and Hend M. Abd Elghany


DOI: 10.2174/1574884713666180903163558


Research Article



Articles Ahead of Print


Minocycline Increases in-vitro Cortical Neuronal Cell Survival after Laser Induced Axotomy


Burak Yulug*, Mehmet Ozansoy, Merve Alokten, Muzaffer Beyza Cetin Ozansoy, Seyda Cankaya, Lutfu Hanoglu, Ulkan Kilic and Ertugrul Kilic


View Abstract View on PubMed


Concomitant use of Cotrimoxazole and Atazanavir in HIV-infected Patients: A Therapeutic Drug Monitoring and Pharmacovigilance Based Dual Approach


Miantezila Basilua Joe*, Landman Rolandc, Chouchana Laurentg, Lê Minh Patrick, Olivier Sawoo, Tona Lutete Gastonf , Eto Brunoe , Peytavin Gilles and Pochart Philippe


View Abstract View on PubMed



Drug-Induced Peripheral Neuropathy, A Narrative Review


Mark R. Jones*, Ivan Urits, John Wolf, Devin Corrigan, Luc Colburn, Emily Peterson, Amber Williamson and Omar Viswanath


View Abstract View on PubMed


Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid Addicted Patients under General Anesthesia


Farzaneh Mahikhan*, Morteza Hashemian, Tania Dehesh, Elham Jafari*, Mandana Jafari* and Hamid Reza Rahimi


View Abstract View on PubMed



The Effect of Methylphenidate on Reed Scaling in Benzodiazepine Poisoning: A Prospective Trial


Masoud Latifi-Pour, Hossein Hassanian-Moghaddam, Helya-Sadat Mortazavi, Shahin Shadnia, Nasim Zamani and Mitra Rahimi*


View Abstract View on PubMed




Abstracts Ahead of Print

Melatonin modulates regulation of NOX2 and NOX4 following irradiation in the lung


Masoud Najafi, Alireza Shirazi*, Elahe Motevaseli*, Ghazale Geraily, Peyman Amini, Leila Farhadi Tooli and Dheyauldeen Shabeeb


View Abstract


Surotomycin (a novel cyclic lipopeptide) vs Vancomycin for treatment of Clostridioides difficile infection: A systematic review and Meta-analysis


Muhammad Aziz*, Madhav Desai, Rawish Fatima, Viveksandeep Thoguluva Chandrasekar, Albert Eid, Mollie Jackson and Prateek Sharma


View Abstract


Investigation of the roles of new antiepileptic drugs’ and serum BDNF levels in efficacy and safety monitoring and quality of life: a clinical research


Meral Demir*, Emel Oğuz Akarsu, Hava Özlem Dede, Nerses Bebek, Sevda Özel Yıldız, Betül Baykan and Ahmet Gökhan Akkan


View Abstract


Published Contents

Editor's Choice


A Critique of Computer Simulation Software’s Used in Pharmacokinetics and Pharmacodynamics Analysis

, 2018; 13(4): 216 - 235

Vivek Dave*, Renu Bala Yadav, Sachdev Yadav, Swapnil Sharma, Ram Kumar Sahu and Ayodeji Folorunsho Ajayi


DOI: 10.2174/1574884713666181025144845



Trends of Clinical Trials for Drug Development in Rare Diseases

, 2018; 13(3): 199 - 208

Ryuichi Sakate, Akiko Fukagawa, Yuri Takagaki, Hanayuki Okura and Akifumi Matsuyama*


DOI: 10.2174/1574884713666180604081349





Comparison of Two Naloxone Regimens in Opioid-dependent Methadoneoverdosed Patients: A Clinical Trial Study

, 2017; 12(4): 259 - 265

Navid Khosravi, Nasim Zamani, Hossein Hassanian-Moghaddam*, Ali Ostadi, Mitra Rahimi and Ali Kabir


DOI: 10.2174/1574884713666171212112540



Perioperative Management of Anticoagulants

, 2017; 12(3): 145 - 151

Joan M. Irizarry-Alvarado* and Lynsey A. Seim


DOI: 10.2174/1574884712666170822092709



Clonidine, but not Dexamethasone, Prolongs Ropivacaine-Induced Supraclavicular Brachial Plexus Nerve Block Duration

, 2017; 12(2): 92 - 98

Dawood Nasir*, Irina Gasanova, Shaina Drummond, John Alexander, Jo Howard, Emily Melikman, Gary Hill, Abu Minhajuddin, Babatunde Ogunnaike and Charles Whitten


DOI: 10.2174/1574884712666170605085508




Relationships Between Metformin, Paraoxonase-1 and the Chemokine (C-C Motif) Ligand 2

, 2016; 11(4): 250 - 258

Jordi Camps, Anna Hernandez-Aguilera, Anabel Garcia-Heredia, Noemi Cabre, Fedra Luciano-Mateo, Meritxell Arenas and Jorge Joven


DOI: 10.2174/1574884711666160915152941



Open Access Articles


Role of Nrf2/HO-1 and PI3K/Akt Genes in the Hepatoprotective Effect of Cilostazol

, 2019; 14(1): 61 - 67

Marwa Hassan*, Mohamad A. Ibrahim, Heba M. Hafez, Mervat Z. Mohamed, Nagwa M. Zenhom and Hend M. Abd Elghany




Metformin and Pregnancy Outcomes: Evidence Gaps and Unanswered Questions

, 2019; 14(1): 54 - 60

Claudio D. Gonzalez, Jorge Alvariñas, Maria F.G. Bagnes and Guillermo Di Girolamo*





Metformin as a Radiation Modifier; Implications to Normal Tissue Protection and Tumor Sensitization

, 2019; 14(1): 41 - 53

Keywan Mortezaee, Dheyauldeen Shabeeb, Ahmed E. Musa, Masoud Najafi* and Bagher Farhood*




Biosimilars: An Approach to some Current Worldwide Regulation Frameworks

, 2019; 14(1): 16 - 40

Efraín Esteban, Rosa-Helena Bustos*, Julio-César García and Edwin Jáuregui




Rabbit as an Animal Model for Pharmacokinetics Studies of Enteric Capsule Contains Recombinant Human Keratinocyte Growth Factor Loaded Chitosan Nanoparticles

, 2019; 14: 1 - 9 (E-Pub Ahead of Print)

Palanirajan Vijayaraj Kumar*, Marwan Abdelmahmoud Abdelkarim Maki, Yeong Siew Wei, Lee Ming Tatt, Manogaran Elumalai, Shiau-Chuen Cheah, Bharathy Raghavan and Abu Bakar Bin Abdul Majeed




Role of Muscarinic Acetylcholine Receptors in Breast Cancer: Design of Metronomic Chemotherapy

, 2019; 14: 1 - 9 (E-Pub Ahead of Print)

M E Sales *, A J Español , A R Salem , P Pulido Martínez , Y Sanchez and F Sanchez




Protective Effect of Selenium-L-methionine on Radiation-induced Acute Pneumonitis and Lung Fibrosis in Rat

, 2019; 14: 1 - 8 (E-Pub Ahead of Print)

Peyman Amini, Sedighe Kolivand, Hana Saffar, Saeed Rezapoor, Elahe Motevaseli*, Masoud Najafi*, Farzad Nouruzi, Dheyauldeen Shabeeb and Ahmed Eleojo Musa




The Possibility of Therapeutic Drug Monitoring of the Most Important Interactions in Nursing Homes

, 2019; 14: 1 - 5 (E-Pub Ahead of Print)

Pernille Schjøtt, Martina Šutovská and Jan Schjøtt*





The Effect of Methylphenidate on Reed Scaling in Benzodiazepine Poisoning: A Prospective Trial

, 2019; 14: 1 - 7 (E-Pub Ahead of Print)

Masoud Latifi-Pour, Hossein Hassanian-Moghaddam, Helya-Sadat Mortazavi, Shahin Shadnia, Nasim Zamani and Mitra Rahimi*




Drug-Induced Peripheral Neuropathy, A Narrative Review

, 2019; 14: 1 - 11 (E-Pub Ahead of Print)

Mark R. Jones*, Ivan Urits, John Wolf, Devin Corrigan, Luc Colburn, Emily Peterson, Amber Williamson and Omar Viswanath




Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid Addicted Patients under General Anesthesia

, 2019; 14: 1 - 9 (E-Pub Ahead of Print)

Farzaneh Mahikhan*, Morteza Hashemian, Tania Dehesh, Elham Jafari*, Mandana Jafari* and Hamid Reza Rahimi




Minocycline Increases in-vitro Cortical Neuronal Cell Survival after Laser Induced Axotomy

, 2019; 14: 1 - 5 (E-Pub Ahead of Print)

Burak Yulug*, Mehmet Ozansoy, Merve Alokten, Muzaffer Beyza Cetin Ozansoy, Seyda Cankaya, Lutfu Hanoglu, Ulkan Kilic and Ertugrul Kilic





Most Cited Articles

Review Article

Monoclonal antibodies: A review

, 2018; 13(2): 85-99.

Surjit Singh*, Nitish K. Kumar, Pradeep Dwiwedi, Jaykaran Charan, Rimplejeet Kaur, Preeti Sidhu and Vinay K. Chugh


DOI: 10.2174/1574884712666170809124728


Review Article

Determination of parameters of oxidative stress in vitro models of neurodegenerative diseases-A review

, 2018; 13(2): 100-109.

Chistiane Mendes Feitosa*, George Laylson da Silva Oliveira, Antonio do Nascimento Cavalcante, Soane Kaline Morais Chaves and Mahendra Rai


DOI: 10.2174/1574884713666180301091612


Research Article

Minocycline in alcohol withdrawal induced anxiety and alcohol relapse in rats

, 2018; 13(1): 65-72.

Snehalata V. Gajbhiye, Raakhi K. Tripathi*, Anup Petare, Anirudha V. Potey and Arun Shankar


DOI: 10.2174/1574884713666180228110310


Review Article

Targeting brain tumors with nanomedicines: Overcoming blood brain barrier challenges

, 2018; 13(2): 110-119.

Divya Khaitan, Polluru L. Reddy and Nagendra Ningaraj*


DOI: 10.2174/1574884713666180412150153




Review Article

Antibody-drug conjugates: A review on the epitome of targeted anti-cancer therapy

, 2018; 13(4): 236-251.

Mahmudul Hasan, Safaet Alam and Saikat Kumar Poddar*


DOI: 10.2174/1574884712666180802095521


Review Article

Approach for irritable bowel syndrome: Old and new

, 2018; 13(3): 164-172.

Paolo Usai-Satta*, Massimo Bellini , Mariantonia Lai , Francesco Oppia and Francesco Cabras


DOI: 10.2174/1574884713666180807143606



Review Article

Sglt-2 inhibitors in type 1 diabetes mellitus: A comprehensive review of the literature

, 2018; 13(4): 261-272.

Dimitrios Patoulias, Konstantinos Imprialos, Konstantinos Stavropoulos, Vasilios Athyros and Michael Doumas*


DOI: 10.2174/1574884713666180807150509


Review Article

Second-line treatment of advanced non-small cell lung cancer non-oncogene addicted: New treatment algorithm in the era of novel immunotherapy

, 2018; 13(2): 76-84.

Cesare Gridelli*, Paolo Antonio Ascierto, Francesco Grossi, Editta Baldini, Adolfo Favaretto, Maria Chiara Garassino, Alessandro Morabito, Maria Rita Migliorino, Antonio Rossi and Filippo de Marinis


DOI: 10.2174/1574884713666180711160008



Review Article

Lupus nephritis: A treatment update

, 2018; 13(1): 4-13.

Fahad Aziz and Kunal Chaudhary*


DOI: 10.2174/1574884713666180403150359


Research Article

Knowledge, attitudes, and practices of pharmacovigilance and ADRs spontaneous reporting among pediatricians and pediatric residents in Jordan

, 2018; 13(1): 45-54.

Tareq L. Mukattash*, Maysaa W. Alwadi, Rana K. Abu-Farha, Anan S. Jarab, Sameh A. Al-Zubiedi and Tareq Alwedyan


DOI: 10.2174/1574884713666180308151805


Review Article

A critique of computer simulation software’s used in pharmacokinetics and pharmacodynamics analysis

, 2018; 13(4): 216-235.

Vivek Dave*, Renu Bala Yadav, Sachdev Yadav, Swapnil Sharma, Ram Kumar Sahu and Ayodeji Folorunsho Ajayi


DOI: 10.2174/1574884713666181025144845



Most Accessed Articles

Monoclonal Antibodies: A Review

, 2018; 13(2): 85-99.

Surjit Singh*, Nitish K. Tank, Pradeep Dwiwedi, Jaykaran Charan, Rimplejeet Kaur, Preeti Sidhu and Vinay K. Chugh


DOI: 10.2174/1574884712666170809124728



Metformin as a Radiation Modifier; Implications to Normal Tissue Protection and Tumor Sensitization

, 2019; 14(1): 41-53.

Keywan Mortezaee, Dheyauldeen Shabeeb, Ahmed E. Musa, Masoud Najafi* and Bagher Farhood*


DOI: 10.2174/1574884713666181025141559


Metformin and Pregnancy Outcomes: Evidence Gaps and Unanswered Questions

, 2019; 14(1): 54-60.

Claudio D. Gonzalez, Jorge Alvariñas, Maria F.G. Bagnes and Guillermo Di Girolamo*


DOI: 10.2174/1574884714666181224151116


Biosimilars: An Approach to some Current Worldwide Regulation Frameworks

, 2019; 14(1): 16-40.

Efraín Esteban, Rosa-Helena Bustos*, Julio-César García and Edwin Jáuregui


DOI: 10.2174/1574884713666181025142928


Pharmacokinetic and Pharmacodynamic Relationship of Blinatumomab in Patients with Non-Hodgkin Lymphoma

, 2018; 13(1): 55-64.

Youssef Hijazi, Matthias Klinger, Andrea Kratzer, Benjamin Wu, Patrick A. Baeuerle, Peter Kufer, Andreas Wolf, Dirk Nagorsen and Min Zhu*


DOI: 10.2174/1574884713666180518102514


SGLT-2 Inhibitors in Type 1 Diabetes Mellitus: A Comprehensive Review of the Literature

, 2018; 13(4): 261-272.

Dimitrios Patoulias, Konstantinos Imprialos, Konstantinos Stavropoulos, Vasilios Athyros and Michael Doumas*


DOI: 10.2174/1574884713666180807150509



Determination of Parameters of Oxidative Stress in vitro Models of Neurodegenerative Diseases-A Review

, 2018; 13(2): 100-109.

Chistiane Mendes Feitosa*, George Laylson da Silva Oliveira, Antonio do Nascimento Cavalcante, Soane Kaline Morais Chaves and Mahendra Rai


DOI: 10.2174/1574884713666180301091612




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