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Frontiers in Clinical Drug Research – Alzheimer Disorders



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Endorsements

"Current Alzheimer Research is a great source of the most relevant and timely research in the field of AD research."

Rudolph E. Tanzi
Massachusetts General Hospital, and Harvard Medical School, USA

Forthcoming Special Issues

Systems Genetics of Alzheimer’s disease: From GWAS to Disease Pathways


Guest Editor(s): Keshen Li
Tentative Publication Date: December, 2018
Submit Abstract via Email Download Description
Published Special Issues

Alzehmier's Disease: From Molecular Mechanisms to Psychobiological Perspective


Current Alzheimer Research, Volume 14, Number 11
Guest Editor(s): Mohammad A. Kamal, Nigel H. Greig

Authors' Comments
My experience with Bentham Science Publishers’  "Current Alzheimer Research" was positive. While the review process of the manuscript was a bit too long, on the other hand the great contribution given by the Editor in Chief to the interpretation of the data I presented was brilliant. His suggestions have greatly improved the quality of my manuscript and so at the end my experience was very positive.

Rosanna Squitt
(Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio- Fatebenefratelli, Brescia, Italy)


Current Alzheimer Research

,

Volume 16

-

Number 1



Research Article   Open Access

Asymptomatic Carriers of Presenilin-1 E318G Variant Show no Cerebrospinal Fluid Biochemical Signs Suggestive of Alzheimer’s disease in a Family with Late-onset Dementia

, 16(1): 1 - 7

Vladimiro Artuso, Luisa Benussi, Roberta Ghidoni, Soraya Moradi-Bachiller, Federica Fusco, Stefano Curtolo, Ignazio Roiter, Gianluigi Forloni and Diego Albani*


DOI: 10.2174/1567205015666181031150345


Research Article   Open Access

Intranasal Insulin Prevents Anesthesia-induced Cognitive Impairments in Aged Mice

, 16(1): 8 - 18

Xing Li, Xiaoqin Run*, Zhen Wei, Kuan Zeng, Zhihou Liang, Fang Huang, Dan Ke, Qun Wang, Jian-Zhi Wang, Rong Liu, Bin Zhang* and Xiaochuan Wang*


DOI: 10.2174/1567205015666181031145045


Research Article

Brain Network Connectivity Mediates Education-related Cognitive Performance in Healthy Elderly Adults

, 16(1): 19 - 28

Yaojing Chen, Di Qi, Ting Qin, Kewei Chen, Meishan Ai, Xin Li, He Li, Junying Zhang, Haohao Mao, Yiru Yang and Zhanjun Zhang*


DOI: 10.2174/1567205015666181022094158


Research Article   Open Access

Alterations in the Expression of Amyloid Precursor Protein Cleaving Enzymes mRNA in Alzheimer Peripheral Blood

, 16(1): 29 - 38

Prapimpun Wongchitrat*, Nattaporn Pakpian, Kuntida Kitidee, Kamonrat Phopin, Pornpatr A. Dharmasaroja and Piyarat Govitrapong


DOI: 10.2174/1567205015666181109103742


Research Article   Open Access



Research Article

[18F]-florbetaben PET/CT Imaging in the Alzheimer’s Disease Mouse Model APPswe/PS1dE9

, 16(1): 49 - 55

J. Stenzel, C. Rühlmann, T. Lindner, S. Polei, S. Teipel, J. Kurth, A. Rominger, B.J. Krause, B. Vollmar and A. Kuhla *


DOI: 10.2174/1567205015666181022095904


Review Article

Current State of Saliva Biomarkers for Aging and Alzheimer’s Disease

, 16(1): 56 - 66

Maxime François*, Caroline F. Bull, Michael F. Fenech and Wayne R. Leifert


DOI: 10.2174/1567205015666181022094924


Review Article



Articles Ahead of Print

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study


Marie Bruun*, Kristian S. Frederiksen, Hanneke F.M. Rhodius-Meester, Marta Baroni, Le Gjerum, Juha Koikkalainen, Timo Urhemaa , Antti Tolonen, Mark van Gils, Tong Tong, Ricardo Guerrero, Daniel Rueckert, Nadia Dyremose , Birgitte Bo Andersen, Anja Hviid Simonsen, Afina Lemstra, Merja Hallikainen, Sudhir Kurl, Sanna-Kaisa Herukka, Anne M. Remes, Gunhild Waldemar, Hilkka Soininen, Patrizia Mecocci, Wiesje M. van der Flier, Jyrki Lötjönen and Steen G. Hasselbalch


View Abstract View on PubMed


One-year Outcome of Shanghai Mild Cognitive Impairment Cohort Study


Bin Zhou*, Qianhua Zhao, Shinsuke Kojima, Ding Ding, Satoshi Higashide, Yoji Nagai, Qihao Guo, Tatsuo Kagimura, Masanori Fukushima and Zhen Hong*


View Abstract View on PubMed


The Temporal Relationship between Pain Intensity and Pain Interference and Incident Dementia


Ali Ezzati*, Cuiling Wang, Mindy J Katz, Carol A Derby, Andrea R. Zammit, Molly E. Zimmerman, Jelena M Pavlovic, Martin J. Sliwinski and Richard B. Lipton


View Abstract View on PubMed


Computational and In-Vitro Validation of Natural Molecules as Potential Acetylcholinesterase Inhibitors and Neuroprotective Agents


Ashwani Kumar, Vineet Mehta, Utkarsh Raj, Pritish Kumar Varadwaj, Malairaman Udayabanu, Ragothaman M. Yennamalli and Tiratha Raj Singh*


View Abstract View on PubMed


Accurate and Unbiased Quantitation of Amyloid-β Fluorescence Images Using ImageSURF


Aidan R. O’Mara, Jessica M. Collins, Anna E. King, James C. Vickers and Matthew T. K. Kirkcaldie*


View Abstract View on PubMed







Abstracts Ahead of Print


Identify compounds’s target against Alzheimer's disease based on silico approach


Yan Hu, Guangya Zhou, Chi Zhang, Mengying Zhang, Qin Chen*, Linfeng Zheng* and Bing Niu*


View Abstract


Editor's Choice

Visual Event-Related Potentials in Mild Cognitive Impairment and Alzheimer’s Disease: A Literature Review

, 2019; 16(1): 67 - 89

Cassandra Morrison*, Sheida Rabipour, Vanessa Taler, Christine Sheppard and Frank Knoefel


DOI: 10.2174/1567205015666181022101036



Intranasal Insulin Prevents Anesthesia-induced Cognitive Impairments in Aged Mice

, 2019; 16(1): 8 - 18

Xing Li, Xiaoqin Run*, Zhen Wei, Kuan Zeng, Zhihou Liang, Fang Huang, Dan Ke, Qun Wang, Jian-Zhi Wang, Rong Liu, Bin Zhang* and Xiaochuan Wang*


DOI: 10.2174/1567205015666181031145045




Stroke as a Cause of Death in Death Certificates of Patients with Dementia: A Cohort Study from the Swedish Dementia Registry

, 2018; 15(14): 1322 - 1330

Ana Subic*, Eva Zupanic, Mia von Euler, Bo Norrving, Pavla Cermakova, Dorota Religa, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek


DOI: 10.2174/1567205015666181002134155




Microdose Lithium NP03 Diminishes Pre-Plaque Oxidative Damage and Neuroinflammation in a Rat Model of Alzheimer’s-like Amyloidosis

, 2018; 15(13): 1220 - 1230

Edward N. Wilson, Sonia Do Carmo, M. Florencia Iulita, Hélène Hall, Grant L. Austin, Dan T. Jia, Janice C. Malcolm, Morgan K. Foret, Adam R. Marks, D. Allan Butterfield and A. Claudio Cuello*


DOI: 10.2174/1567205015666180904154446




Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study

, 2018; 15(12): 1106 - 1113

Friedrich Leblhuber, Kostja Steiner, Burkhard Schuetz, Dietmar Fuchs* and Johanna M. Gostner


DOI: 10.2174/1389200219666180813144834




Transcriptional Remodeling in Primary Hippocampal Astrocytes from an Alzheimer’s Disease Mouse Model

, 2018; 15(11): 986 - 1004

F. Ruffinatti, L. Tapella, I. Gregnanin, A. Stevano, G. Chiorino, P.L. Canonico, C. Distasi, A.A. Genazzani* and D. Lim*


DOI: 10.2174/1567205015666180613113924



Open Access Articles

Intranasal Insulin Prevents Anesthesia-induced Cognitive Impairments in Aged Mice

, 2019; 16(1): 8 - 18

Xing Li, Xiaoqin Run*, Zhen Wei, Kuan Zeng, Zhihou Liang, Fang Huang, Dan Ke, Qun Wang, Jian-Zhi Wang, Rong Liu, Bin Zhang* and Xiaochuan Wang*





Alterations in the Expression of Amyloid Precursor Protein Cleaving Enzymes mRNA in Alzheimer Peripheral Blood

, 2019; 16(1): 29 - 38

Prapimpun Wongchitrat*, Nattaporn Pakpian, Kuntida Kitidee, Kamonrat Phopin, Pornpatr A. Dharmasaroja and Piyarat Govitrapong




Asymptomatic Carriers of Presenilin-1 E318G Variant Show no Cerebrospinal Fluid Biochemical Signs Suggestive of Alzheimer’s disease in a Family with Late-onset Dementia

, 2019; 16(1): 1 - 7

Vladimiro Artuso, Luisa Benussi, Roberta Ghidoni, Soraya Moradi-Bachiller, Federica Fusco, Stefano Curtolo, Ignazio Roiter, Gianluigi Forloni and Diego Albani*




Stroke as a Cause of Death in Death Certificates of Patients with Dementia: A Cohort Study from the Swedish Dementia Registry

, 2018; 15(14): 1322 - 1330

Ana Subic*, Eva Zupanic, Mia von Euler, Bo Norrving, Pavla Cermakova, Dorota Religa, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek





Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study

, 2018; 15(12): 1106 - 1113

Friedrich Leblhuber, Kostja Steiner, Burkhard Schuetz, Dietmar Fuchs* and Johanna M. Gostner




Technological Solutions for Older People with Alzheimer’s Disease: Review

, 2018; 15(10): 975 - 983

Petra Maresova*, Signe Tomsone, Petre Lameski, Joana Madureira, Ana Mendes, Eftim Zdravevski, Ivan Chorbev, Vladimir Trajkovik, Moriah Ellen and Kasper Rodile





Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer’s Disease

, 2018; 15(10): 938 - 950

Martina Zverova, Eva Kitzlerova, Zdenek Fisar*, Roman Jirak, Jana Hroudova, Hana Benakova, Petra Lelkova, Pavel Martasek and Jiri Raboch





Up-regulation of DMN Connectivity in Mild Cognitive Impairment Via Network-based Cognitive Training

, 2018; 15(6): 578 - 589

Matteo De Marco, Francesca Meneghello, Cristina Pilosio, Jessica Rigon and Annalena Venneri*





Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

, 2018; 15(5): 482 - 492

Kiyomi Nishimaki, Takashi Asada*, Ikuroh Ohsawa, Etsuko Nakajima, Chiaki Ikejima, Takashi Yokota, Naomi Kamimura and Shigeo Ohta*




Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers

, 2018; 15(2): 164 - 181

Roni Manyevitch, Matthew Protas, Sean Scarpiello, Marisa Deliso, Brittany Bass, Anthony Nanajian, Matthew Chang, Stefani M. Thompson, Neil Khoury, Rachel Gonnella, Margit Trotz, D. Blaine Moore, Emily Harms, George Perry, Lucy Clunes, Angelica Ortiz, Jan O. Friedrich and Ian V.J. Murray*





Most Cited Articles


Glutamate and Mitochondria: Two Prominent Players in the Oxidative Stress-Induced Neurodegeneration

, 2016; 13(2): 185-197.

Tommaso Cassano, Lorenzo Pace, Gaurav Bedse, Angelo Michele Lavecchia, Federico De Marco, Silvana Gaetani and Gaetano Serviddio


DOI: 10.2174/1567205013666151218132725


Noradrenergic System in Down Syndrome and Alzheimer’s Disease A Target for Therapy

, 2016; 13(1): 68-83.

Cristy Phillips, Atoossa Fahimi, Devsmita Das, Fatemeh S. Mojabi, Ravikumar Ponnusamy and Ahmad Salehi


DOI: 10.2174/1567205012666150921095924


Complex and Differential Glial Responses in Alzheimer´s Disease and Ageing

, 2016; 13(4): 343-358.

José J. Rodríguez, Arthur M. Butt, Emanuela Gardenal, Vladimir Parpura and Alexei Verkhratsky


DOI: 10.2174/1567205013666160229112911


Glial Cells – The Key Elements of Alzheimer´s Disease

, 2016; 13(8): 894-911.

David Dzamba, Lenka Harantova, Olena Butenko and Miroslava Anderova


DOI: 10.2174/1567205013666160129095924





Peripheral Immune Signatures in Alzheimer Disease

, 2016; 13(7): 739-749.

David Goldeck, Jacek M. Witkowski, Tamas Fülop and Graham Pawelec


DOI: 10.2174/1567205013666160222112444




Most Accessed Articles


Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study

, 2018; 15(12): 1106-1113.

Friedrich Leblhuber, Kostja Steiner, Burkhard Schuetz, Dietmar Fuchs* and Johanna M. Gostner


DOI: 10.2174/1389200219666180813144834


Stroke as a Cause of Death in Death Certificates of Patients with Dementia: A Cohort Study from the Swedish Dementia Registry

, 2018; 15(14): 1322-1330.

Ana Subic*, Eva Zupanic, Mia von Euler, Bo Norrving, Pavla Cermakova, Dorota Religa, Bengt Winblad, Milica G. Kramberger, Maria Eriksdotter and Sara Garcia-Ptacek


DOI: 10.2174/1567205015666181002134155


The Implications of Autophagy in Alzheimer’s Disease

, 2018; 15(14): 1283-1296.

Tadanori Hamano*, Kouji Hayashi, Norimichi Shirafuji and Yasunari Nakamoto


DOI: 10.2174/1567205015666181004143432


Crosstalk between Gut Microbiota and Central Nervous System: A Focus on Alzheimer's Disease

, 2018; 15(13): 1179-1190.

Vilma M. Junges, Vera E. Closs, Guilherme M. Nogueira and Maria G.V. Gottlieb*


DOI: 10.2174/1567205015666180904155908


Interplay between the APOE Genotype and Possible Plasma Biomarkers in Alzheimer’s Disease

, 2018; 15(10): 938-950.

Martina Zverova, Eva Kitzlerova, Zdenek Fisar*, Roman Jirak, Jana Hroudova, Hana Benakova, Petra Lelkova, Pavel Martasek and Jiri Raboch


DOI: 10.2174/1567205015666180601090533


Technological Solutions for Older People with Alzheimer’s Disease: Review

, 2018; 15(10): 975-983.

Petra Maresova*, Signe Tomsone, Petre Lameski, Joana Madureira, Ana Mendes, Eftim Zdravevski, Ivan Chorbev, Vladimir Trajkovik, Moriah Ellen and Kasper Rodile


DOI: 10.2174/1567205015666180427124547



Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer's Disease

, 2015; 12(1): 32-46.

Robert J. Baranello, Krishna L. Bharani, Vasudevaraju Padmaraju, Nipun Chopra, Debomoy K. Lahiri, Nigel H. Greig, Miguel A. Pappolla and Kumar Sambamurti


DOI: 10.2174/1567205012666141218140953




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