Contents

Anti-Cancer Agents in Medicinal Chemistry, Volume 17 - Number 7


Review Article

Therapeutic Use of Brentuximab Vedotin in CD30+ Hematologic Malignancies

, 17(7): 886 - 895

Alberto Fabbri, Emanuele Cencini, Alessandro Gozzetti, Luana Schiattone and Monica Bocchia


DOI: 10.2174/1871520616666160902100506



Review Article

The Role of Tumor Suppressor DLC-1: Far From Clear

, 17(7): 896 - 901

Xu Liu, Yao-Jie Pan, Jun-Nian Zheng and Dong-Sheng Pei


DOI: 10.2174/1871520616666160907142754



Review Article

Therapeutic Challenges in Neuroendocrine Tumors

, 17(7): 902 - 919

Ioannis Legakis, Muhammad Wasif Saif and Kostantinos Syrigos


DOI: 10.2174/1871520617666170213113401



Review Article

Second Generation Proteasome Inhibitors in Multiple Myeloma

, 17(7): 920 - 926

Alessandro Gozzetti, Giulia Papini, Veronica Candi, Corrado Zuanelli Brambilla, Santina Sirianni and Monica Bocchia


DOI: 10.2174/1871520616666160902101622



Research Article

Docking and QSAR Studies of Aryl-valproic Acid Derivatives to Identify Antiproliferative Agents Targeting the HDAC8

, 17(7): 927 - 940

Heidy Martínez-Pacheco, Guillermo Ramírez-Galicia, Midalia Vergara-Arias, Jurg Gertsch, Jonathan Manuel Fragoso-Vazquez, David Mendez-Luna, A. L. Abujamra, Cabrera-Perez Laura Cristina, Rosales-Hernandez Martha Cecilia, I Mendoza-Lujambio and Jose Correa-Basurto


DOI: 10.2174/1871520616666161019143219



Research Article


Research Article

Polo-like Kinase 1-targeting Chitosan Nanoparticles Suppress the Progression of Hepatocellular Carcinoma

, 17(7): 948 - 954

Dongzhi Wang, Renan Chang, Gang Wang, Baoying Hu, Yong Qiang and Zhong Chen


DOI: 10.2174/1871520616666160926111911



Research Article

Protective Effect of Perindopril on Tumor Progression and Angiogenesis in Animal Model of Breast Cancer

, 17(7): 955 - 960

Snehal S. Patel and Surender Nakka


DOI: 10.2174/1871520616666160817143141



Research Article

Evaluation of Melatonin Effect on Human Breast Cancer Stem Cells Using a Threedimensional Growth Method of Mammospheres

, 17(7): 961 - 965

Juliana Ramos Lopes, Mayume da Silva Kavagutti, Felipe Arthur Faustino de Medeiros and Debora Aparecida Pires de Campos Zuccari


DOI: 10.2174/1871520616666160923093229



Research Article

TGF-β Signal Transduction in Pancreatic Carcinoma Cells is Sensitive to Inhibition by the Src Tyrosine Kinase Inhibitor AZM475271

, 17(7): 966 - 972

Tobias Bartscht, Benjamin Rosien, Dirk Rades, Roland Kaufmann, Harald Biersack, Hendrik Lehnert and Hendrik Ungefroren


DOI: 10.2174/1871520616666160926110513



Research Article

Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents

, 17(7): 973 - 981

Andrea Ilaria Zotti, Elena Di Gennaro, Angela Corvino, Francesco Frecentese, Elisa Magli, Elisa Perissutti, Giuseppe Cirino, Fiorentina Roviezzo, Manuela Terranova-Barberio, Federica Iannelli, Giuseppe Caliendo, Vincenzo Santagada, Ferdinando Fiorino, Alfredo Budillon and Beatrice Severino


DOI: 10.2174/1871520616666160926120904



Research Article

Mechanism and Anticancer Activity of the Metabolites of an Endophytic Fungi from Eucommia ulmoides Oliv

, 17(7): 982 - 989

Qi Li, Yan Zhang, Jun-Ling Shi, Yi-Lin Wang, Hao-Bin Zhao, Dong-yan Shao, Qing-Sheng Huang, Hui Yang and Ming-Liang Jin


DOI: 10.2174/1871520616666160923094814



Research Article

Discovery of New Aminosubstituted Pyrrolopyrimidines with Antiproliferative Activity Against Breast Cancer Cells and Investigation of their Effect Towards the PI3Kα Enzyme

, 17(7): 990 - 1002

Konstantinos Daniilides, Nikolaos Lougiakis, Thomas Evangelidis, Ioannis K. Kostakis, Nicole Pouli, Panagiotis Marakos, Emmanuel Mikros, Alexios-Leandros Skaltsounis, Stephane Bach, Blandine Baratte, Sandrine Ruchaud, Valia Karamani, Alexandra Papafotika, Savvas Christoforidis, Orestis Argyros, Eva Kouvari and Constantin Tamvakopoulos


DOI: 10.2174/1871520616666161207143450



Research Article

Design and Synthesis of 1,4-dihydropyridine Derivatives as Anti-cancer Agent

, 17(7): 1003 - 1013

Denish Viradiya, Sheefa Mirza, Faraz Shaikh, Rajesh Kakadiya, Anand Rathod, Nayan Jain, Rakesh Rawal and Anamik Shah


DOI: 10.2174/1871520616666161206143251



Research Article

Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles

, 17(7): 1014 - 1025

Samar S. Fatahala, Mosaad S. Mohamed, Mahmoud Youns and Rania H. Abd-El Hameed


DOI: 10.2174/1871520617666170102152928




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