Editor's Choice

Autophagy Inhibition in Childhood Nephroblastoma and the Therapeutic Significance

, 2018; 18(3): 295 - 303

Lin-Jie Li , Yi-Long Wang, Lin-Qing Yuan, Wei-Zhong Gu, Kun Zhu, Min Yang, Duo Zhou, Yao Lv, Min-Ju Li, Zheng-Yan Zhao, Jin-Hu Wang* and Xi Chen*

DOI: 10.2174/1568009617666170330105433

Oncolytic Viruses: The Best is Yet to Come

, 2018; 18(2): 109 - 123

Chantal G. Lemay, Brian A. Keller, Robert E. Edge, Masato Abei and John C. Bell*

DOI: 10.2174/1568009617666170206111609

Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation

, 2018; 18(1): 97 - 106

Samantha L. Martin, Rishabh Kala and Trygve O. Tollefsbol*

DOI: 10.2174/1568009617666170206104032

Coinhibitory Molecule PD-1 as a Therapeutic Target in the Microenvironment of Multiple Myeloma

, 2017; 17(9): 839 - 845

Djordje Atanackovic, Tim Luetkens, Sabari Radhakrishnan and Nicolaus Kroger*

DOI: 10.2174/1568009617666170906170348

Potential Therapeutic Targets in Energy Metabolism Pathways of Breast Cancer

, 2017; 17(8): 707 - 721

Rowshan Ara Islam, Sazzad Hossain and Ezharul Hoque Chowdhury*

DOI: 10.2174/1568009617666170330150458

Insight into Discovery of Next Generation Reversible TMLR Inhibitors Targeting EGFR Activating and Drug Resistant T790M Mutants

, 2017; 17(7): 617 - 636

Subhash Mohan Agarwal*, Divyani Pal, Mansi Gupta and Ravi Saini

DOI: 10.2174/1568009617666170330112842

Epstein-Barr Virus-associated Gastric Cancer and Potential Mechanisms of Oncogenesis

, 2017; 17(6): 534 - 554

Abigail Morales-Sanchez and Ezequiel M. Fuentes-Panana*

DOI: 10.2174/1568009616666160926124923

Identification of Novel Agents for the Treatment of Brain Metastases of Breast Cancer

, 2017; 17(5): 479 - 485

Vinay K. Venishetty, Werner J. Geldenhuys, Tori B. Terell-Hall, Jessica I.G. Griffith, Gregory R. Sondag, Fayez F. Safadi and Paul R. Lockman*

DOI: 10.2174/1568009617666161121123948

Hitting a Moving Target: Glioma Stem Cells Demand New Approaches in Glioblastoma Therapy

, 2017; 17(3): 236 - 254

Drew A. Spencer, Brenda M. Auffinger, Jason P. Murphy, Megan E. Muroski, Jian Qiao, Yureve Gorind and Maciej S. Lesniak

DOI: 10.2174/1568009616666161215161924

Targeting Key Metabolic Enzymes Involved in Lipid and Protein Biosyntheses for Breast Anticancer Therapies

, 2017; 17(2): 158 - 168

Mounia Guerram, Aida Mejda Hamdi, Lu-Yong Zhang and Zhenzhou Jiang

DOI: 10.2174/1568009616666160603123014

Does Hypoxic Response Mediate Primary Resistance to Sunitinib in Untreated Locally Advanced Breast Cancer?

, 2017; 17(1): 62 - 73

Sofia Braga, Joana Cardoso, Saudade Andre, Margarida Brito, Pedro Sanchez, Lurdes Orvalho, Lucilia Salgado, Sergio Dias, Jose B. Pereira-Leal and Jose Luis Passos-Coelho

DOI: 10.2174/1568009616666161025114914

Pyrimethamine as a Potent and Selective Inhibitor of Acute Myeloid Leukemia Identified by High-throughput Drug Screening

, 2016; 16(9): 818 - 828

Amit Sharma, Nidhi Jyotsana, Courteney K. Lai, Anuhar Chaturvedi, Razif Gabdoulline, Kerstin Görlich, Cecilia Murphy, Jan E. Blanchard, Arnold Ganser, Eric Brown, John A. Hassell, R. Keith Humphries, Michael Morgan and Michael Heuser

DOI: 10.2174/1568009616666160617103301

Deregulation of Apoptosis - Is it Still an Important Issue in Pathogenesis of Chronic Lymphocytic Leukemia?

, 2016; 16(8): 652 - 658

Monika Podhorecka, Arkadiusz Macheta, Maria Bozko, Andrzej Bozko, Nisar P. Malek and Przemyslaw Bozko

DOI: 10.2174/1568009616666160427103930

MT1-MMP Activation of TGF-β Signaling Enables Intercellular Activation of an Epithelial-mesenchymal Transition Program in Cancer

, 2016; 16(7): 618 - 630

Hoang-Lan Nguyen, Pournima Kadam, Alex Helkin, Kevin Cao, Song Wu, Ghassan J. Samara, Qian Zhang, Stanley Zucker and Jian Cao

DOI: 10.2174/1568009616666160216125634

Recent Advances in Site Specific Conjugations of Antibody Drug Conjugates (ADCs)

, 2016; 16(6): 469 - 479

Wenlong Gao, Jingxin Zhang, Jun Xiang, Lei Zhang, Chengbin Wu, Pradeep K. Dhal and Bo Chen

DOI: 10.2174/1568009616666160512144715

Mechanisms and Therapeutic Targets of microRNA-associated Chemoresistance in Epithelial Ovarian Cancer

, 2016; 16(5): 429 - 441

Lingyun Zhang, Lubna Nadeem, Kristin Connor and Guoxiong Xu

DOI: 10.2174/1568009616666160404121105

Targeted Inhibition of Rictor/mTORC2 in Cancer Treatment: A New Era after Rapamycin

, 2016; 16(4): 288 - 304

Zhipeng Zou, Juan Chen, Jun Yang and Xiaochun Bai

DOI: 10.2174/1568009616666151113120830

Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma

, 2016; 16(3): 261 - 274

Marilù Fanelli, Claudia Maria Hattinger, Serena Vella, Elisa Tavanti, Francesca Michelacci, Beth Gudeman, Daryl Barnett, Piero Picci and Massimo Serra

DOI: 10.2174/1568009616666151106120434

RING-, HECT-, and RBR-type E3 Ubiquitin Ligases: Involvement in Human Cancer

, 2016; 16(2): 157 - 174

Chiharu Uchida and Masatoshi Kitagawa

DOI: 10.2174/1568009616666151112122801

Molecular Genetics and Targeted Therapy in Hepatocellular Carcinoma

, 2016; 16(1): 53 - 70

Eric I. Marks and Nelson S. Yee

DOI: 10.2174/1568009615666150916092903

Chemotherapy Delivery Strategies to the Central Nervous System: neither Optional nor Superfluous

, 2015; 15(9): 752 - 768

Annie Drapeau and David Fortin

DOI: 10.2174/1568009615666150616123548

Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice

, 2015; 15(8): 703 - 715

Joan Maurel and Antonio Postigo

DOI: 10.2174/156800961508151001102822

Nanobiotechnological Approaches to Overcome Drug Resistance in Breast Cancer

, 2015; 15(7): 544 - 562

Peyman Ranji, Zahra Heydari and Ali Mohammad Alizadeh

DOI: 10.2174/1568009615666150706102842

Bone Metastasis: Molecular Mechanisms Implicated in Tumour Cell Dormancy in Breast and Prostate Cancer

, 2015; 15(6): 469 - 480

Lewis Quayle, Penelope D. Ottewell and Ingunn Holen

DOI: 10.2174/1568009615666150506092443

Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer

, 2015; 15(5): 394 - 405

Ryan Stuchbery, Natalie J. Kurganovs, Patrick J. McCoy, Colleen C. Nelson, Vanessa M. Hayes, Niall M. Corcoran and Christopher M. Hovens

DOI: 10.2174/1568009615666150416113453

A Pan-Cancer Review of ALK Mutations: Implications for Carcinogenesis and Therapy

, 2015; 15(4): 327 - 336

Nick Ka Ming Yau, Andrew Yuon Fong, Hiu Fung Leung, Krista Roberta Verhoeft, Qin Ying Lim, Wai Yip Lam, Ian Chi Kei Wong and Vivian Wai Yan Lui

DOI: 10.2174/1568009615666150225123712

Present, Emerging and Possible Future Biomarkers in Castration Resistant Prostate Cancer (CRPC)

, 2015; 15(3): 243 - 255

Martin Boegemann, Andres-Jan Schrader, Laura-Maria Krabbe and Edwin Herrmann

DOI: 10.2174/1568009615666150204145803

Involvement of Mesenchymal Stem Cells in Cancer Progression and Metastases

, 2015; 15(2): 88 - 98

Astra I. Chang, Aaron H. Schwertschkow, Jan A. Nolta and Jian Wu

DOI: 10.2174/1568009615666150126154151

Potential Anti-cancer Drugs Commonly Used for Other Indications

, 2015; 15(1): 35 - 52

Veronika Hanusova, Lenka Skalova, Vera Kralova and Petra Matouskova

DOI: 10.2174/1568009615666141229152812

Looking out for Cancer Stem Cells’ Properties: The Value-Driving Role of CD44 for Personalized Medicines

, 2014; 14(9): 832 - 849

Sara Horta, Ana L. Agostinho, Rita Mateus, Lucilia Pereira, Carolina Pereira, Liliana Capinha, Slavomira Doktorovova, Alexandra Brito and Mafalda Videira

DOI: 10.2174/1568009614666141111154713

Heat Shock Proteins as Prognostic Markers of Cancer

, 2014; 14(8): 713 - 726

Evgeniya V. Kaigorodova and Mariya V. Bogatyuk

DOI: 10.2174/1568009614666140926122846

Targeting Oncogenes and Tumor Suppressors genes to Mitigate Chemoresistance

, 2014; 14(7): 599 - 609

Tahereh Fatemian and Ezharul Hoque Chowdhury

DOI: 10.2174/156800961407140926104458

Overview of Proteasome Inhibitor-Based Anti-cancer Therapies: Perspective on Bortezomib and Second Generation Proteasome Inhibitors versus Future Generation Inhibitors of Ubiquitin-Proteasome System

, 2014; 14(6): 517 - 536

Q. Ping Dou and Jeffrey A. Zonder

DOI: 10.2174/1568009614666140804154511

The Activation of β1-integrin by Type I Collagen Coupling with the Hedgehog Pathway Promotes the Epithelial-Mesenchymal Transition in Pancreatic Cancer

, 2014; 14(5): 446 - 457

Wanxing Duan, Jiguang Ma, Qingyong Ma, Qinhong Xu, Jianjun Lei, Liang Han, Xuqi Li, Zheng Wang, Zheng Wu, Shifang Lv, Zhenhua Ma, Mouzhu Liu, Fengfei Wang and Erxi Wu

DOI: 10.2174/1568009614666140402105101

Metabolic Features of Melanoma: A Gold Mine of New Therapeutic Targets?

, 2014; 14(4): 357 - 370

Philippe Marchetti, Pierre Guerreschi, Jerome Kluza and Laurent Mortier

DOI: 10.2174/1568009614666140407113124

Targeting BMP9-Promoted Human Osteosarcoma Growth by Inactivation of Notch Signaling

, 2014; 14(3): 274 - 285

Ruidong Li, Wenwen Zhang, Jing Cui, Wei Shui, Liangjun Yin, Yang Wang, Hongyu Zhang, Ning Wang, Ningning Wu, Guoxin Nan, Xian Chen, Sheng Wen, Fang Deng, Hongmei Zhang, Guolin Zhou, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He and Zhong-Liang Deng

DOI: 10.2174/1568009614666140305105805

PIM1 Kinase as a Target in Prostate Cancer: Roles in Tumorigenesis, Castration Resistance, and Docetaxel Resistance

, 2014; 14(2): 105 - 114

Sheldon L. Holder and Sarki A. Abdulkadir

DOI: 10.2174/1568009613666131126113854

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