Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 18 - Number 2


Review Article

Novel Findings of Anti-cancer Property of Propofol

, 18(2): 156 - 165

Jiaqiang Wang, Chien-shan Cheng, Yan Lu, Xiaowei Ding, Minmin Zhu, Changhong Miao* and Jiawei Chen*


DOI: 10.2174/1871520617666170912120327



Review Article

Translational Research in Cutaneous Melanoma: New Therapeutic Perspectives

, 18(2): 166 - 181

Antonio Marra, Cristina R. Ferrone, Celeste Fusciello, Giosue Scognamiglio, Soldano Ferrone, Stefano Pepe, Francesco Perri and Francesco Sabbatino*


DOI: 10.2174/1871520618666171219115335



Review Article

Spices with Breast Cancer Chemopreventive and Therapeutic Potentials: A Functional Foods Based-Review

, 18(2): 182 - 194

Aliyu Muhammad*, Mohammed Auwal Ibrahim, Ochuko Lucky Erukainure, Ibrahim Malami and Auwal Adamu


DOI: 10.2174/1871520617666170912121422



Research Article

Design and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors

, 18(2): 195 - 209

Ibrahim H. Eissa, Abeer M. El-Naggar*, Nour E.A. Abd El-Sattar and Ahmed S.A. Youssef


DOI: 10.2174/1871520617666170710182405



Research Article

Inhibition of Proliferation and Induction of Apoptosis by Thymoquinone via Modulation of TGF Family, p53, p21 and Bcl-2α in Leukemic Cells

, 18(2): 210 - 215

Mona Diab-Assaf, Josiane Semaan, Marwan El-Sabban, Soad K. Al Jaouni, Rania Azar, Mohammad Amjad Kamal and Steve Harakeh*


DOI: 10.2174/1871520617666170912133054



Research Article


Research Article

Effects of Ascorbic Acid on Tax, NF-κB and MMP-9 in Human T-cell Lymphotropic Virus Type 1 Positive Malignant T-Lymphocytes

, 18(2): 237 - 244

Steve Harakeh*, Jihane Khalife, Elias Baydoun, Rania Azar, Ahmed Al- Hejin, Elie Barbour, Esam Azhar, Aleksandra Niedzwiecki, Soad Al Jaouni, Mona Diab-Assaf, Mohammad A. Kamal and Mathias Rath


DOI: 10.2174/1871520617666170725160628



Research Article

Targeting Cell Necroptosis and Apoptosis Induced by Shikonin via Receptor Interacting Protein Kinases in Estrogen Receptor Positive Breast Cancer Cell Line, MCF-7

, 18(2): 245 - 254

Zahra Shahsavari, Fatemeh Karami-Tehrani* and Siamak Salami


DOI: 10.2174/1871520617666170919164055



Research Article

VDAC1 Mediated Anticancer Activity of Gallic Acid in Human Lung Adenocarcinoma A549 Cells

, 18(2): 255 - 262

Aikebaier Maimaiti, Amier Aili, Hureshitanmu Kuerban and Xuejun Li*


DOI: 10.2174/1871520617666170912115441



Research Article

Structure-Based Design: Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Cytotoxic Agents

, 18(2): 263 - 276

Dima A. Sabbah*, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen, Haizhen A. Zhong, Reema Abu Khalaf, Ameerah (Hasan Ibrahim), Tariq Al-Qirim, Ghassan Abu Sheikha and Mohammad S. Mubarak


DOI: 10.2174/1871520617666170911171152



Research Article

Human Fibronectin Extra-Domain B (EDB)-Specific Aptide (APTEDB) Radiolabelling with Technetium-99m as a Potent Targeted Tumour-Imaging Agent

, 18(2): 277 - 285

Mohsen Mohammadgholi, Nourollah Sadeghzadeh*, Mostafa Erfani, Saeid Abediankenari, Seyed Mohammad Abedi, Iman Emrarian, Narjes Jafari and Ramezan Behzadi


DOI: 10.2174/1871520617666170918125020



Research Article

Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein

, 18(2): 286 - 294

Zulong Liu, Hengrui Zhu, Shijin Qu, Lisha Tang, Lihuan Cao, Wenbo Yu, Xianmei Yang, Songmin Jiang, Dayuan Zhu, Changheng Tan* and Long Yu*


DOI: 10.2174/1871520617666170803155025



Research Article

New Ferrocene Compounds as Selective Cyclooxygenase (COX-2) Inhibitors: Design, Synthesis, Cytotoxicity and Enzyme-inhibitory Activity

, 18(2): 295 - 301

Shabnam Farzaneh, Elnaz Zeinalzadeh, Bahram Daraei, Soraya Shahhosseini and Afshin Zarghi*


DOI: 10.2174/1871520617666171003145533



Research Article

Stereocomplexation Assisted Assembly of Poly(γ-glutamic Acid)-graft-polylactide Nano-micelles and Their Efficacy as Anticancer Drug Carrier

, 18(2): 302 - 311

Shulin Dai, Yucheng Feng, Shuyi Li, Yuxiao Chen, Meiqing Liu, Chao Zhang*, Wei Zhang* and Yihua Yin*


DOI: 10.2174/1871520617666170911170104




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